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Akademický článek

Thyroid hormone influences conditional transcript elongation of the apolipoprotein A-I gene in rat liver

Autor: Y C Lin-Lee, S M Soyal, A Surguchov, S Sanders, W Strobl, W Patsch

Publikováno v: Journal of Lipid Research, Vol 36, Iss 7, Pp 1586-1594 (1995)

Chronic administration of thyroid hormone (T3) increases apoA-I gene expression in rat liver by enhancing mRNA maturation, but reduces apoA-I mRNA synthesis to 50% of control. To gain insight into the inverse relation of mRNA maturation and mRNA synt

Externí odkaz: https://doaj.org/article/708da99b9f2740c285202df7b8d76ff4

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In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene

Autor: J D Roberts, C D Montgomery, I Nasonkin, A Hughes, B Fang, R C Eisensmith, J Li, X H Li, Y C Lin-Lee, Martha P. Mims

Publikováno v: Journal of Clinical Investigation. 95:768-773

Elevations of plasma total or LDL cholesterol are major risk factors for cardiovascular disease. Efforts directed at preventing and treating cardiovascular disease have often focused on reducing the levels of these substances in the blood. The Watana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccec92c92e64a884fae6eeb7ccbfe615
https://doi.org/10.1172/jci117725

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Altered regulation of apolipoprotein A-IV gene expression in the liver of the genetically obese Zucker rat

Autor: Wolfgang Patsch, B Knerer, R Gratzl, K Arbeiter, W Strobl, Y C Lin-Lee

Publikováno v: Journal of Clinical Investigation. 92:1766-1773

Apolipoprotein (apo) A-IV, a structural component of chylomicrons and high-density lipoproteins, may play a role in the catabolism of triglyceride-rich lipoproteins and in reverse cholesterol transport. To study the regulation of apoA-IV gene express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bffdd0f6a0e422c81ccc7e2b1bfe36
https://doi.org/10.1172/jci116765

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Induction of MRP1 and gamma-glutamylcysteine synthetase gene expression by interleukin 1beta is mediated by nitric oxide-related signalings in human colorectal cancer cells

Autor: Y, Ikegami, S, Tatebe, Y C, Lin-Lee, Q W, Xie, T, Ishikawa, M T, Kuo

Publikováno v: Journal of cellular physiology. 185(2)

Treatment of human colorectal cancer cells HT29 with interleukin 1beta (IL-1beta) induces expression of the multidrug resistance protein (MRP1) gene encoding the ATP-dependent glutathione S-conjugate export (GS-X) pump and the gamma-glutamylcysteine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::313a5a8514021ae79286c76e693f948a
https://pubmed.ncbi.nlm.nih.gov/11025451

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Role of thyroid hormone in the expression of apolipoprotein A-IV and C-III genes in rat liver

Autor: Y C, Lin-Lee, W, Strobl, S, Soyal, M, Radosavljevic, M, Song, A M, Gotto, W, Patsch

Publikováno v: Journal of lipid research. 34(2)

The genes coding for apolipoproteins A-I, C-III, and A-IV are closely linked to one another in the rat genome. Thyroid hormone stimulates apoA-I expression in rat liver by an unusual mechanism that enhances the maturation of mRNA. This hormone also i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5527312938eed1376e4c4623fcabf5d8
https://pubmed.ncbi.nlm.nih.gov/8429259

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Regulation of Lipoprotein Gene Expression

Autor: P. Cheung, M. H. Lin-Su, T. Antalis, L. Chan, Y. C. Lin-Lee

Publikováno v: Atherosclerosis VI ISBN: 9783642818196

The application of molecular biology in the study of apolipoprotein biosynthesis has been a relatively recent event. About six years ago, our laboratory initiated a series of studies on the biosynthesis of an apolipoprotein, apoVLDL-II, in a model sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79b7ed06b4879915ae4cd36a6912e0b9
https://doi.org/10.1007/978-3-642-81817-2_109

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Effect of sucrose diet on apolipoprotein biosynthesis in rat liver. Increase in apolipoprotein E gene transcription

Autor: W, Strobl, N L, Gorder, G A, Fienup, Y C, Lin-Lee, A M, Gotto, W, Patsch

Publikováno v: The Journal of biological chemistry. 264(2)

A sucrose-rich diet stimulates the biosynthesis of very low density lipoproteins in rat liver. This diet also increases the triglyceride content of hepatic very low density lipoproteins and changes their apolipoprotein composition. To study the chang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::29bd9989ff9994339f2cf8a218046a5e
https://pubmed.ncbi.nlm.nih.gov/2463248

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Akademický článek

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Akademický článek

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