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of 5
pro vyhledávání: '"Y C L, Tung"'
More than 300 genetic variants have been robustly associated with measures of human adiposity. Highly penetrant mutations causing human obesity do so largely by disrupting satiety pathways in the brain and increasing food intake. Most of the common o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e244ac113c453f6afb6cb271f18fff2
Autor:
HG Joost, Giles S.H. Yeo, Zorica Jovanovic, Y. C. L. Tung, Hadi Al-Hasani, Reinhart Kluge, T. Dreja, Axel Rasche, Ralf Herwig
Publikováno v:
Diabetologia; Vol 53
Diabetologia
Diabetologia
Aims/hypothesis Numerous new genes have recently been identified in genome-wide association studies for type 2 diabetes. Most are highly expressed in beta cells and presumably play important roles in their function. However, these genes account for o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3633dd4e2fef6c0f86a8abc0e0698415
Autor:
Y C L Tung, Suzanne L. Dickson, Rolf Håkanson, Andreas Lindqvist, C. Dornonville de la Cour, Claes Ohlsson, Charlotte Erlanson-Albertsson, Vikas Surve, Emil Egecioglu, J-O Jansson
Publikováno v:
Gut; 54(7), pp 907-913 (2005)
Background and aims: The gastric hormone ghrelin has been reported to stimulate food intake, increase weight gain, and cause obesity but its precise physiological role remains unclear. We investigated the long term effects of gastrectomy evoked ghrel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ca317a0a3828b520b027bc687a069a
https://doi.org/10.1136/gut.2004.058578
https://doi.org/10.1136/gut.2004.058578
Publikováno v:
Journal of neuroendocrinology. 23(2)
We have addressed the question of how different rodent species cope with the life-threatening homeostatic challenge of dehydration at the level of transcriptome modulation in the supraoptic nucleus (SON), a specialised hypothalamic neurosecretory app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::224aadec32643daf76e748264e0cb523
https://pubmed.ncbi.nlm.nih.gov/21070396
https://pubmed.ncbi.nlm.nih.gov/21070396
Publikováno v:
Journal of neuroendocrinology. 17(6)
The hypothalamus appears to be more responsive to ghrelin and growth hormone secretagogues (GHS) in fasting, as reflected by a two- to three-fold increase in the number of cells detected that express Fos protein in the arcuate nucleus, in 48-h fasted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8ead5a4f356c0756d15de748a93de611
https://pubmed.ncbi.nlm.nih.gov/15929744
https://pubmed.ncbi.nlm.nih.gov/15929744