Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Y C, Awasthi"'
Autor:
Bhalchandra A. Diwan, Miriam R. Anver, Jerry M. Rice, Laura W. Fornwald, P. Chomarat, Lucy M. Anderson, Y. C. Awasthi, M A Sipowicz, Christopher P. Wild
Publikováno v:
Carcinogenesis. 18:2179-2190
Mice naturally infected by Helicobacter hepaticus develop a chronic active hepatitis leading to hepatocellular carcinoma. This mouse model of liver cancer was used to examine the impact of bacterial infection on the hepatic expression and activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9d0c4d9f7302f3b7ff9542e017bb7f
https://doi.org/10.1093/carcin/18.11.2179
https://doi.org/10.1093/carcin/18.11.2179
Publikováno v:
Toxicology and Applied Pharmacology. 119:175-180
This study investigated the catalytic activities of hepatic glutathione S-transferase (GST) isoenzymes isolated from CD-1 mice toward two activated alkenals of toxicological relevance: trans,trans-muconaldehyde (MA), a putative myelotoxic metabolite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e7f68741074e2ee59f65c3bbaefdd5
https://doi.org/10.1006/taap.1993.1058
https://doi.org/10.1006/taap.1993.1058
Publikováno v:
The Journal of biological chemistry. 276(22)
The physiological significance of the selenium-independent glutathione peroxidase (GPx) activity of glutathione S-transferases (GSTs), associated with the major Alpha class isoenzymes hGSTA1-1 and hGSTA2-2, is not known. In the present studies we dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24ea76d448f69c178903c79fb8ec0894
https://pubmed.ncbi.nlm.nih.gov/11279091
https://pubmed.ncbi.nlm.nih.gov/11279091
Autor:
S S, Singhal, B F, Godley, A, Chandra, U, Pandya, G F, Jin, M K, Saini, S, Awasthi, Y C, Awasthi
Publikováno v:
Investigative ophthalmologyvisual science. 40(11)
To delineate the role of the glutathione S-transferase (GST) isozyme hGST 5.8 in protection mechanisms against oxidative stress, the effect of low-level transient exposure of H2O2 to retinal pigmented epithelial (RPE) cells on hGST 5.8 and other enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa059a92e6306bce6eff59db514126e2
https://pubmed.ncbi.nlm.nih.gov/10509662
https://pubmed.ncbi.nlm.nih.gov/10509662
Publikováno v:
Cancer research. 58(23)
Four allelic variants of glutathione (GSH) S-transferase P1-1 (hGSTP1-1) that differ in their structures at amino acid(s) in position(s) 104 and/or 113 are known to exist in human populations. However, the physiological significance of hGSTP1-1 polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::258919d3b303c7c01856bcfa3146a01a
https://pubmed.ncbi.nlm.nih.gov/9850062
https://pubmed.ncbi.nlm.nih.gov/9850062
Autor:
X, Hu, P J, Benson, S K, Srivastava, H, Xia, R J, Bleicher, H A, Zaren, S, Awasthi, Y C, Awasthi, S V, Singh
Publikováno v:
International journal of cancer. 73(6)
There is a growing need for short-term and cost-effective bioassay to assess the efficacy of potential chemo-preventive agents. We report that the induction of glutathione (GSH) S-transferase pi (mGSTP1-1) by a chemo-preventive agent can be used as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5e2ad547c95849cffd944830c03ca23
https://pubmed.ncbi.nlm.nih.gov/9399673
https://pubmed.ncbi.nlm.nih.gov/9399673
Autor:
S, Awasthi, S S, Singhal, N, He, M, Chaubey, P, Zimniak, S K, Srivastava, S V, Singh, Y C, Awasthi
Publikováno v:
International journal of cancer. 68(3)
Energy-dependent membrane efflux pumps have been implicated in mediating resistance to doxorubicin (DOX). Membrane-transport mechanisms distinct from P-glycoprotein, capable of transporting DOX and glutathione conjugates have been reported in human c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdb97bea0b2fc2549de066e1e4ad29c6
https://pubmed.ncbi.nlm.nih.gov/8903475
https://pubmed.ncbi.nlm.nih.gov/8903475
Autor:
S, Awasthi, K K, Bajpai, J T, Piper, S S, Singhal, A, Ballatore, W E, Seifert, Y C, Awasthi, G A, Ansari
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::082e1289e7c589ce029ebbcfe92c4e4a
https://pubmed.ncbi.nlm.nih.gov/8820431
https://pubmed.ncbi.nlm.nih.gov/8820431
Autor:
S. S. Singhal, M Khan, Sanjay Awasthi, Meena Chaubey, Ghulam Ansari, D. R. Petersen, Y. C. Awasthi, S. K. Srivastava
Publikováno v:
Toxicology and applied pharmacology. 131(1)
Since previous studies from this laboratory have suggested that glutathione S-transferase (GST) 8-8 of rat belongs to a distinct subgroup of GST isozymes which may be involved in the detoxification of the products of lipid peroxidation (Zimniak et al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7dcf94dd12a4c69021b54dbfa0007d
https://pubmed.ncbi.nlm.nih.gov/7878679
https://pubmed.ncbi.nlm.nih.gov/7878679
Publikováno v:
Investigative ophthalmologyvisual science. 36(1)
To study the distribution and expression of glutathione S-transferase isozymes involved in detoxification of endogenously generated toxic products of lipid peroxidation, namely, 4-hydroxynonenal (4-HNE) in human lens, retina, cornea, iris, ciliary bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9de10af5fdcf89cb1b828bfa03204e90
https://pubmed.ncbi.nlm.nih.gov/7822141
https://pubmed.ncbi.nlm.nih.gov/7822141