Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yūji Awaga"'
Autor:
Rintaro Fujii, Yuji Awaga, Kenya Nozawa, Mayumi Matsushita, Aldric Hama, Takahiro Natsume, Hiroyuki Takamatsu
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 11, Pp 694-708 (2022)
Abstract Greater understanding of the mechanism that mediates visceral pain and hypersensitivity associated with irritable bowel syndrome (IBS) would facilitate the development of effective therapeutics to manage these symptoms. An objective marker a
Externí odkaz:
https://doaj.org/article/ff69317dcfc2428d96a6c8321d4fcc09
Autor:
Hiroki Ushirozako, Go Yoshida, Daisuke Togawa, Takao Omura, Tomohiko Hasegawa, Yu Yamato, Tomohiro Banno, Hideyuki Arima, Shin Oe, Yuki Mihara, Tomohiro Yamada, Takahiro Natsume, Shinya Ogawa, Yuji Awaga, Hiroyuki Takamatsu, Yukihiro Matsuyama
Publikováno v:
Spine Surgery and Related Research, Vol 3, Iss 4, Pp 368-376 (2019)
Introduction: There is currently a lack of translatable, preclinical models of low back pain (LBP). Chymopapain, a proteolytic enzyme used to treat lumbar intervertebral disc (IVD) herniation, could induce discogenic LBP. The current study developed
Externí odkaz:
https://doaj.org/article/598ac596ae3f484bb4d73fa7b219337a
Exploratory clinical characterization of experimentally-induced ulcerative colitis nonhuman primates
Autor:
Nobuyuki Takahashi, Chinatsu Kitazawa, Yoshitaka Itani, Yuji Awaga, Aldric Hama, Ikuo Hayashi, Hiroyuki Takamatsu
Publikováno v:
Heliyon, Vol 6, Iss 1, Pp e03178- (2020)
A limitation of currently used preclinical models of colitis is that disease and treatment assessment methods differ from clinically used methods. Thus, a modified Mayo score and an endoscopic index (EI) were developed for use in cynomolgus macaques
Externí odkaz:
https://doaj.org/article/9e0363148aa34efc8be9fa19ee668e79
Autor:
Akihisa Matsuda, Hiroyuki Takamatsu, Aldric Hama, Yoshitaka Itani, Tomomi Shirai, Takahiro Natsume, Mizuho Yano, Yūji Awaga
Publikováno v:
J Am Assoc Lab Anim Sci
Maintaining effective analgesia during invasive procedures performed under general anesthesia is important for minimizing postoperative complications and ensuring satisfactory patient wellbeing and recovery. While patients under deep sedation may dem
Autor:
Akihisa Matsuda, Takahiro Natsume, Mizuho Yano, Yūji Awaga, Ikuo Hayashi, Shinya Ogawa, Hiroyuki Takamatsu, Aldric Hama
Publikováno v:
Human Reproduction. 34:469-478
Study question Can pain be objectively assessed in macaques with naturally occurring endometriosis? Summary answer Behavioral, pharmacological and in vivo brain imaging findings indicate that pain can be quantified in macaques with endometriosis. Wha
Autor:
Ikuo Hayashi, Shinya Ogawa, Yasuhiro Magata, Hiroyuki Takamatsu, Kurumi Yamoto, Takahiro Natsume, Yuka Shidahara, Aldric Hama, Shinichi Okamoto, Yūji Awaga
Publikováno v:
Neuropharmacology. 149
The antineoplastic agent oxaliplatin is a first-line treatment for colorectal cancer. However, neuropathic pain, characterized by hypersensitivity to cold, emerges soon after treatment. In severe instances, dose reduction or curtailing treatment may
Autor:
Kanae Murata, Kenya Nozawa, Mayumi Matsushita, Aozora Yamashita, Rintaro Fujii, Yuji Awaga, Aldric Hama, Takahiro Natsume, Go Yoshida, Yukihiro Matsuyama, Hiroyuki Takamatsu
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 11, Pp 2466-2473 (2023)
The lack of truly robust analgesics for chronic pain is owed, in part, to the lack of an animal model that reflects the clinical pain state and of a mechanism-based, objective neurological indicator of pain. The present study examined stimulus-evoked
Externí odkaz:
https://doaj.org/article/d5149586a4f340faa82428461d99c768