Zobrazeno 1 - 10 of 27 pro vyhledávání: '"YūF. Sasaki"'
1
Development of genotoxicity assay systems that use aquatic organisms
Autor: YūF. Sasaki, T. Ueda, Norio Tanaka, Toshio Sofuni, Naohide Kinae, Y. Ojima, K. Wada, K. Saotome, Makoto Hayashi, K. Uyeno, Norihide Asano, Akinori Takai
Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 399:125-133
Our aim is to develop and evaluate monitoring systems that use aquatic organisms to assess the genotoxicity of water in the field and in the laboratory. In a field study, we have shown that the micronucleus assay is applicable to freshwater and marin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caa842adf8ddf88f1725134201fdb05
https://doi.org/10.1016/s0027-5107(97)00251-0
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2
Detection of genotoxicity of polluted sea water using shellfish and the alkaline single-cell gel electrophoresis (SCE) assay: a preliminary study
Autor: Emi Nishidate, Naonori Matsusaka, Shuji Tsuda, YūF. Sasaki, Norihide Asano, Kyoko Saotome, Satoko Ishibashi, Toshio Sofuni, Makoto Hayashi, Fusako Izumiyama
Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 393:133-139
We exposed two species of shellfish, Patunopecten yessoensis and Tapes japonica , for 4 h to artificial sea water in which N -methyl- N ′-nitro- N -nitrosoguanidine (MNNG), ethyl nitrosourea (EMS), 3-chloro-4-dichloromethyl-5-hydroxy-2( H )-furanon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909212427a89c7a9a42198acf40b59a0
https://doi.org/10.1016/s1383-5718(97)00098-3
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3
Detection of in vivo genotoxicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) by the alkaline single cell gel electrophoresis (Comet) assay in multiple mouse organs
Autor: Naohide Kinae, Naonori Matsusaka, Fusako Izumiyama, Mie Watanabe-Akanuma, Shuji Tsuda, Emi Nishidate, YūF. Sasaki
Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 393:47-53
We tested the genotoxicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5 H ]-furanone (MX) in the mouse in 6 organs (liver, lung, kidney, brain, spleen, and bone marrow) and in the mucosa of stomach, jejunum, ileum, colon, and bladder using the alkali
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5f0c15f31e053d8778f68cde3507f4
https://doi.org/10.1016/s1383-5718(97)00085-5
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4
Simple detection of in vivo genotoxicity of pyrimethamine in rodents by the modified alkaline single-cell gel electrophoresis assay
Autor: Emi Nishidate, Shuji Tsuda, YūF. Sasaki, Naonori Matsusaka, Tomoko Ono, Fusako Izumiyama, Toshihiro Ohta
Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 392:251-259
We tested the genotoxicity of pyrimethamine in 5 mouse and rat organs (liver, lung, kidney, spleen, and bone marrow) using a modified alkaline single-cell gel electrophoresis (SCG) (Comet) assay. Mice and rats were sacrificed 1, 3, 6, and 24 h after
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587e9f30627ee26dac2cc6368e0f6836
https://doi.org/10.1016/s1383-5718(97)00079-x
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5
Antimutagenicity of Tochu tea (an aqueous extract of Eucommia ulmoides leaves): 2. Suppressing effect of Tochu tea on the urine mutagenicity after ingestion of raw fish and cooked beef
Autor: Aki Chiba, Makiko Tanaka, Sayuri Moribayashi, Yasuko Hara, Kaoru Sekihashi, Chihiro Kudou, Takanori Nakamura, YūF. Sasaki, Mikako Takahoko, Michiko Murakami, Yoshihisa Nakazawa, Shigenori Onizuka
Publikováno v: Mutation Research/Genetic Toxicology. 371:203-214
The effect of Tochu tea, which is an aqueous extract of Eucommia ulmoides leaves and a popular beverage in Japan, on the urine mutagenicity before and after ingestion of raw fish and cooked beef was studied using Salmonella typhimurium YG1024. Urines
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a86317f6fdfc5036eb55ea901cbcdd
https://doi.org/10.1016/s0165-1218(96)90108-1
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6
Bio-anticlastogenic effects of unsaturated fatty acids included in fish oil — docosahexaenoic acid, docosapentaenoic acid, and eicosapentaenoic acid — in cultured Chinese hamster cells
Autor: Hiroshi Yamada, Tatsunori Yamagishi, Yasuhiko Shirasu, YūF. Sasaki, Masayuki Sakaguchi
Publikováno v: Mutation Research/Genetic Toxicology. 320:9-22
Bio-anticlastogenic effects of unsaturated fatty acids--cis-4,7,10,13,16,19-docosahexaenoic acid (DHA), cis-7,10,13,16,19-docosapentaenoic acid (DPA), and cis-5,8,11,14,17-eicosapentaenoic acid (EPA)--on chemically induced chromosome aberrations were
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4f595a1a97cc672912c4e36f452ed6
https://doi.org/10.1016/0165-1218(94)90055-8
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7
Suppressing effects of S phase post-treatment with carbolines on sister-chromatid exchanges induced by mitomycin C in Chinese hamster cells
Autor: YūF. Sasaki, Yasuhiko Shirasu
Publikováno v: Mutation Research Letters. 302:165-171
The effects of post-treatment with four types of carbolines-alpha-, beta-, gamma-, and delta-carbolines-and aminoimidazoazaarenes during S phase on the frequency of SCEs induced by MMC were studied in synchronized Chinese hamster CHO cells. Post-trea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516b318fda73c91e6a827771d9334ece
https://doi.org/10.1016/0165-7992(93)90044-v
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8
The clastogen-suppressing effects of green tea, Po-lei tea and Rooibos tea in CHO cells and mice
Autor: YūF. Sasaki, Hiroshi Yamada, Naohide Kinae, Kunihiko Kator, Kayoko Shimoi
Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 286:221-232
The suppressing effects of crude extracts of three kinds of tea-green tea (GT) from Japan, Po-lei tea (PT) from China, and Rooibos tea (RT) from South Africa-on the induction of chromosome aberrations in cultured CHO cells and mice were studied. When
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bef0eabfacfbf69d147443361486bdf
https://doi.org/10.1016/0027-5107(93)90187-k
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9
Tea tannin components modify the induction of sister-chromatid exchanges and chromosome aberrations in mutagen-treated cultured mammalian cells and mice
Autor: Yasuhiko Shirasu, YūF. Sasaki, Toshihiro Ohta, Mie Watanabe, Hisako Imanishi, Tomoko Kato
Publikováno v: Mutation Research/Genetic Toxicology. 259:79-87
The modifying effects of tannin components extracted from green tea and black tea on mutagen-induced SCEs and chromosome aberrations were studied. These tannin components did not affect spontaneous SCEs and chromosome aberrations in cultured Chinese
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10e3b5c5930b9d4c0f9ab84f3b45f9c
https://doi.org/10.1016/0165-1218(91)90111-x
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10
Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow)
Autor: YūF. Sasaki, Emi Nishidate, Shuji Tsuda, Naonori Matsusaka, Fusako Izumiyama
Publikováno v: Mutation research. 391(3)
We have recently designed a simple method for applying the alkaline single-cell gel electrophoresis (SCG) assay to mouse organs. With this method, each organ is minced, suspended in chilled homogenizing buffer containing NaCl and Na2EDTA, gently homo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e81991928e138436b9d8b79a6181f4
https://pubmed.ncbi.nlm.nih.gov/9268046
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