Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Y, Somers"'
Publikováno v:
British Journal of Pharmacology. 161:1444-1454
BACKGROUND AND PURPOSE In cardiovascular pharmacology, electrical and mechanical events can be distinguished, and the phrase ‘electro-mechanical window’ (EMw) describes the temporal difference between these events. We studied whether changes in E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2da7d411e9354382ebbc02441c6f89f
https://doi.org/10.1111/j.1476-5381.2010.00934.x
https://doi.org/10.1111/j.1476-5381.2010.00934.x
Publikováno v:
Minerva anestesiologica. 79(12)
Neurally Adjusted Ventilatory Assist (NAVA) offers synchronized proportional pressure in accordance with the electrical activity of the diaphragm (EAdi). NAVA relies on the EAdi to trigger the respiratory cycle and then adjusts the ventilatory assist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a48b44caef1347b649b48c31bb682db
https://pubmed.ncbi.nlm.nih.gov/23811628
https://pubmed.ncbi.nlm.nih.gov/23811628
Publikováno v:
British journal of pharmacology. 161(7)
In cardiovascular pharmacology, electrical and mechanical events can be distinguished, and the phrase 'electro-mechanical window' (EMw) describes the temporal difference between these events. We studied whether changes in EMw have potential predictiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0cefb04133f784c2ce33845565c3323
https://pubmed.ncbi.nlm.nih.gov/20698854
https://pubmed.ncbi.nlm.nih.gov/20698854
Autor:
Y. Somers, Bruno Van Deuren, Roel Straetemans, Frank Cools, Henk van der Linde, Karel Van Ammel, David J. Gallacher
Publikováno v:
Journal of pharmacological and toxicological methods. 60(1)
The purpose of conducting cardiovascular safety pharmacology studies is to investigate the pharmacological profiles of new molecular entities (NMEs) and provide data that can be used for optimization of a possible new drug, and help make a selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e34df28712cf2c73ab0836c6e5ce89
https://pubmed.ncbi.nlm.nih.gov/19422925
https://pubmed.ncbi.nlm.nih.gov/19422925
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 2(5)
Ridogrel, a potent thromboxane A2 (TXA2) synthase inhibitor, also has thromboxane A2 prostaglandin endoperoxide (TXA2/PG-END) receptor antagonistic properties as documented in functional studies of human platelets. In the present study, the binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2ef38648113396802a5a469c93be3b
https://pubmed.ncbi.nlm.nih.gov/1838285
https://pubmed.ncbi.nlm.nih.gov/1838285
Publikováno v:
Biochemical Pharmacology. 35:883-891
Ketoconazole inhibits in vitro (IC50:2.6 X 10(-5) M) the formation of 5-HETE and LTB4 by isolated, carrageenin-elicited rat peritoneal PMN leukocytes, challenged with the Ca2+-ionophore A23187 in the presence of [14C]-arachidonic acid ([14C]-AA). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff91640179984e89041496380d6999a
https://doi.org/10.1016/0006-2952(86)90072-9
https://doi.org/10.1016/0006-2952(86)90072-9
Publikováno v:
Initial Reports of the Deep Sea Drilling Project, 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ed6d132bcd9412f2fb594eba745aeec
https://doi.org/10.2973/dsdp.proc.50.119.1980
https://doi.org/10.2973/dsdp.proc.50.119.1980
Publikováno v:
The Journal of biological chemistry. 264(6)
The putative roles for the second messenger, diacylglycerol, were investigated in intact platelets using a novel diacylglycerol kinase inhibitor, R 59 949, or (3-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-2,3- dihydro-2-thioxo-4(1H)-qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccf451514dafa28e27d84158c395e46a
https://pubmed.ncbi.nlm.nih.gov/2536741
https://pubmed.ncbi.nlm.nih.gov/2536741
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