Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Y, Ohkawara"'
Autor:
K, Kumagai, I, Ohno, S, Okada, Y, Ohkawara, K, Suzuki, T, Shinya, H, Nagase, K, Iwata, K, Shirato
Publikováno v:
The Journal of Immunology. 162:4212-4219
Although matrix metalloproteinases (MMPs) have been reported to play crucial roles in the migration of inflammatory cells through basement membrane components in vitro, the role of MMPs in the in vivo accumulation of the cells to the site of inflamma
Autor:
Manel Jordana, J Gauldie, Y Ohkawara, Martin R. Stämpfli, Zhou Xing, X.-F. Lei, Kenneth Croitoru
Publikováno v:
Clinical and Experimental Immunology. 113:157-165
SUMMARYTo investigate the role of GM-CSF in asthmatic airways inflammation, we have targeted GM-CSF transgene to the airway cells in a mouse model of ovalbumin (OVA)-induced allergic airways inflammation, a model in which there is marked induction of
Autor:
C. Mastruzzo, Robert A. Marr, Y Ohkawara, Zhou Xing, Manel Jordana, X.-F. Lei, Denis P. Snider, Martin R. Stämpfli
Publikováno v:
Journal of Clinical Investigation. 101:1342-1353
The objective of this study was to investigate the contribution of the interaction between CD40 and its ligand (CD40L) to antigen-induced airways inflammatory responses. To this end, we used a model involving ovalbumin (OVA) sensitization followed by
Publikováno v:
Journal of Clinical Investigation. 97:1102-1110
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pleiotropic cytokine whose expression is increased in numerous respiratory diseases, particularly in asthma. However, the role of GM-CSF in the pathogenesis of these conditions in vivo re
Publikováno v:
The European respiratory journal. 17(4)
The objectives of this study were to test the hypothesis that x-irradiation inhibits the late asthmatic response (LAR) without influencing the early asthmatic response (EAR) and to examine the mechanism of the inhibitory effect.Twenty sensitized guin
Publikováno v:
Arerugi = [Allergy]. 48(6)
Although glucocorticoid is the most effective agent for bronchial asthma, its systemic administration leads to suppression of adrenocortical function. Rapid ACTH test has been performed for assessing the function of the hypothalamic-pituitary-adrenoc
Autor:
N, Nakazawa, T, Okamoto, M, Kobayashi, T, Iwai, Y, Sasai, A, Tamura, S, Horiike, S, Yokota, M, Taniwaki, K, Kashima, S, Misawa, S, Tuda, Y, Ohkawara
Publikováno v:
The Japanese journal of antibiotics. 51(8)
Thirty three patients with severe infections associated with hematological disorders were treated with panipenem/betamipron as a second line chemotherapy. Of these, 30 patients were evaluated for effectiveness. An excellent response was obtained in 1
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 39(9)
Using an Isolex 300 immunomagnetic cell separator, we carried out CD34+ cell selection in samples from 4 patients with solid tumors: 2 patients with relapsed breast cancer, 1 post-operative patient with advanced breast cancer, and 1 post-operative pa
Publikováno v:
Gene therapy. 4(2)
Interleukin-10 (IL-10) is a potent anti-inflammatory/immune cytokine and has received growing attention for its therapeutic potential. To aid therapeutic studies of IL-10 in vivo, a replication-deficient adenoviral vector expressing mouse IL-10 was c
Autor:
Jerry Dolovich, M Glibetic, Manel Jordana, Y Ohkawara, K Nakano, Kenneth Croitoru, Zhou Xing, Peter F. Weller, Kaiser G. Lim
In this study, we have investigated CD40 expression in human peripheral blood eosinophils and in human chronically inflamed nasal tissues, i.e., nasal polyps. We show by both reverse transcriptase-PCR and Northern blot analysis that eosinophils from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5006fa1f3abc5d2064b06a52d918a4
https://europepmc.org/articles/PMC507241/
https://europepmc.org/articles/PMC507241/