Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins

Autor: Sergey A. Dyshlovoy, Wael Y. Mansour, Natalia A. Ramm, Jessica Hauschild, Maxim E. Zhidkov, Malte Kriegs, Alexandra Zielinski, Konstantin Hoffer, Tobias Busenbender, Ksenia A. Glumakova, Pavel V. Spirin, Vladimir S. Prassolov, Derya Tilki, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Abstract Fascaplysin is a red cytotoxic pigment with anticancer properties isolated from the marine sponge Fascaplysinopsis sp. Recently, structure–activity relationship analysis reported by our group suggested that selective cytotoxicity of fascap

Externí odkaz: https://doaj.org/article/df82a4dc141245f18a09fe909aa98ef5

2022 Brief Practice Update on Intravenous Thrombolysis Before Thrombectomy in Patients With Large Vessel Occlusion Acute Ischemic Stroke: A Statement from Society of Vascular and Interventional Neurology Guidelines and Practice Standards (GAPS) Committee

Autor: Hesham E. Masoud, Adam de Havenon, Alicia C. Castonguay, Kaiz S. Asif, Thanh N. Nguyen, Brijesh Mehta, Mohamad Abdalkader, Santiago Ortega Gutierrez, Thabele M. Leslie‐Mazwi, Ossama Y. Mansour, Alice Ma, Alexandra L. Czap, Cynthia L. Kenmuir, Sunil A. Sheth, Roberta Novakovic‐White, May Nour, Ashutosh P. Jadhav, Vallabh Janardhan, Ameer E. Hassan, David S. Liebeskind, Amer M. Malik, Osama O. Zaidat

Publikováno v: Stroke: Vascular and Interventional Neurology, Vol 2, Iss 4 (2022)

Background The Society of Vascular & Interventional Neurology Guidelines and Practice Standards committee established the “Brief Practice Update” format to provide up‐to‐date recommendations on focused clinical topics with emerging clinical t

Externí odkaz: https://doaj.org/article/8343d671a41a4e09956a9df5107498d2

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Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers

Autor: Rania Y. Mansour, Radwa ElBorolossy, Sara M. Shaheen, Nagwa A. Sabri

Publikováno v: European Journal of Clinical Pharmacology. 78:1935-1944

Purpose The purpose of this study is to investigate the effect of sildenafil a CYP3A4 substrate and inhibitor on the pharmacokinetics and safety of saxagliptin. Methods Eighteen healthy volunteers were recruited in sequential; single-center study to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff9e115970082d82b87c696a6bb0f145
https://doi.org/10.1007/s00228-022-03397-w

International controlled study of revascularization and outcomes following COVID‐positive mechanical thrombectomy

Autor: Adam A, Dmytriw, Sherief, Ghozy, Ahmad, Sweid, Michel, Piotin, Kimon, Bekelis, Nader, Sourour, Eytan, Raz, Daniel, Vela-Duarte, Italo, Linfante, Guilherme, Dabus, Max, Kole, Mario, Martínez-Galdámez, Shahid M, Nimjee, Demetrius K, Lopes, Ameer E, Hassan, Peter, Kan, Mohammad, Ghorbani, Michael R, Levitt, Simon, Escalard, Symeon, Missios, Maksim, Shapiro, Fréderic, Clarençon, Mahmoud, Elhorany, Rizwan A, Tahir, Patrick P, Youssef, Aditya S, Pandey, Robert M, Starke, Kareem, El Naamani, Rawad, Abbas, Ossama Y, Mansour, Jorge, Galvan, Joshua T, Billingsley, Abolghasem, Mortazavi, Melanie, Walker, Mahmoud, Dibas, Fabio, Settecase, Manraj K S, Heran, Anna L, Kuhn, Ajit S, Puri, Bijoy K, Menon, Sanjeev, Sivakumar, Ashkan, Mowla, Salvatore, D'Amato, Alicia M, Zha, Daniel, Cooke, Justin E, Vranic, Robert W, Regenhardt, James D, Rabinov, Christopher J, Stapleton, Mayank, Goyal, Hannah, Wu, Jake, Cohen, David, Turkel-Parella, Andrew, Xavier, Muhammad, Waqas, Vincent, Tutino, Adnan, Siddiqui, Gaurav, Gupta, Anil, Nanda, Priyank, Khandelwal, Cristina, Tiu, Pere C, Portela, Natalia, Perez de la Ossa, Xabier, Urra, Mercedes, de Lera, Juan F, Arenillas, Marc, Ribo, Manuel, Requena, Mariangela, Piano, Guglielmo, Pero, Keith, De Sousa, Fawaz, Al-Mufti, Zafar, Hashim, Sanjeev, Nayak, Leonardo, Renieri, Rose, Du, Mohamed A, Aziz-Sultan, David, Liebeskind, Raul G, Nogueira, Mohamad, Abdalkader, Thanh N, Nguyen, Nicholas, Vigilante, James E, Siegler, Jonathan A, Grossberg, Hassan, Saad, Michael R, Gooch, Nabeel A, Herial, Robert H, Rosenwasser, Stavropoula, Tjoumakaris, Aman B, Patel, Ambooj, Tiwari, Pascal, Jabbour

Publikováno v: European Journal of Neurology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Background and purpose Previous studies suggest that mechanisms and outcomes in patients with COVID-19-associated stroke differ from those in patients with non-COVID-19-associated strokes, but there is limited comparative evidence focusing on these p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f7171db78585427457cd3c8ce6a233
https://doi.org/10.1111/ene.15493