Zobrazeno 1 - 10
of 10 216
pro vyhledávání: '"Y, Lim"'
Autor:
Xin Huang, Chris Fowler, Yihan Li, Qiao-Xin Li, Jiaqi Sun, Yijun Pan, Liang Jin, Keyla A. Perez, Céline Dubois, Yen Y. Lim, Candace Drysdale, Rebecca L. Rumble, Holly R. Chinnery, Christopher C. Rowe, Ralph N. Martins, Paul Maruff, James D. Doecke, Yong Lin, Abdel A. Belaidi, Kevin J. Barnham, Colin L. Masters, Ben J. Gu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Impaired clearance of amyloid β (Aβ) in late-onset Alzheimer’s disease (AD) affects disease progression. The role of peripheral monocytes in Aβ clearance from the central nervous system (CNS) is unclear. We use a flow cytometry assay to
Externí odkaz:
https://doaj.org/article/3d0335505eb94001ae1c6a1edbac7289
NOS3 regulates angiogenic potential of human induced pluripotent stem cell-derived endothelial cells
Autor:
Anne M. Kong, Zulhusni A. Idris, Daniel Urrutia-Cabrera, Jarmon G. Lees, Ren Jie Phang, Geraldine M. Mitchell, Raymond C.B. Wong, Shiang Y. Lim
Publikováno v:
Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101876- (2024)
Incorporation of blood capillaries in engineered tissues and their functional connection to host blood vessels is essential for success in engineering vascularized tissues, a process which involves spatial patterning of endothelial cells (ECs) to for
Externí odkaz:
https://doaj.org/article/3bda5a01d9c2428a96a8000999628684
Autor:
Cameron Chalker, Burçak Yilmaz, Kristin Trone, Genevieve Parecki, Athena Chen, James Y. Lim, Nadine Mallak, Alexandra O. Sokolova
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)
Abstract Prostate cancer (PCa) seldom metastasizes to the thyroid gland, and only a limited number of cases are documented in the literature. The application of a relatively recent and highly sensitive imaging technique, prostate-specific membrane an
Externí odkaz:
https://doaj.org/article/49996ad4cfdc479dada9f68cd6ed13ed
Autor:
Fangyi Tan, Benjamin P. Horton, Lin Ke, Tanghua Li, Jennifer Quye-Sawyer, Joanne T. Y. Lim, Dongju Peng, Zihan Aw, Shi Jun Wee, Jing Ying Yeo, Ivan Haigh, Xianfeng Wang, Lin Thu Aung, Andrew Mitchell, Gina Sarkawi, Xinnan Li, Nurul Syafiqah Tan, Aron J. Meltzner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Late Holocene relative sea-level (RSL) data are important to understand the drivers of RSL change, but there is a lack of precise RSL records from the Sunda Shelf. Here, we produced a Late Holocene RSL reconstruction from coral microatolls i
Externí odkaz:
https://doaj.org/article/8d6b88fb3c4643f98a9ca2c7a94163a6
Autor:
S. H. Ooi, K. P. Ng, Pavai Sthaneshwar, S. K. Lim, P. Y. Khor, J. Y. Lim, W. S. Siow, K. W. Lim, Muhummad Azlan
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background The commonest indication for hospitalization in COVID-19 patients is hypoxemia or severe respiratory symptoms. However, COVID-19 disease may result in extrapulmonary complications including kidney-related pathology. The reported i
Externí odkaz:
https://doaj.org/article/528f9a6edbf4412bad5e3db295d4a893
Autor:
Jarmon G. Lees, David W. Greening, David A. Rudd, Jonathon Cross, Ayeshah A. Rosdah, Xiangfeng Lai, Tsung Wu Lin, Ren Jie Phang, Anne M. Kong, Yali Deng, Simon Crawford, Jessica K. Holien, Derek J. Hausenloy, Hsin-Hui Shen, Shiang Y. Lim
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 9, Iss , Pp 100085- (2024)
Dynamin-related protein 1 (Drp1) is a mitochondrial fission protein and a viable target for cardioprotection against myocardial ischaemia-reperfusion injury. Here, we reported a novel Drp1 inhibitor (DRP1i1), delivered using a cardiac-targeted nanopa
Externí odkaz:
https://doaj.org/article/c5ae7e34af804835a24c75f371f23c34
Autor:
Manisha Saigal, Hannah Ng Shueh Yi, Nageen Ayesha Rameez, Siebe van Manen, Bui Tr Van Anh, Vidhi P. Arora, Kai Ding Max Han, Jenelle Qian Tong Lee, Adlan Syaddad, Claudia Kexin Tan, Elisa X. Y. Lim, Benjamin J. Wainwright
Publikováno v:
Royal Society Open Science, Vol 11, Iss 9 (2024)
The global decline of shark populations, largely driven by overfishing to supply the shark fin trade, poses a significant threat to marine ecosystems. Southeast Asia, and particularly Singapore, is a key hub for the transit and trade of shark fins th
Externí odkaz:
https://doaj.org/article/06bc62b221c0424faec52e57ab51a7cc
Autor:
Joe K.C. Lee, Terence Y.X. Law, Liang Shen, Gregory X.W. Pek, Qi Y. Lim, Yi Q. Tan, Jun Y. Chia, Man K. Li
Publikováno v:
Prostate International, Vol 12, Iss 1, Pp 27-34 (2024)
Background: Chronic pelvic pain syndrome (CPPS) is a complex condition that is often difficult to treat and may sometimes require a multidisciplinary team. Among the wide array of treatment options is extracorporeal shockwave therapy (ESWT). However,
Externí odkaz:
https://doaj.org/article/5ca6b13dfd094a2799481b108292eb0d
Autor:
Yask Gupta, David J. Friedman, Michelle T. McNulty, Atlas Khan, Brandon Lane, Chen Wang, Juntao Ke, Gina Jin, Benjamin Wooden, Andrea L. Knob, Tze Y. Lim, Gerald B. Appel, Kinsie Huggins, Lili Liu, Adele Mitrotti, Megan C. Stangl, Andrew Bomback, Rik Westland, Monica Bodria, Maddalena Marasa, Ning Shang, David J. Cohen, Russell J. Crew, William Morello, Pietro Canetta, Jai Radhakrishnan, Jeremiah Martino, Qingxue Liu, Wendy K. Chung, Angelica Espinoza, Yuan Luo, Wei-Qi Wei, Qiping Feng, Chunhua Weng, Yilu Fang, Iftikhar J. Kullo, Mohammadreza Naderian, Nita Limdi, Marguerite R. Irvin, Hemant Tiwari, Sumit Mohan, Maya Rao, Geoffrey K. Dube, Ninad S. Chaudhary, Orlando M. Gutiérrez, Suzanne E. Judd, Mary Cushman, Leslie A. Lange, Ethan M. Lange, Daniel L. Bivona, Miguel Verbitsky, Cheryl A. Winkler, Jeffrey B. Kopp, Dominick Santoriello, Ibrahim Batal, Sérgio Veloso Brant Pinheiro, Eduardo Araújo Oliveira, Ana Cristina Simoes e Silva, Isabella Pisani, Enrico Fiaccadori, Fangming Lin, Loreto Gesualdo, Antonio Amoroso, Gian Marco Ghiggeri, Vivette D. D’Agati, Riccardo Magistroni, Eimear E. Kenny, Ruth J. F. Loos, Giovanni Montini, Friedhelm Hildebrandt, Dirk S. Paul, Slavé Petrovski, David B. Goldstein, Matthias Kretzler, Rasheed Gbadegesin, Ali G. Gharavi, Krzysztof Kiryluk, Matthew G. Sampson, Martin R. Pollak, Simone Sanna-Cherchi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract African Americans have a significantly higher risk of developing chronic kidney disease, especially focal segmental glomerulosclerosis -, than European Americans. Two coding variants (G1 and G2) in the APOL1 gene play a major role in this di
Externí odkaz:
https://doaj.org/article/9f6233ad88a44f828fd1c0264b712139
Publikováno v:
Cells, Vol 13, Iss 16, p 1364 (2024)
Macroautophagy (hereafter autophagy) is a cellular recycling process that degrades cytoplasmic components, such as protein aggregates and mitochondria, and is associated with longevity and health in multiple organisms. While mounting evidence support
Externí odkaz:
https://doaj.org/article/23b6178a2243444c8caadc23acb790cd