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Estrogen controls expression and bioresponse of 1,25-dihydroxyvitamin D receptors in the rat colon

Autor: B, Schwartz, P, Smirnoff, S, Shany, Y, Liel

Publikováno v: Molecular and cellular biochemistry. 203(1-2)

Estrogen receptors are extensively expressed in the gastrointestinal tract, however their physiological role is not clear yet. Estrogen and 1,25-dihydroxyvitamin D [1,25(OH)2D3] apparently share common activities in the intestine such as growth-suppr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ee8c0729a3850d3c094c26f9b9e6b2e5
https://pubmed.ncbi.nlm.nih.gov/10724336

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The protective effect of estrogen against chemically induced murine colon carcinogenesis is associated with decreased CpG island methylation and increased mRNA and protein expression of the colonic vitamin D receptor

Autor: P, Smirnoff, Y, Liel, J, Gnainsky, S, Shany, B, Schwartz

Publikováno v: Oncology research. 11(6)

Epidemiological studies suggest that estrogen prevents neoplastic transformation in the intestinal mucosa. Estrogen was shown to increase the expression of vitamin D receptors (VDR) in a variety of tissues. 1,25-Dihydroxyvitamin D [1,25-(OH)2D] and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05b0f32b55007bb954fad9e2d1861775
https://pubmed.ncbi.nlm.nih.gov/10691027

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Differential effect of TPA on PGE2 and cicaprost-induced cAMP synthesis in UMR-106 cells

Autor: M, Khanin, Y, Liel, G, Rimon

Publikováno v: Cellular signalling. 11(3)

PGE2 and prostacyclin each enhance cAMP synthesis in the osteoblast-like cell line UMR-106. The amount of cAMP induced by PGE2 was 5-7-fold greater than the amount induced by cicaprost or iloprost, stable prostacyclin analogues. Both PGE2 and the two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5581000989330e1d3e3538966db1cb0
https://pubmed.ncbi.nlm.nih.gov/10353690

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Estrogen increases 1,25-dihydroxyvitamin D receptors expression and bioresponse in the rat duodenal mucosa

Autor: Y, Liel, S, Shany, P, Smirnoff, B, Schwartz

Publikováno v: Endocrinology. 140(1)

Menopause and estrogen deficiency are associated with apparent intestinal resistance to vitamin D, which can be reversed by estrogen replacement. The in vivo influence of estrogens on duodenal vitamin D receptor (VDR) was studied in three groups of r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dfb0455b3eace2c4d363823afce244a
https://pubmed.ncbi.nlm.nih.gov/9886836

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