Výsledky vyhledávání

Multiparametric human hepatocellular carcinoma characterization and therapy response evaluation by hyperpolarized13C MRSI

Autor: Markus Schwaiger, Steffen J. Glaser, Rolf F. Schulte, Y Kosanke, Markus Durst, Marion I. Menzel, Claudia Gross, Concetta V. Gringeri, Stephan Düwel, Axel Haase, Martin A. Janich, Rickmer Braren

Publikováno v: NMR in Biomedicine. 29:952-960

Individual tumor characterization and treatment response monitoring based on current medical imaging methods remain challenging. This work investigates hyperpolarized (13) C compounds in an orthotopic rat hepatocellular carcinoma (HCC) model system b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fd76269c1ab4fe43da55466dd4aceb0
https://doi.org/10.1002/nbm.3561

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Optoacoustic Imaging and Staging of Inflammation in a Murine Model of Arthritis

Autor: Kai Licha, Y Kosanke, C.E. von Schacky, Vasilis Ntziachristos, Axel Walch, Melanie A. Kimm, Reinhard Meier, Antonio Nunes, Michaela Aichler, Ernst J. Rummeny, Nicolas Beziere

Publikováno v: Arthritis & Rheumatology. 66:2071-2078

Objective Rheumatoid arthritis (RA) is one of the most frequent inflammatory diseases, causing pain and disability in the affected joints. Early diagnosis is essential for the efficiency of symptom-targeting treatments, but its diagnosis requires car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e91178fb03577ea388fd313c149ad4c
https://doi.org/10.1002/art.38642

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Reference region-based pharmacokinetic modeling in quantitative dynamic contract-enhanced MRI allows robust treatment monitoring in a rat liver tumor model despite cardiovascular changes

Autor: Markus Schwaiger, Y Kosanke, Andreas Steingoetter, Rickmer Braren, René M. Botnar, Ernst J. Rummeny, Jonas Svensson

Publikováno v: Magnetic Resonance in Medicine. 65:229-238

In this work, two pharmacokinetic modeling techniques, population arterial input function model, and reference region model, were applied to dynamic contract-enhanced MRI data, to test the influence of a change in heart rate on modeling parameters. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e91070cdc3231fd6a693d106359e87f2
https://doi.org/10.1002/mrm.22589

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Polyglycerolsulfate functionalized gold nanorods as optoacoustic signal nanoamplifiers for in vivo bioimaging of rheumatoid arthritis

Autor: Claudio E. von Schacky, Christoph Böttcher, Nicolas Beziere, Reinhard Meier, Y Kosanke, Melanie A. Kimm, Jonathan Vonnemann, Vasilis Ntziachristos, Kai Licha, Jens Dernedde, Sebastian B. Riese, Christian Kuehne, Rainer Haag

Publikováno v: Theranostics
Theranostics 4, 629-641 (2014)

We have synthesized a targeted imaging agent for rheumatoid arthritis based on polysulfated gold nanorods. The CTAB layer on gold nanorods was first replaced with PEG-thiol and then with dendritic polyglycerolsulfate at elevated temperature, which re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5341cf64287cb895bcdb3573a7f72d7
https://pubmed.ncbi.nlm.nih.gov/24723984

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Optoacoustic imaging and staging of inflammation in a murine model of arthritis

Autor: N, Beziere, C, von Schacky, Y, Kosanke, M, Kimm, A, Nunes, K, Licha, M, Aichler, A, Walch, E J, Rummeny, V, Ntziachristos, R, Meier

Publikováno v: Arthritisrheumatology (Hoboken, N.J.). 66(8)

Rheumatoid arthritis (RA) is one of the most frequent inflammatory diseases, causing pain and disability in the affected joints. Early diagnosis is essential for the efficiency of symptom-targeting treatments, but its diagnosis requires careful clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d0b8507b6d74325bbba32ce3d7162e4d
https://pubmed.ncbi.nlm.nih.gov/24692100

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