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Publikováno v:
Progrès en Urologie. 31:78-84
Resume But Les objectifs de ce travail etaient d’evaluer l’impact de l’examen preoperatoire des urines et du caractere infecte des calculs sur la survenue du sepsis urinaire postoperatoire. Materiel et methodes Une etude prospective monocentriq
Publikováno v:
The British Journal of Surgery
Introduction Early during the COVID-19 pandemic, surgeons were advised to use conservative management/open surgery for appendicitis. This single-centre study has explored the resulted management differences. Method Retrospective study covering Prepan
Publikováno v:
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 31(2)
The objectives of this study were to evaluate the impact of preoperative urine culture and the infected nature of stones on the occurrence of postoperative urinary sepsis.A prospective monocentric study included 29 patients operated on for urolithias
Autor:
Salman Y. Jabri, Larry E. Overman
Publikováno v:
The Journal of Organic Chemistry. 78:8766-8788
Evolution of the synthetic strategy that culminated in the first total syntheses of the structurally unique plectosphaeroic acids B (2) and C (3) is described. The successful enantioselective route to (+)-2 and (+)-3 proceeds in 6 and 11 steps from t
Autor:
Choung U. Kim, Sammy Metobo, Haolun Jin, Salman Y. Jabri, Jared W. Evans, Evangelos Aktoudianakis
Publikováno v:
Tetrahedron Letters. 54:6782-6784
We report a study of the influence of Lewis acids upon the regioselectivity of ring opening of quinolinic[2,3]anhydrides to provide 2-(isopropoxycarbonyl)-nicotinic acids. In the presence of stoichiometric amounts of indium trifluoromethanesulfonate
Autor:
Manuel Tsiang, Matthew R. Wright, Choung U. Kim, Salman Y. Jabri, Sammy Metobo, Haolun Jin, Xiaowu Chen, Mish Michael R, Rachael A. Lansdown
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1187-1190
A series of C3 halobenzyl-substituted tricyclic HIV integrase inhibitors was prepared. Improvement in cell-based inhibitor potency was observed in comparison to previously disclosed tricyclic pyrroloquinolines carrying the ‘halobenzyl tail’ at th
Autor:
Choung U. Kim, Richard W. Pastor, Matthew R. Wright, Haolun Jin, Salman Y. Jabri, Peter Pyun, Sammy Metobo, Rachael A. Lansdown, Manuel Tsiang, Ruby Cai, Xiaowu Chen, Mish Michael R
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1388-1391
A series of C5-aza tricyclic HIV integrase inhibitors was prepared. A highly potent and orally bioavailable compound (compound 9) was identified and selected for development.
Autor:
Jared W. Evans, Choung U. Kim, Evangelos Aktoudianakis, Haolun Jin, Salman Y. Jabri, Sammy Metobo
Publikováno v:
ChemInform. 45
We report a study of the influence of Lewis acids upon the regioselectivity of ring opening of quinolinic[2,3]anhydrides to provide 2-(isopropoxycarbonyl)-nicotinic acids. In the presence of stoichiometric amounts of indium trifluoromethanesulfonate
Autor:
Larry E. Overman, Salman Y. Jabri
Publikováno v:
ChemInform. 45