Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.

Autor: C, Chan C, S, Boyce, C, Brideau, S, Charleson, W, Cromlish, D, Ethier, J, Evans, W, Ford-Hutchinson A, J, Forrest M, Y, Gauthier J, R, Gordon, M, Gresser, J, Guay, S, Kargman, B, Kennedy, Y, Leblanc, S, Leger, J, Mancini, P, O'Neill G, M, Ouellet, D, Patrick, D, Percival M, H, Perrier, P, Prasit, I, Rodger

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; August 1999, Vol. 290 Issue: 2 p551-60, 10p