Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Y, Engelborghs"'
Publikováno v:
Toxicology letters. 160(3)
Recent studies indicate that inhaled ultrafine particles can pass into the circulation. To study this translocation in an in vitro model three types of pulmonary epithelial cells were examined. The integrity of the cell monolayer was verified by meas
Publikováno v:
Pharmaceutical research. 18(7)
To evaluate whether fluorescence correlation spectroscopy (FCS) can be used to characterize the complexation between oligonucleotides and cationic polymers.The features of the complexes between rhodamine labeled oligonucleotides (Rh-ONs) and poly(2-d
Autor:
A. Sillen, Y. Engelborghs
Publikováno v:
New Trends in Fluorescence Spectroscopy ISBN: 9783642632143
In the last five years we have studied the time resolved fluorescence of several proteins using multi-frequency phase fluorometry Each protein has taught us new aspects of tryptophan fluorescence and this manuscript describes the accumulated experien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ccc08d628d19e2fd087c1e1b07a5603
https://doi.org/10.1007/978-3-642-56853-4_19
https://doi.org/10.1007/978-3-642-56853-4_19
Autor:
E, Van Craenenbroeck, Y, Engelborghs
Publikováno v:
Journal of molecular recognition : JMR. 13(2)
Fluorescence correlation spectroscopy (FCS) is a fluorescence microscopy technique that allows the study of molecular interactions in extremely low volumes, at nanomolar concentrations, even when binding is not accompanied by a fluorescence change. I
Publikováno v:
The Journal of biological chemistry. 275(34)
We have determined the kinetic scheme and the reaction rates of binding to microtubules of two fluorescent taxoids, 7-O-[N-(4'-fluoresceincarbonyl)-l-alanyl]Taxol (Flutax-1) and 7-O-[N-(2,7-difluoro-4'-fluoresceincarbonyl)-l-alanyl]Taxol (Flutax-2).
Publikováno v:
Journal of biomolecular NMR. 12(4)
Publikováno v:
Proteins. 24(3)
Barnase, the guanine specific ribonuclease of Bacillus amyloliquefaciens, was subjected to mutations in order to alter the electrostatic properties of the enzyme. Ser-85 was mutated into Glu with the goal to introduce an extra charge in the neighborh
Publikováno v:
The Journal of biological chemistry. 268(11)
The mechanism of activation of human plasminogen by recombinant staphylokinase (STAR) was studied using the active site titrant p-nitrophenyl-p'-guanidinobenzoate (NPGB). NPGB prevented active site exposure in equimolar mixtures of plasminogen and ST
Publikováno v:
The Journal of biological chemistry. 268(1)
The kinetics of tropolone methyl ether binding to tubulin were measured by following the loss of colchicine binding capacity upon preincubation of tubulin with tropolone methyl ether. At 25 degrees C a bimolecular association rate constant of 2.7 (+/
Publikováno v:
Molecular pharmacology. 41(1)
The reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is present in virions and infected cells as an heterodimer (p66/p51). A new class of potent and selective HIV-1 inhibitors, the tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepi