Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Y, Amet"'
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 11, Pp 1990-1997 (1999)
Human liver microsomes and recombinant human P450 have been used as enzyme source in order to better understand the requirement for the optimal rate of ω and (ω–1)-hydroxylations of fatty acids by cytochromes P450 2E1 and 4A. Three parameters wer
Externí odkaz:
https://doaj.org/article/8ec8cca2b97b455f9bb57534ea2dfe15
Publikováno v:
Analytica Chimica Acta. 465:193-198
To get a better understanding and knowledge of microsomal cytochrome P450 involvement in the metabolism of fatty acids, e.g. lauric and oleic acids, high performance liquid chromatography (HPLC) was used to resolve the main metabolites. It was couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0949534c2fb3d31623b43be28b38618d
https://doi.org/10.1016/s0003-2670(02)00466-x
https://doi.org/10.1016/s0003-2670(02)00466-x
Publikováno v:
Pathologie Biologie. 49:696-702
Alcohol and xenobiotics share the same oxidative microsomal pathway, which is mainly located in the endoplasmic reticulum of hepatocytes. This pathway involves enzymes that belong to the super family of cytochrome P450 and allows to explain a lot of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c63bb4db40b8a5b272c3b50fef2119a6
https://doi.org/10.1016/s0369-8114(01)00235-8
https://doi.org/10.1016/s0369-8114(01)00235-8
Publikováno v:
European Journal of Nutrition. 39:270-276
Background Long-term ethanol consumption in laboratory animals is associated with histological alterations of liver cells and modifications of fatty acid metabolism. Aim of the study The present study was aimed at investigating the effect of 1- and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84761b49c2711daa577b753ca35cccd6
https://doi.org/10.1007/s003940070006
https://doi.org/10.1007/s003940070006
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 714:133-144
In order to characterize the nature of the active site of cytochrome P450 2E1, the metabolism of various fatty acids with cis/trans geometric configurations has been investigated. A system coupling atmospheric pressure chemical ionization-mass spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2189c2aec0aee7804528d154b1df24c4
https://doi.org/10.1016/s0378-4347(98)00244-8
https://doi.org/10.1016/s0378-4347(98)00244-8
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 681:233-239
The formation of (omega-1)-hydroxylauric acid from lauric acid (LA) can be used as an indicator of the activity of cytochrome P450 2E1 (CYP2E1) in rat and human liver microsomes. A high-performance liquid chromatographic (HPLC) method that is capable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe70a5ed53f9b17a5bcaf85006445fad
https://doi.org/10.1016/0378-4347(96)00043-6
https://doi.org/10.1016/0378-4347(96)00043-6
Publikováno v:
Biochemical and Biophysical Research Communications. 205:269-274
5 alpha-reductase 2 from human prostate solubilized into an active and stable form using a non-ionic detergent octyl glucoside was successfully purified using a four-step chromatographic procedure. The enzyme was obtained as an apparently homogeneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef04cfdd7253c3ab8b83b0fcc1bc18d5
https://doi.org/10.1006/bbrc.1994.2660
https://doi.org/10.1006/bbrc.1994.2660
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 44:133-139
We describe the cloning, sequencing and overexpression of the (3–17)β hydroxysteroid dehydrogenase gene of Pseudomonas testosteroni. A genomic library of Ps. testosteroni total DNA constructed from SauIIIA digests ligated to a λgt11 vector was pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da72845fea887997d9f181502f266c71
https://doi.org/10.1016/0960-0760(93)90020-w
https://doi.org/10.1016/0960-0760(93)90020-w
Publikováno v:
Toxicology letters. 167(3)
The involvement of cytochromes P450 (CYPs) in the oxidation of ethanol into acetaldehyde was investigated by using 16 recombinant human CYP isoforms. Apparent K(m) and V(m) were determined for CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C8, CYP2C9*1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be34aaa0ea12fb2d0548e8e0df8b4cad
https://pubmed.ncbi.nlm.nih.gov/17084997
https://pubmed.ncbi.nlm.nih.gov/17084997
Publikováno v:
Pathologie-biologie. 49(9)
Alcohol and xenobiotics share the same oxidative microsomal pathway, which is mainly located in the endoplasmic reticulum of hepatocytes. This pathway involves enzymes that belong to the super family of cytochrome P450 and allows to explain a lot of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc5a4cb58190f542c3d86d078d193e2d
https://pubmed.ncbi.nlm.nih.gov/11762131
https://pubmed.ncbi.nlm.nih.gov/11762131