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Akademický článek

DDRGK1-mediated ER-phagy attenuates acute kidney injury through ER-stress and apoptosis

Autor: Haijiao Jin, Yuanting Yang, Xuying Zhu, Yin Zhou, Yao Xu, Jialin Li, Chaojun Qi, Xinghua Shao, Jingkui Wu, Shan Wu, Hong Cai, Leyi Gu, Shan Mou, Zhaohui Ni, Shu Li, Qisheng Lin

Publikováno v: Cell Death and Disease, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Acute kidney injury (AKI) constitutes a prevalent clinical syndrome characterized by elevated morbidity and mortality rates, emerging as a significant public health issue. This study investigates the interplay between endoplasmic reticulum (

Externí odkaz: https://doaj.org/article/cab918366598489f9d81c7fd2279bbc4

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Akademický článek

Aquibium pacificus sp. nov., a Novel Mixotrophic Bacterium from Bathypelagic Seawater in the Western Pacific Ocean

Autor: Fan Jiang, Xun Hao, Ding Li, Xuying Zhu, Jiamei Huang, Qiliang Lai, Jianning Wang, Liping Wang, Zongze Shao

Publikováno v: Microorganisms, Vol 12, Iss 8, p 1584 (2024)

A novel Gram-stain-negative, facultatively anaerobic, and mixotrophic bacterium, designated as strain LZ166T, was isolated from the bathypelagic seawater in the western Pacific Ocean. The cells were short rod-shaped, oxidase- and catalase-positive, a

Externí odkaz: https://doaj.org/article/8a06f3ff69a7488293aad91a57f33845

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Akademický článek

HIF1α-BNIP3-mediated mitophagy protects against renal fibrosis by decreasing ROS and inhibiting activation of the NLRP3 inflammasome

Autor: Jialin Li, Qisheng Lin, Xinghua Shao, Shu Li, Xuying Zhu, Jingkui Wu, Shan Mou, Leyi Gu, Qin Wang, Minfang Zhang, Kaiqi Zhang, Jiayue Lu, Zhaohui Ni

Publikováno v: Cell Death and Disease, Vol 14, Iss 3, Pp 1-12 (2023)

Abstract Chronic kidney disease affects approximately 14.3% of people worldwide. Tubulointerstitial fibrosis is the final stage of almost all progressive CKD. To date, the pathogenesis of renal fibrosis remains unclear, and there is a lack of effecti

Externí odkaz: https://doaj.org/article/7f7557f411794a2f8cf93879f8e5b0a9

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Akademický článek

Slower progression of amyotrophic lateral sclerosis with external application of a Chinese herbal plaster–The randomized, placebo-controlled triple-blinded ALS-CHEPLA trial

Autor: Sven Schröder, Mingzhe Wang, Dandan Sima, Joana Schröder, Xuying Zhu, Xuanlu Zheng, Lin Liu, Tingying Li, Qiudong Wang, Thomas Friedemann, Te Liu, Weidong Pan

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

BackgroundAmyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease characterized by gradually increasing damage to the upper and lower motor neurons. However, definitive and efficacious treatment for ALS is not available, and oral i

Externí odkaz: https://doaj.org/article/942525f09b9c45a9b8a7a9f2a2332ec0

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Akademický článek

A Decreased Level of Soluble Klotho Can Predict Cardiovascular Death in No or Mild Abdominal Aortic Calcification Hemodialysis Patients

Autor: Hong Cai, Xuying Zhu, Jiayue Lu, Minxia Zhu, Shang Liu, Yaping Zhan, Zhaohui Ni, Leyi Gu, Weiming Zhang, Shan Mou

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

Background: Soluble Klotho plays an important role in cardiovascular disease and death in chronic kidney disease (CKD). We assessed the relationship between serum soluble Klotho (sKL) level and outcome in MHD patients.Methods: Soluble Klotho was dete

Externí odkaz: https://doaj.org/article/da358f9ef21f4cb8b6116b7f2ca61ef7

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Akademický článek

Periostin Contributes to Immunoglobulin a Nephropathy by Promoting the Proliferation of Mesangial Cells: A Weighted Gene Correlation Network Analysis

Autor: Jingkui Wu, Qisheng Lin, Shu Li, Xinghua Shao, Xuying Zhu, Minfang Zhang, Wenyan Zhou, Zhaohui Ni

Publikováno v: Frontiers in Genetics, Vol 11 (2021)

Immunoglobulin A nephropathy (IgAN) is a known cause of end-stage kidney disease, but the pathogenesis and factors affecting prognosis are not fully understood. In the present study, we carried out weighted gene correlation network analysis (WGCNA) t

Externí odkaz: https://doaj.org/article/90ed22a4c8714349abaef479cbf1dbb6

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