Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Xuri Li"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Endometriosis, a prevalent condition, has long been recognized as a chronic and debilitating ailment affecting an estimated 1790 million women worldwide. Observational studies have established a correlation between endometriosis and ovarian
Externí odkaz:
https://doaj.org/article/46cef9c27d8a41c18702d0a11daa5402
Autor:
Ruiyang Li, Wenben Chen, Mingyuan Li, Ruixin Wang, Lanqin Zhao, Yuanfan Lin, Xinwei Chen, Yuanjun Shang, Xueer Tu, Duoru Lin, Xiaohang Wu, Zhenzhe Lin, Andi Xu, Xun Wang, Dongni Wang, Xulin Zhang, Meimei Dongye, Yunjian Huang, Chuan Chen, Yi Zhu, Chunqiao Liu, Youjin Hu, Ling Zhao, Hong Ouyang, Miaoxin Li, Xuri Li, Haotian Lin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Age is closely related to human health and disease risks. However, chronologically defined age often disagrees with biological age, primarily due to genetic and environmental variables. Identifying effective indicators for biological age in
Externí odkaz:
https://doaj.org/article/ad8b6ca352324c36954f4e8a28baf5b5
Autor:
Chunsik Lee, Rongyuan Chen, Guangli Sun, Xialin Liu, Xianchai Lin, Chang He, Liying Xing, Lixian Liu, Lasse D. Jensen, Anil Kumar, Harald F. Langer, Xiangrong Ren, Jianing Zhang, Lijuan Huang, Xiangke Yin, JongKyong Kim, Juanhua Zhu, Guanqun Huang, Jiani Li, Weiwei Lu, Wei Chen, Juanxi Liu, Jiaxin Hu, Qihang Sun, Weisi Lu, Lekun Fang, Shasha Wang, Haiqing Kuang, Yihan Zhang, Geng Tian, Jia Mi, Bi-Ang Kang, Masashi Narazaki, Aaron Prodeus, Luc Schoonjans, David M. Ornitz, Jean Gariepy, Guy Eelen, Mieke Dewerchin, Yunlong Yang, Jing-Song Ou, Antonio Mora, Jin Yao, Chen Zhao, Yizhi Liu, Peter Carmeliet, Yihai Cao, Xuri Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Although VEGF-B was discovered as a VEGF-A homolog a long time ago, the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups. Notwithstanding, drugs that inhibit VEGF-B together with o
Externí odkaz:
https://doaj.org/article/ad0f2de2f96d45acbb44f158c21c99b6
Autor:
Jianing Zhang, Wanhong Li, Zhen Xiong, Juanhua Zhu, Xiangrong Ren, Shasha Wang, Haiqing Kuang, Xianchai Lin, Antonio Mora, Xuri Li
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2405-2418 (2023)
Platelet-derived growth factor-D (PDGF-D) is abundantly expressed in ocular diseases. Yet, it remains unknown whether and how PDGF-D affects ocular cells or cell-cell interactions in the eye. In this study, using single-cell RNA sequencing (scRNA-seq
Externí odkaz:
https://doaj.org/article/46518d7c96e24950bb4b4761b5dc1970
Autor:
Vincent Geldhof, Laura P. M. H. de Rooij, Liliana Sokol, Jacob Amersfoort, Maxim De Schepper, Katerina Rohlenova, Griet Hoste, Adriaan Vanderstichele, Anne-Marie Delsupehe, Edoardo Isnaldi, Naima Dai, Federico Taverna, Shawez Khan, Anh-Co K. Truong, Laure-Anne Teuwen, François Richard, Lucas Treps, Ann Smeets, Ines Nevelsteen, Birgit Weynand, Stefan Vinckier, Luc Schoonjans, Joanna Kalucka, Christine Desmedt, Patrick Neven, Massimiliano Mazzone, Giuseppe Floris, Kevin Punie, Mieke Dewerchin, Guy Eelen, Hans Wildiers, Xuri Li, Yonglun Luo, Peter Carmeliet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Tumor blood vessels contribute to cancer growth, invasion and metastasis. Here, by using single cell transcriptomics, the authors report an inventory of endothelial cell heterogeneity in patients with breast cancer, including a subtype that expresses
Externí odkaz:
https://doaj.org/article/f607566042124ddc85658b5b9cc9abac
Publikováno v:
MedComm – Future Medicine, Vol 2, Iss 1, Pp n/a-n/a (2023)
Abstract Angiogenesis is the process of new blood vessel growth from pre‐existing ones involving vascular endothelial cell activation, proliferation, migration, and tube formation. The vascular endothelial growth factor A (VEGF‐A) is known to be
Externí odkaz:
https://doaj.org/article/acbef4e388bc44b2a664eab1a7c0a102
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3796-3813 (2022)
This review discusses our current understanding of chromatin biology and bioinformatics under the unifying concept of “chromatin hubs.” The first part reviews the biology of chromatin hubs, including chromatin–chromatin interaction hubs, chroma
Externí odkaz:
https://doaj.org/article/ddc804228bc44bd6bb27f2f1d8282102
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1211 (2023)
Computational prediction of cell-cell interactions (CCIs) is becoming increasingly important for understanding disease development and progression. We present a benchmark study of available CCI prediction tools based on single-cell RNA sequencing (sc
Externí odkaz:
https://doaj.org/article/34e8d8d115a8453197f27b72e2b2e97c
Autor:
Dongyue Lin, Zhonghao Wang, Wei Chen, Tao Shen, Xuan Qiu, Kun Wei, Jiahui Li, Dongsheng Yang, Ping Wang, Xuri Li, Jianhua Yan, Zhongshu Tang
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Amblyopia is a common eye disease characterized by impaired best-corrected visual acuity. It starts in early childhood and leads to permanent vision reduction if left untreated. Even though many young patients with amblyopia are well treated in clini
Externí odkaz:
https://doaj.org/article/bb3c8bd35430428aa83e43eeaa020788
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5874-5887 (2021)
Single-cell RNA sequencing (scRNA-seq) has become a powerful tool for scientists of many research disciplines due to its ability to elucidate the heterogeneous and complex cell-type compositions of different tissues and cell populations. Traditional
Externí odkaz:
https://doaj.org/article/1da729d6270249f2a97801b1a6bb508b