Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xupeng Yue"'
Autor:
Yiqiang Zhou, Yanxin Lu, Xiaolong Wu, Jie Bai, Xupeng Yue, Yifei Liu, Yanling Cai, Xinru Xiao
Publikováno v:
Translational Oncology, Vol 47, Iss , Pp 102046- (2024)
Tumor derived Extracellular vesicles (EVs) in circulating system may contain tumor-specific markers, and EV detection in body fluids could become an important tool for early tumor diagnosis, prognosis assessment. Meningiomas are the most common benig
Externí odkaz:
https://doaj.org/article/0c954f50499346b5b220215c82d3a483
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
This review presents the advancements in nanomaterial (NM)-induced pyroptosis in specific types of cells. We elucidate the relevance of pyroptosis and delineate its mechanisms and classifications. We also retrospectively analyze pyroptosis induced by
Externí odkaz:
https://doaj.org/article/da80ee3f2262425c914b3008a1d004fc
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70300 (2013)
Emerging evidence indicate that microRNAs (miRNAs) may play important roles in cancer. Aberrant expression of miRNAs has been frequently identified in different human malignancies, including colorectal cancer (CRC). However, the mechanism by which de
Externí odkaz:
https://doaj.org/article/3dca418fa41c41af97f18ca02ce239dd
Autor:
Liping Hu, Xupeng Yue, Xin Xu, Xingwei Xu, Huan He, Guowei Gong, Yuting Zhou, Tao Chen, Baohui Qi, Ying Yang
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:2127-2139
A series of novel thiazolidine-4-one urea analogues were designed, synthesized and biologically evaluated. The structure-activity relationship (SAR) at several positions of the scaffolds was investigated and its binding mode was analyzed by molecular
Autor:
Huan He, Xin Xu, Anmian Zhang, Baohui Qi, Guobiao Zhou, Xiaobing Wan, Tao Chen, Xupeng Yue, Ying Yang, Junming Li, Guowei Gong, Yun Hu
Publikováno v:
European Journal of Medicinal Chemistry. 163:10-27
A series of 21 novel N1-(2-aryl-1,3-thiazolidin-4-one)-N3-aryl urea derivatives based on the previously identified lead compound I were synthesized and biologically characterized. The most promising compound 19a was identified as a multi-tyrosine kin
Autor:
Yuting Zhou, Min Liu, Baohui Qi, Fachang Wei, Yuying Chen, Ying Yang, Xupeng Yue, Huan He, Anmian Zhang, Xing Zhou
Publikováno v:
European Journal of Medicinal Chemistry. 146:368-380
A total of 29 novel compounds bearing N1-(2-aryl-1, 3-thiazolidin-4-one)-N3-aryl ureas were designed, synthesized and evaluated for their biological activities. The structure-activity relationships (SARs) and binding modes of this series of compounds
Publikováno v:
Oncology Reports
The dysregulation of microRNAs (miRNAs) is associated with the development and progression of a variety of cancers, including liver cancer. Aberrant expression of miRNA (miR)‑124 has been demonstrated in liver cancer, but its functional mechanism i
Publikováno v:
Bioorganicmedicinal chemistry. 27(17)
Aurora kinases are known to be overexpressed in various solid tumors and implicated in oncogenesis and tumor progression. A series of nicotinamide derivatives were synthesized and their biological activities were evaluated, including kinase inhibitor
Autor:
Chunzhang Yang, Thanh-Truc Huynh, Garima Gupta, Herui Wang, Zhengping Zhuang, Karel Pacak, Abhishek Jha, Emily Y. Chew, Esther Korpershoek, Xupeng Yue, Ying Pang, Richard A Feelders, Eva H. Baker, Aiguo Li
Publikováno v:
Journal of the Endocrine Society
Background: Somatic mutations in hypoxia-inducible factor 2α (HIF2A) is associated with polycythemia-paraganglioma syndrome. Specifically, the classic presentation of female patients with recurrent paragangliomas (PGLs), polycythemia (at birth or in
Autor:
Baohui, Qi, Ying, Yang, Guowei, Gong, Huan, He, Xupeng, Yue, Xin, Xu, Yun, Hu, Junming, Li, Tao, Chen, Xiaobing, Wan, Anmian, Zhang, Guobiao, Zhou
Publikováno v:
European journal of medicinal chemistry. 163
A series of 21 novel N