Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Xunmei Yuan"'
Autor:
Kenichi Kawahori, Yoshitaka Kondo, Xunmei Yuan, Yuki Kawasaki, Nozomi Hanzawa, Kazutaka Tsujimoto, Fumiko Wada, Takashi Kohda, Akihito Ishigami, Tetsuya Yamada, Yoshihiro Ogawa, Koshi Hashimoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/2fc2bac9481e45e88978e3e0e1fc56d6
Autor:
Xunmei Yuan, Kazutaka Tsujimoto, Koshi Hashimoto, Kenichi Kawahori, Nozomi Hanzawa, Miho Hamaguchi, Takami Seki, Makiko Nawa, Tatsuya Ehara, Yohei Kitamura, Izuho Hatada, Morichika Konishi, Nobuyuki Itoh, Yoshimi Nakagawa, Hitoshi Shimano, Takako Takai-Igarashi, Yasutomi Kamei, Yoshihiro Ogawa
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
FGF21 exerts beneficial metabolic effects on multiple tissues. Here the authors show that the Fgf21 gene is demethylated during the postnatal suckling period, creating an epigenetic memory that determines the responsiveness of the Fgf21 gene to induc
Externí odkaz:
https://doaj.org/article/c62f55c79e3144f582a03839a050d571
Autor:
Fumiko Wada, Tetsuya Yamada, Nozomi Hanzawa, Kenichi Kawahori, Yoshitaka Kondo, Koshi Hashimoto, Takashi Kohda, Yuki Kawasaki, Akihito Ishigami, Kazutaka Tsujimoto, Xunmei Yuan, Yoshihiro Ogawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4703a0597d233eaf36ed54ac45dac5b1
https://doaj.org/article/2fc2bac9481e45e88978e3e0e1fc56d6
https://doaj.org/article/2fc2bac9481e45e88978e3e0e1fc56d6
Autor:
Yoshihiro Ogawa, Yutaka Inagaki, Takayoshi Suganami, Sayaka Kanai, Tomomi Hatayama, Shinji Tanaka, Masahiro Asakawa, Xunmei Yuan, Takeru Sakai, Shu Shimada, Katsuhito Fujiu, Ichiro Manabe, Ibuki Shirakawa, Shoji Yamaoka, Yoshimitsu Akiyama, Tetsuya Yamada, Michiko Itoh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Non-alcoholic steatohepatitis (NASH), characterized by chronic inflammation and fibrosis, is predicted to be the leading cause of cirrhosis and hepatocellular carcinoma (HCC) in the next decade. Although recent evidence suggests the importance of fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae1135fa0eb9ae45429b6419d3480be
http://link.springer.com/article/10.1038/s41598-019-56039-0
http://link.springer.com/article/10.1038/s41598-019-56039-0
Autor:
Nozomi Hanzawa, Yoshihiro Ogawa, Tetsuya Yamada, Kenichi Kawahori, Takashi Kohda, Kazutaka Tsujimoto, Yoshitaka Kondo, Akihito Ishigami, Xunmei Yuan, Yuki Kawasaki, Fumiko Wada, Koshi Hashimoto
Publikováno v:
Scientific Reports
Ascorbic acid (AA, vitamin C) serves as a cofactor for ten-eleven translocation (TET) enzymes and induces DNA demethylation in vitro. However, its role in DNA demethylation in vivo remains unclear. We previously reported that DNA demethylation in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47124ac55595475b19632a66a87693f2
https://doi.org/10.1038/s41598-020-77962-7
https://doi.org/10.1038/s41598-020-77962-7
Autor:
Izuho Hatada, Nozomi Hanzawa, Hitoshi Shimano, Yasutomi Kamei, Kenichi Kawahori, Koshi Hashimoto, Tatsuya Ehara, Yoshimi Nakagawa, Makiko Nawa, Nobuyuki Itoh, Xunmei Yuan, Takami Seki, Takako Takai-Igarashi, Miho Hamaguchi, Kazutaka Tsujimoto, Morichika Konishi, Yoshihiro Ogawa, Yohei Kitamura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
The nutritional environment to which animals are exposed in early life can lead to epigenetic changes in the genome that influence the risk of obesity in later life. Here, we demonstrate that the fibroblast growth factor-21 gene (Fgf21) is subject to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a64c7d89dc5ab8466f1cc75347d88e6
http://link.springer.com/article/10.1038/s41467-018-03038-w
http://link.springer.com/article/10.1038/s41467-018-03038-w
Autor:
Tetsuya Yamada, Yoshihiro Ogawa, Izuho Hatada, Kazutaka Tsujimoto, Toshiya Tanaka, Kenichi Kawahori, Miho Hamaguchi, Xunmei Yuan, Yuya Nagaoka, Sumiyo Morita, Nozomi Hanzawa, Koshi Hashimoto, Hiroshi Nishina
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Recently, we reported PPARα-dependent DNA demethylation of the Fgf21 promoter in the postnatal mouse liver, where reduced DNA methylation is associated with enhanced gene expression after PPARα activation. However, there is no direct evidence for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061d7ba99efd317efffd9467a359f098
https://pubmed.ncbi.nlm.nih.gov/32198422
https://pubmed.ncbi.nlm.nih.gov/32198422
Autor:
Saori Kase, Nobuyuki Shibusawa, Masanobu Yamada, Yoshihiro Ogawa, Xunmei Yuan, Kazuhiko Tagawa, Yasuyo Nakajima, Miho Hamaguchi, Kenichi Kawahori, Nozomi Hanzawa, Hitoshi Okazawa, Koshi Hashimoto, Kazutaka Tsujimoto, Kyota Fujita
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 28(3)
Thyroid hormones are essential for normal development of the central nervous system (CNS). Experimental rodents have shown that even a subtle thyroid hormone insufficiency in circulating maternal thyroid hormones during pregnancy may adversely affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393cd7f5b49f6ef6d0b05440edae99b4
https://pubmed.ncbi.nlm.nih.gov/29415629
https://pubmed.ncbi.nlm.nih.gov/29415629
Autor:
Hitoshi Shimano, Kazutaka Tsujimoto, Tatsuya Ehara, Yasutomi Kamei, Mayumi Takahashi, Takashi Tamiya, Takayoshi Suganami, Yoshihiro Ogawa, Izuho Hatada, Erina Tamura, Koshi Hashimoto, Yoshimi Nakagawa, Sayaka Kanai, Xunmei Yuan, Takako Takai-Igarashi
Publikováno v:
Diabetes. 64:775-784
The metabolic function of the liver changes sequentially during early life in mammals to adapt to the marked changes in nutritional environment. Accordingly, hepatic fatty acid β-oxidation is activated after birth to produce energy from breast milk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a37c4673d1b66ffbf344bd297352f1f
https://doi.org/10.2337/db14-0158
https://doi.org/10.2337/db14-0158
Autor:
Yoshihiro Ogawa, Masanobu Kanou, Tomomi Kasahara, Tadahiro Kitamura, Maki Hattori, Yukino Hatazawa, Wouter H. Lamers, Xunmei Yuan, Yasutomi Kamei, Takayoshi Suganami, Sayaka Kanai
Publikováno v:
American journal of physiology. Endocrinology and metabolism, 307(6), E485-E493. American Physiological Society
Skeletal muscle is a reservoir of energy in the form of protein, which is degraded under catabolic conditions, resulting in the formation of amino acids and ammonia as a byproduct. The expression of FOXO1, a forkhead-type transcription factor, increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc6888db968bc0f5f7e8e945ca07ac1
https://doi.org/10.1152/ajpendo.00177.2014
https://doi.org/10.1152/ajpendo.00177.2014