Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Xunlei Kang"'
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
The increasing demand for immune cell applications, both in clinical settings and in research laboratories, has highlighted the critical need for cryopreservation (banking) methods for T cells. While conventional techniques such as freezing with liqu
Externí odkaz:
https://doaj.org/article/54b7cfff0dae4e4b98a76c68052bde78
Autor:
Chen Wang, Ravi Nistala, Min Cao, Yi Pan, Madelaine Behrens, Donald Doll, Richard D. Hammer, Puja Nistala, Hui-Ming Chang, Edward T.H. Yeh, XunLei Kang
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112105- (2023)
Summary: Leukemic-stem-cell-specific targeting may improve the survival of patients with acute myeloid leukemia (AML) by avoiding the ablative effects of standard regimens on normal hematopoiesis. Herein, we perform an unbiased screening of compounds
Externí odkaz:
https://doaj.org/article/4fd2c19656ae473ea08c0f7aeb939853
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Protein tyrosine phosphatases (PTPs) are modulators of cellular functions such as differentiation, metabolism, migration, and survival. PTPs antagonize tyrosine kinases by removing phosphate moieties from molecular signaling residues, thus inhibiting
Externí odkaz:
https://doaj.org/article/93e7526979ac4a5d8f48f3b6e94414b1
Autor:
Li-shu Zhang, Xunlei Kang, Jianming Lu, Yuannyu Zhang, Xiaofeng Wu, Guojin Wu, Junke Zheng, Rubina Tuladhar, Heping Shi, Qiaoling Wang, Lorraine Morlock, Huiyu Yao, Lily Jun-shen Huang, Pascal Maire, James Kim, Noelle Williams, Jian Xu, Chuo Chen, Cheng Cheng Zhang, Lawrence Lum
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 145-158 (2019)
Background: Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenes
Externí odkaz:
https://doaj.org/article/73d06b7f64ea44e7a85caf179ec3fdad
Autor:
Xunlei Kang, Changhao Cui, Chen Wang, Guojin Wu, Heyu Chen, Zhigang Lu, Xiaoli Chen, Li Wang, Jie Huang, Huimin Geng, Meng Zhao, Zhengshan Chen, Markus Müschen, Huan-You Wang, Cheng Cheng Zhang
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background We recently identified the human leukocyte immunoglobulin-like receptor B2 (LILRB2) and its mouse ortholog-paired Ig-like receptor (PirB) as receptors for several angiopoietin-like proteins (Angptls). We also demonstrated that Pir
Externí odkaz:
https://doaj.org/article/bb3ba6dd77ee4554832a15761a81e463
Publikováno v:
Cells, Vol 10, Iss 12, p 3376 (2021)
Acute myeloid leukemia (AML) is a heterogeneous disease associated with various alterations in T cell phenotype and function leading to an abnormal cell population, ultimately leading to immune exhaustion. However, restoration of T cell function allo
Externí odkaz:
https://doaj.org/article/5828f36448074c19b52dc3acfaf99c16
Autor:
Changzheng Li, Binghuo Wu, Yishan Li, Yaxi Liu, Jin Wang, Jiayi Xie, Xi Xu, Xiaobin Tian, Zhitao Ye, Jingjing Guan, Jie Chen, Siyu Xie, Baolin Zhang, Boyong Cai, Qianhao Wang, Haopeng Yu, Tian Lan, Cheuk Him Man, Xunlei Kang, Pengxu Qian, John M. Perry, Aibin He, Linjia Jiang, Meng Zhao
Publikováno v:
Blood. 140:1686-1701
Hematopoietic stem cells (HSCs) have reduced capacities to properly maintain and replenish the hematopoietic system during myelosuppressive injury or aging. Expanding and rejuvenating HSCs for therapeutic purposes has been a long-sought goal with lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4819ee0c1d7fe5aa6fdcb7ebd6ef62e
https://doi.org/10.1182/blood.2022016112
https://doi.org/10.1182/blood.2022016112
Autor:
Zhao-Fu Sheng, Hua Zhang, Jeffery G Phaup, PeiRu Zheng, XunLei Kang, Zhenguo Liu, Hui-Ming Chang, Edward T H Yeh, Alan Kim Johnson, Hui-Lin Pan, De-Pei Li
Publikováno v:
Cardiovascular Research.
Aims Chronic stress is a well-known risk factor for the development of hypertension. However, the underlying mechanisms remain unclear. Corticotropin-releasing hormone (CRH) neurons in the central nucleus of the amygdala (CeA) are involved in the aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d07ef9639d376805b1673d32af693c1a
https://doi.org/10.1093/cvr/cvad056
https://doi.org/10.1093/cvr/cvad056
Autor:
Chen Wang, Ravi Nistala, Min Cao, De-Pei Li, Yi Pan, Mojgan Golzy, Yuqi Cui, Zhenguo Liu, XunLei Kang
Publikováno v:
Arterioscler Thromb Vasc Biol
Background: Hematopoietic stem cell (HSC) therapy has shown promise for tissue regeneration after ischemia. Therefore, there is a need to understand mechanisms underlying endogenous HSCs activation in response to ischemic stress and coordination of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d054f4da6128e9bd02b7e80a070766e2
https://europepmc.org/articles/PMC10037747/
https://europepmc.org/articles/PMC10037747/
Autor:
Hua Zhang, Jing-Jing Zhou, Jian-Ying Shao, Zhao-Fu Sheng, Jingxiong Wang, Peiru Zheng, Xunlei Kang, Zhenguo Liu, Zixi Jack Cheng, Kline, David D., De-Pei Li
Publikováno v:
Journal of Neuroscience; 6/14/2023, Vol. 43 Issue 24, p4513-4524, 12p