Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xun-Ting Zeng"'
Autor:
Tatsuya Oda, Yumiko Natori, Yukie Katayama, Nobukazu Komatsu, Yasuhiro Natori, Kiyotaka Nishikawa, Chisato Yamasaki, Xun-Ting Zeng
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1671:44-50
Shiga toxin (Stx) has an A1-B5 subunit structure, and the A subunit is an RNA N-glycosidase that inhibits cellular protein synthesis. We previously reported that in Caco-2 cells Stx induced cytokines and that the RNA N-glycosidase activity was essent
Autor:
Chiyoko Inagaki, Xun-Ting Zeng, Kyoko Omori, Kaori Kitagawa, Naoki Hattori, Akitsugu Yamamoto, Kyoko Yagyu
Publikováno v:
Biochemical and Biophysical Research Communications. 289:363-371
The Cl(-)-ATPase/pump in the plasma membrane of the rat brain is a candidate for active outwardly directed Cl(-) translocating systems. We recently isolated a Cl(-) pump, 520- or 580-kDa protein complex, which consisted of 51-, 55-, 60-, and 62-kDa p
Autor:
Kyoko Yagyu, Xun-Ting Zeng, Chiyoko Inagaki, Naoki Hattori, Bo Wu, Takao Irie, Kaori Kitagawa
Publikováno v:
Journal of Neurochemistry. 78:569-576
Cl(-)-ATPase in the CNS is a candidate for an outwardly directed neuronal Cl(-) transporter requiring phosphatidylinositol-4-phosphate (PI4P) for its optimal activity. To test its pathophysiological changes in a phosphatidylinositol (PI) metabolism d
Autor:
Xun-Ting Zeng, Koichiro Omori, Toshiaki Higashida, Michiaki Orikasa, Chiyoko Inagaki, Sei Sasaki, Fujio Shimizu, Mitsuyoshi Hara
Publikováno v:
The Japanese Journal of Pharmacology. 83:233-240
In order to demonstrate the localization of an ethacrynic acid-sensitive Cl− pump in the rat kidney, immunohistochemical analysis was performed using an anti-Cl− pump antibody raised against rat brain Cl− pump protein with confocal laser scanni
Autor:
Kaori Kitagawa, Xun-Ting Zeng, Naoki Hattori, Kyoko Omori, Mitsuyoshi Hara, Toshiaki Higashida, Chiyoko Inagaki
Publikováno v:
Neuroscience Letters. 258:85-88
We purified Cl− pump in the rat brain and obtained 520 or 580 kDa protein complexes which consisted of 62, 60, 55 and 51 kDa proteins. An antiserum against 520 kDa protein complex recognized 51 kDa protein in both 520 and 580 kDa complexes, and red
Autor:
Takatoshi Tanabe, Chiyoko Inagaki, Xun-Ting Zeng, Hitomi Otani, Katsuyuki Mishima, Ryoukei Ogawa
Publikováno v:
European Journal of Pharmacology. 321:137-141
Autor:
Xun-Ting Zeng, Hitomi Otani, Takatoshi Tanabe, Ryoukei Ogawa, Katsuyuki Mishima, Chiyoko Inagaki
Publikováno v:
European Journal of Pharmacology. 314:175-183
We examined the mechanisms of the inhibitory effects of calcitonin gene-related peptide (CGRP) on substance-P-induced superoxide anion (O − 2 ) production in human neutrophils. Substance P (30 μM) caused O − 2 production associated with an inosi
Publikováno v:
Brain Research. 641:167-170
Rat brain Cl−-ATPase was solubilized and reconstituted in asolectin liposomes. Phosphatidylinositol-4-monophosphate increased Cl−-ATPase and ATP-dependent Cl− uptake activities in proteoliposomes. The ATP-dependent Cl− uptake was inhibited by
Autor:
Tohru Yasukura, Akio Minato, Sumio Ohnishi, Toshiko Uriu, Takuji Hirose, Xun-Ting Zeng, Kyoko Omori, Chiyoko Inagaki, Masafumi Inoue, Mitsuyoshi Hara
Publikováno v:
Neuroscience Letters. 134:75-78
To investigate the role of Cl(-)-stimulated Mg(2+)-ATPase (Cl(-)-ATPase) in neurons, we examined the effects of ethacrynic acid (0.3 mM), which completely inhibits Cl(-)-ATPase on the intracellular Cl- concentrations of cultured rat hippocampal neuro
Autor:
Toshiko Mikami-Uriu, Kaori Kitagawa, Hitomi Otani, Xun-Ting Zeng, Naoki Hattori, Kyoko Omori, Kyoko Yagyu, Chiyoko Inagaki, Toshiaki Higashida
Publikováno v:
Neuroscience letters. 302(2-3)
Developmental changes in brain Cl(-)-ATPase activity were examined using fetal, neonatal and adult rats. The Cl(-)-ATPase activity rapidly increased over 20 postnatal days to a level four-fold higher than that in an 18-day-old fetus. On Western blot