Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Xun Gui"'
Autor:
Shuang Wang, Junchao Wang, Xiaojuan Yu, Wen Jiang, Shuo Chen, Rongjuan Wang, Mingzhu Wang, Shasha Jiao, Yingying Yang, Wenbo Wang, Huilin Chen, Ben Chen, Chunying Gu, Chuang Liu, An Wang, Min Wang, Gang Li, Cuicui Guo, Datao Liu, Jinchao Zhang, Min Zhang, Lan Wang, Xun Gui
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
By distinguishing between two types of neutralizing antibodies that either exhibit or lack antibody-dependent enhancement (ADE) activity, FcγRIIB and bivalent binding are shown to be required for ADE in SARS-CoV-2 infection.
Externí odkaz:
https://doaj.org/article/1931eb3ad9a74801a89ebf34511f0976
Autor:
Jingjing Xie, Xun Gui, Mi Deng, Heyu Chen, Yuanzhi Chen, Xiaoye Liu, Zhiqiang Ku, Lingxiao Tan, Ryan Huang, Yubo He, Bruce Zhang, Cheryl Lewis, Kenian Chen, Lin Xu, Jian Xu, Tao Huang, X. Charlene Liao, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The current immune checkpoint blockade therapy has been successful in treating some cancers but not others. New molecular targets and therapeutic approaches of cancer immunology need to be identified. Leukocyte associated immunoglobulin like receptor
Externí odkaz:
https://doaj.org/article/6d65a3dbcada490eaa67ace0038064dd
Autor:
Wen Jiang, Zherui Zhang, Yuhe Zhu, Ben Chen, Chunying Gu, Zhiyan Liu, Xukai Zhang, Hualong Xiong, Yanan Zhang, Bin Zheng, Rongjuan Wang, Shasha Jiao, An Wang, Tianying Zhang, Jinchao Zhang, Shuang Wang, Bo Zhang, Gang Li, Xun Gui
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, several variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged and have consistently replaced the previous dominant variant. Therapeutics again
Externí odkaz:
https://doaj.org/article/491b5c95b4854065a43c4ca6afb7e484
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 84-84 (2023)
OBJECTIVES/GOALS: The aims of this study were to: 1) determine the involvement of each Fc gamma receptor isoform in antibody-mediated crosslinking and internalization of LILRB4 in acute monocytic leukemia and 2) elucidate the role of this crosslinkin
Externí odkaz:
https://doaj.org/article/c92afdbbc87a4c31b801fb416b343195
Autor:
Shuang Wang, Yun Peng, Rongjuan Wang, Shasha Jiao, Min Wang, Weijin Huang, Chao Shan, Wen Jiang, Zepeng Li, Chunying Gu, Ben Chen, Xue Hu, Yanfeng Yao, Juan Min, Huajun Zhang, Ying Chen, Ge Gao, Peipei Tang, Gang Li, An Wang, Lan Wang, Jinchao Zhang, Shuo Chen, Xun Gui, Zhiming Yuan, Datao Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Here the authors characterize a monoclonal antibody from a COVID-19 convalescent patient that interferes with SARS-CoV-2 spike binding to ACE2 and has prophylactic and therapeutic activity in non-human primates. Antibody-dependent enhancement of infe
Externí odkaz:
https://doaj.org/article/64fd62f6fe674572808f71c3eaca2ed9
Autor:
Zhiran Shen, He Zhu, Jiyu Hong, Xun Gui, Heyuan Guan, Jiangli Dong, Hanguang Li, Xiaoli Wang, Wentao Qiu, Enze Zhang, Yunyao Ou, Dongqin Lu, Luqi Luo, Huihui Lu, Wenguo Zhu, Jianhui Yu, Yunhan Luo, Zhe Chen, Gangding Peng
Publikováno v:
Nanoscale Research Letters, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract The tungsten diselenide (WSe2) has attracted considerable interest owing to their versatile applications, such as p-n junctions, transistors, fiber lasers, spintronics, and conversion of solar energy into electricity. We demonstrate all-opti
Externí odkaz:
https://doaj.org/article/7fea0cc18947437c82b92d647898cd66
Autor:
Tao Huang, An Song, Ryan Stafford, Maria Jose Costa, Jing-Tyan Ma, Krista McCutcheon, Heyu Chen, Kyu Hong, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang, X Charlene Liao, Caroline Bonnans, Azita Tabrizi, Jingjing Xie, Hongyu Tian, Xun Gui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/32c0a8d9110944f2aca679ae4d4aa3f6
Autor:
Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju
Publikováno v:
eLife, Vol 10 (2021)
Background: Hepatic platelet accumulation contributes to acetaminophen (APAP)-induced liver injury (AILI). However, little is known about the molecular pathways involved in platelet recruitment to the liver and whether targeting such pathways could a
Externí odkaz:
https://doaj.org/article/87bb9242be7e4ea1a0cab9c6806e6563
Autor:
Wen Jiang, Junchao Wang, Shasha Jiao, Chenjian Gu, Wei Xu, Ben Chen, Rongjuan Wang, Huilin Chen, Youhua Xie, An Wang, Gang Li, Dadi Zeng, Jinchao Zhang, Min Zhang, Shuang Wang, Mingzhu Wang, Xun Gui
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The global pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in widespread social and economic disruption. Effective interventions are urgently needed for the prevention and treatment of COVID-19
Externí odkaz:
https://doaj.org/article/18d5362b079c44e38318bbde4ed0ea84
Autor:
Yasuaki Anami, Chisato M. Yamazaki, Wei Xiong, Xun Gui, Ningyan Zhang, Zhiqiang An, Kyoji Tsuchikama
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The valine-citrulline dipeptide, which is used as a cleavable linker for antibody-drug conjugates, is instable in mouse plasma. Here, the authors developed a glutamic acid–valine–citrulline tripeptide sequence as a stable alternative that still i
Externí odkaz:
https://doaj.org/article/8436b2df5ee445a5b2278b4b789128d3