Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Xuling Zhu"'
Autor:
Yanjie Yao, Erhui Xiong, Xuelian Qu, Junfeng Li, Hongli Liu, Leipo Quan, Wenyan Lu, Xuling Zhu, Meiling Chen, Ke Li, Xiaoming Chen, Yun Lian, Weiguo Lu, Dan Zhang, Xinan Zhou, Shanshan Chu, Yongqing Jiao
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Soybean is one of the most important oil crops in the world. The domestication of wild soybean has resulted in significant changes in the seed oil content and seed size of cultivated soybeans. To better understand the molecular me
Externí odkaz:
https://doaj.org/article/ff13f50fb9a54d0a8a6d1635a4656974
Autor:
Suhail Khoja, Xiao-Bo Liu, Brian Truong, Matthew Nitzahn, Jenna Lambert, Adam Eliav, Eram Nasser, Emma Randolph, Kristine E. Burke, Rebecca White, Xuling Zhu, Paolo G.V. Martini, Itzhak Nissim, Stephen D. Cederbaum, Gerald S. Lipshutz
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 859-874 (2022)
Arginase deficiency is associated with prominent neuromotor features, including spastic diplegia, clonus, and hyperreflexia; intellectual disability and progressive neurological decline are other signs. In a constitutive murine model, we recently des
Externí odkaz:
https://doaj.org/article/27c6ab38d6da42bdbac80e2bb9c3a868
Autor:
Shanshan Chu, Hui Ma, Ke Li, Junfeng Li, Hongli Liu, Leipo Quan, Xuling Zhu, Meiling Chen, Wenyan Lu, Xiaoming Chen, Xuelian Qu, Jiaqi Xu, Yun Lian, Weiguo Lu, Erhui Xiong, Yongqing Jiao
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Soybean cyst nematode (SCN) is a serious damaging disease in soybean worldwide. Peking- and PI 88788-type sources of resistance are two most important germplasm used in breeding resistant soybean cultivars against this disease. However, until now, no
Externí odkaz:
https://doaj.org/article/988574ae625245cc8987573008996567
Autor:
Lei Jiang, Ji-Sun Park, Ling Yin, Rodrigo Laureano, Eric Jacquinet, Jinsong Yang, Shi Liang, Andrea Frassetto, Jenny Zhuo, Xinhua Yan, Xuling Zhu, Steven Fortucci, Kara Hoar, Cosmin Mihai, Christopher Tunkey, Vlad Presnyak, Kerry E. Benenato, Christine M. Lukacs, Paolo G. V. Martini, Lin T. Guey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Propionic acidemia is a serious pediatric inherited disorder with no effective treatments. Here the authors demonstrate that delivering dual mRNAs as an enzyme replacement approach can be used as an effective therapy in a mouse model of propionic aci
Externí odkaz:
https://doaj.org/article/c8fd3846b2b840c782c81abf4afb2075
Autor:
Ding An, Jessica L. Schneller, Andrea Frassetto, Shi Liang, Xuling Zhu, Ji-Sun Park, Matt Theisen, Sue-Jean Hong, Jenny Zhou, Raj Rajendran, Becca Levy, Rebecca Howell, Gilles Besin, Vladimir Presnyak, Staci Sabnis, Kerry E. Murphy-Benenato, E. Sathyajith Kumarasinghe, Timothy Salerno, Cosmin Mihai, Christine M. Lukacs, Randy J. Chandler, Lin T. Guey, Charles P. Venditti, Paolo G.V. Martini
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3548-3558 (2017)
Summary: Isolated methylmalonic acidemia/aciduria (MMA) is a devastating metabolic disorder with poor outcomes despite current medical treatments. Like other mitochondrial enzymopathies, enzyme replacement therapy (ERT) is not available, and although
Externí odkaz:
https://doaj.org/article/48a6dc8892224dcc94c4537810ade1f9
Autor:
Gerald S. Lipshutz, Gabriella Allegri, Xiao-Bo Liu, Kristine Burke, Xuling Zhu, Stephen D. Cederbaum, Johannes Häberle, Paolo Martini, Brian Truong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 42
Arginase deficiency is caused by biallelic mutations in arginase 1 (ARG1), the final step of the urea cycle, and results biochemically in hyperargininemia and the presence of guanidino compounds, while it is clinically notable for developmental delay
Autor:
Matt Theisen, Jaclyn Milton, Becca Levy, Ling Yin, Andrea Frassetto, Staci Sabnis, Vladimir Presnyak, Gilles Besin, Kerry Benenato, Timothy Salerno, Kristin E. Burke, Andy Lynn, Paolo Martini, Xuling Zhu, Patrick Finn, Christine Lukacs, Lin T. Guey, Summar Siddiqui, Jenny Zhuo, Joe Milano
Publikováno v:
The American Journal of Human Genetics. 104:625-637
Fabry disease is an X-linked lysosomal storage disease caused by loss of alpha galactosidase A (α-Gal A) activity and is characterized by progressive accumulation of globotriaosylceramide and its analogs in all cells and tissues. Although enzyme rep
Autor:
Christopher Tunkey, Xinhua Yan, Cosmin Mihai, Ling Yin, Andrea Frassetto, Shi Liang, Lei Jiang, Jenny Zhuo, Xuling Zhu, Steven##Fortucci, Kara Hoar, Paolo Martini, Rodrigo Laureano, Christine Lukacs, Kerry Benenato, Vladimir Presnyak, Ji Sun Park, Lin T. Guey, Eric Jacquinet, Jinsong Yang
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Propionic acidemia/aciduria (PA) is an ultra-rare, life-threatening, inherited metabolic disorder caused by deficiency of the mitochondrial enzyme, propionyl-CoA carboxylase (PCC) composed of six alpha (PCCA) and six beta (PCCB) subunits. We herein r
Publikováno v:
Journal of food protection. 84(1)
In order to reduce the health risks associated with red meat as listed by the World Health Organization, the work presented in this article aimed to elucidate the interaction between 5'-CMP-supplemented feed and N-glycolylneuraminic acid (Neu5Gc) in
Autor:
Greg Nowak, Xuling Zhu, Marianne Eybye, Lisa M. Rice, Ahmad Karadagi, Andrea Frassetto, Ewa Ellis, Paolo Martini, Alex G. Cavedon, Helen Zemack, Stephen C. Strom, Rebecca A. White, Eleonora Guadagnin, Carl Jorns
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Alpha 1-antitrypsin (AAT) deficiency arises from an inherited mutation in the SERPINA1 gene. The disease causes damage in the liver where the majority of the AAT protein is produced. Lack of functioning circulating AAT protein also causes uninhibited