Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xuling Xue"'
Autor:
Jiong‐sheng Hu, Chenwen Shao, Xueao Wang, Xiaojiao Di, Xuling Xue, Zhi Su, Jing Zhao, Hai‐Liang Zhu, Hong‐Ke Liu, Yong Qian
Publikováno v:
Advanced Science, Vol 6, Iss 15, Pp n/a-n/a (2019)
Abstract Epilepsy is a chronic neurodegenerative disease, and accumulating evidence suggests its pathological progression is closely associated with peroxynitrite (ONOO−). However, understanding the function remains challenging due to a lack of in
Externí odkaz:
https://doaj.org/article/674b500fa74c49e39a732f106ce1e9ac
Autor:
Yuanlei Huang, Mengdi Lv, Binglian Guo, Guojing Hu, Yong Qian, Zhi Su, Xuling Xue, Hong-Ke Liu
Publikováno v:
Dalton Transactions. 52:6922-6933
In this work, we found that MA-bpy-Ru show high cytotoxicity to MCF-7 cells. It can increase ROS, decrease MMP, induce apoptosis and eventually autophagy. It also inhibits the expression of COX-2 and PGE2, which may help activate antitumor immunity.
Autor:
Guojing Hu, Mengdi Lv, Binglian Guo, Yuanlei Huang, Zhi Su, Yong Qian, Xuling Xue, Hong-Ke Liu
Publikováno v:
Journal of Inorganic Biochemistry. 243:112195
Autor:
Mengdi Lv, Xiaoting Qian, Shijie Li, Jie Gong, Qun Wang, Yong Qian, Zhi Su, Xuling Xue, Hong-Ke Liu
Publikováno v:
Journal of Inorganic Biochemistry. 238:112057
It is a major challenge to design novel multifunctional metal-based chemotherapeutic agents for anti-tumor and anti-metastasis applications. Two complexes (OA-Ir and OA-Ru) were synthesized via CuAAC (copper-catalyzed azide-alkyne cycloaddition) reac
Publikováno v:
Biomaterials Science. 8:3994-4002
Besides tumor hypoxia and limitation of superficial lesions, the short lifetime of photoinduced reactive oxygen species (ROS) is another factor repressing photodynamic therapy (PDT) efficacy. To overcome these problems, this study developed newly des
Autor:
Lu, Liu, Jun, Chen, Meng-Meng, Wang, Yuanlei, Huang, Yong, Qian, Xuling, Xue, Zhi, Su, Hong-Ke, Liu
Publikováno v:
Journal of Inorganic Biochemistry. 235:111913
9-Anthracenecarboxylic acid (9-Ac) was reported early as a chloride channel inhibitor and was found to exhibit significant anti-proliferative activity on leukemic cells, but has not been researched in solid tumor cells. Herein, a 9-anthraceneic acid
Autor:
Xuling Xue, Chenggen Qian, Hongbao Fang, Hong‐Ke Liu, Hao Yuan, Zijian Guo, Yang Bai, Weijiang He
Publikováno v:
Angewandte Chemie. 131:12791-12796
Autor:
Martin J. Paterson, Kirill A. Lomachenko, Abraha Habtemariam, Yong Qian, Zong-Wan Mao, Hao Yuanyuan, Claudio Garino, Ling-Feng He, Liang He, Luca Salassa, Russell J. Needham, Zhi Su, Xuling Xue, Ying Fu, Hong-Ke Liu, Clément Soulié, Madeleine J. Koh, Peter J. Sadler
Half-sandwich Os-arene complexes exhibit promising anticancer activity, but their photochemistry has hardly been explored. To exploit the photocytotoxicity and photochemistry of Os-arenes, O,O-chelated complexes [Os(η6-p-cymene)(Curc)Cl] (OsCUR-1, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357ff6d993a2346ba028afb9e5764fbf
http://hdl.handle.net/2318/1823827
http://hdl.handle.net/2318/1823827
Autor:
Mengdi Lv, Chenggen Qian, Jing Zhao, Jingwen Dong, Qin Tao, Zijian Guo, Zhi Su, Xuling Xue, Yong Qian, Hong-Ke Liu, Yuanxin Dai
Publikováno v:
National Science Review
Synthetic lethality was proposed nearly a century ago by geneticists and recently applied to develop precision anti-cancer therapies. To exploit the synthetic lethality concept in the design of chemical anti-cancer agents, we developed a bio-orthogon
Publikováno v:
Biomaterials science. 8(14)
Besides tumor hypoxia and limitation of superficial lesions, the short lifetime of photoinduced reactive oxygen species (ROS) is another factor repressing photodynamic therapy (PDT) efficacy. To overcome these problems, this study developed newly des