Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Xukun Bi"'
Autor:
Xukun Bi, Xiaotian Wu, Jiaqi Chen, Xiaoting Li, Yangjun Lin, Yingying Yu, Xuexian Fang, Xihao Cheng, Zhaoxian Cai, Tingting Jin, Shuxian Han, Meihui Wang, Peidong Han, Junxia Min, Guosheng Fu, Fudi Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Pressure overload–induced cardiac hypertrophy is a common cause of heart failure (HF), and emerging evidence suggests that excessive oxidized lipids have a detrimental effect on cardiomyocytes. However, the key regulator of lipid toxicity
Externí odkaz:
https://doaj.org/article/e07f4a62ce18479dbfd9ef02a1303ebb
Publikováno v:
Metabolites, Vol 14, Iss 6, p 294 (2024)
Cardiovascular diseases are the most common causes of mortality and disability worldwide. Eicosanoids are a group of bioactive metabolites that are mainly oxidized by arachidonic acid. Eicosanoids play a diverse role in cardiovascular diseases, with
Externí odkaz:
https://doaj.org/article/3eb1fefd2b7a4350aa2822c89c23624a
Autor:
Liding Zhao, Ya Li, Tian Xu, Qingbo Lv, Xukun Bi, Xianglan Liu, Guosheng Fu, Yunzeng Zou, Junbo Ge, Zhaoyang Chen, Wenbin Zhang
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-17 (2022)
Abstract Background The unique mechanism of diabetic atherosclerosis has been a central research focus. Previous literature has reported that the inflammatory response mediated by dendritic cells (DCs) plays a vital role in the progression of atheros
Externí odkaz:
https://doaj.org/article/08a052c846a8409e8570fdec485616cc
Autor:
Xiaoting Li, Xukun Bi
Publikováno v:
Metabolites, Vol 13, Iss 5, p 615 (2023)
Disrupted fatty acid metabolism is one of the most important metabolic features in heart failure. The heart obtains energy from fatty acids via oxidation. However, heart failure results in markedly decreased fatty acid oxidation and is accompanied by
Externí odkaz:
https://doaj.org/article/5673aa26618741cc8289cd6f7fcef6ba
Autor:
Tingting Jin, Jun Lin, Yingchao Gong, Xukun Bi, Shasha Hu, Qingbo Lv, Jiaweng Chen, Xiaoting Li, Jiaqi Chen, Wenbin Zhang, Meihui Wang, Guosheng Fu
Publikováno v:
Cells, Vol 10, Iss 6, p 1446 (2021)
Both calcium-independent phospholipase A2 beta (iPLA2β) and endoplasmic reticulum (ER) stress regulate important pathophysiological processes including inflammation, calcium homeostasis and apoptosis. However, their roles in ischemic heart disease a
Externí odkaz:
https://doaj.org/article/023c908438c945ffb7bf1b6d77c13e8c
Autor:
Jiaqi Chen, Meihui Wang, Jiaweng Chen, Jun Lin, Yingchao Gong, Shasha Hu, Guosheng Fu, Xukun Bi, Tingting Jin, Wenbin Zhang, Qingbo Lv, Xiaoting Li
Publikováno v:
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1446, p 1446 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1446, p 1446 (2021)
Both calcium-independent phospholipase A2 beta (iPLA2β) and endoplasmic reticulum (ER) stress regulate important pathophysiological processes including inflammation, calcium homeostasis and apoptosis. However, their roles in ischemic heart disease a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a00b19cbe2ca3f3d0e408a69ab6167b
Autor:
Xiaoting Li, Ali A. Al-Hashimi, Chau Yt Nguyen, Zhao V. Wang, Herman I. May, Thomas G. Gillette, Joseph A. Hill, Guangyu Zhang, Xukun Bi, Guo Sheng Fu, Richard C. Austin, Xiaoding Wang
Publikováno v:
Circulation Research. 122:1545-1554
Rationale: Restoration of coronary artery blood flow is the most effective means of ameliorating myocardial damage triggered by ischemic heart disease. However, coronary reperfusion elicits an increment of additional injury to the myocardium. Accumul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76fe8579ed80290b2d38360062bb8436
https://doi.org/10.1161/circresaha.117.312641
https://doi.org/10.1161/circresaha.117.312641
Autor:
Philipp E. Scherer, Guosheng Fu, Xukun Bi, Xiaoding Wang, Anwarul Ferdous, Zhao V. Wang, Guangyu Zhang, Lin Xu, Thomas G. Gillette, Amy S. Lee, Xiang Luo, Yingfeng Deng, Xuejun Jiang
Publikováno v:
Cell Death and Differentiation
Secretory and transmembrane proteins rely on proper function of the secretory pathway for folding, posttranslational modification, assembly, and secretion. Accumulation of misfolded proteins in the endoplasmic reticulum (ER) stimulates the unfolded p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d65328792248b061d3239bf260aa14
http://europepmc.org/articles/PMC6261960
http://europepmc.org/articles/PMC6261960
Autor:
Zhida Shen, Meihui Wang, Guosheng Fu, Xukun Bi, Qi Chen, Zetao Ma, Hangying Ying, Dongwu Lai, Yanbo Zhao, Chongying Jin, Xiaoting Li
Publikováno v:
Experimental and Therapeutic Medicine
Type 2 diabetes mellitus (DM) is a metabolic disease with worldwide prevalence that is associated with a decrease in the number and function of endothelial progenitor cells (EPCs). The aim of the present study was to explore the potential hub genes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27aee8076afd651cffba2afd73c23747
https://doi.org/10.3892/etm.2019.8239
https://doi.org/10.3892/etm.2019.8239
Autor:
Richard C. Austin, Chao Li, Thomas G. Gillette, Guangyu Zhang, Ali Al-Hashimi, Xiang Luo, Xukun Bi, Yingfeng Deng, Yanggan Wang, Xiaoding Wang, Zhao V. Wang
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 73(2)
The heart manifests hypertrophic growth in response to elevation of afterload pressure. Cardiac myocyte growth involves new protein synthesis and membrane expansion, of which a number of cellular quality control machineries are stimulated to maintain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4601572f130082cbae2d52a4bd1d7833
https://pubmed.ncbi.nlm.nih.gov/30580686
https://pubmed.ncbi.nlm.nih.gov/30580686