Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Xujun Liang"'
Autor:
Longying Jiang, Xueke Liu, Xujun Liang, Shuyan Dai, Hudie Wei, Ming Guo, Zhuchu Chen, Desheng Xiao, Yongheng Chen
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3149-3157 (2023)
Farnesoid X receptor (FXR) is a ligand-activated transcription factor known as bile acid receptor (BAR). FXR plays critical roles in various biological processes, including metabolism, immune inflammation, liver regeneration and liver carcinogenesis.
Externí odkaz:
https://doaj.org/article/80ddc1f6a1324d7cb9b5b406ba605ae2
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Gelsolin-like capping actin protein (CapG) modulates actin dynamics and actin-based motility with a debatable role in tumorigenic progression. The motility-associated functions and potential molecular mechanisms of CapG in nasopha
Externí odkaz:
https://doaj.org/article/e9e1b1144ee24ac1824503934585145f
Autor:
Jin Jin, Xujun Liang, Wu Bi, Ruijie Liu, Sai Zhang, Yi He, Qingming Xie, Shilei Liu, Ji-Chang Xiao, Pengfei Zhang
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1705 (2023)
Fenofibrate is known as a lipid-lowering drug. Although previous studies have reported that fenofibrate exhibits potential antitumor activities, IC50 values of fenofibrate could be as high as 200 μM. Therefore, we investigated the antitumor activiti
Externí odkaz:
https://doaj.org/article/bea5f165f9a145df97adca402ea5ac7c
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Colon adenocarcinoma (COAD) is one of the most common malignant tumors and is diagnosed at an advanced stage with a poor prognosis worldwide. Pyroptosis is involved in the initiation and progression of tumors. This research focuse
Externí odkaz:
https://doaj.org/article/f7ba10ae37114ffd9f61dc69f47fee96
Publikováno v:
Buildings, Vol 13, Iss 10, p 2557 (2023)
During the Qing Dynasty and Republic of China, Three Essentials of Dwelling was a much-sought-after approach for the design of quadrangle dwellings, with the primary focus being on the positioning of the doorways. By employing vector data of typical
Externí odkaz:
https://doaj.org/article/0820073ffaea4c24bf60283676720bf1
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 644 (2023)
Background: Hepatocellular carcinoma (HCC) is a malignant tumor associated with high morbidity and mortality. Therefore, it is of great importance to develop effective prognostic models and guide clinical treatment in HCC. Protein lactylation is foun
Externí odkaz:
https://doaj.org/article/92f0b005b83d44c697312fef020c73cc
Autor:
Liuying Zhou, Ruijie Liu, Xujun Liang, Sai Zhang, Wu Bi, Mei Yang, Yi He, Jin Jin, Shisheng Li, Xinming Yang, Junjiang Fu, Pengfei Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 1025-1039 (2020)
Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in southern China and southeast Asia. Emerging evidence revealed that long noncoding RNAs (lncRNAs) might play important roles in the development and progression of many cancer
Externí odkaz:
https://doaj.org/article/872655164e614eb9bc23a9dd6b28c3f7
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-17 (2019)
Abstract The problem of drug side effects is one of the most crucial issues in pharmacological development. As there are many limitations in current experimental and clinical methods for detecting side effects, a lot of computational algorithms have
Externí odkaz:
https://doaj.org/article/2b27b071ee4547b695bbc3b5d6f5187d
Autor:
Huichao Huang, Fangling Huang, Xujun Liang, Ying Fu, Zhe Cheng, Yan Huang, Zhuchu Chen, Yankun Duan, Yongheng Chen
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 37 (2022)
Background: Afatinib, a second-generation tyrosine kinase inhibitor (TKI), exerts its radiosensitive effects in nasopharyngeal carcinoma (NPC). However, the detailed mechanism of afatinib-mediated sensitivity to radiation is still obscure in NPC. Met
Externí odkaz:
https://doaj.org/article/b6ec1e042935410e8d61e115b59f901e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Distant metastasis is a major cause of treatment failure in nasopharyngeal carcinoma (NPC) patients. Cell surface proteins represent attractive targets for cancer diagnosis or therapy. However, the cell surface proteins associated with NPC metastasis
Externí odkaz:
https://doaj.org/article/5a93a7bf42f74164b053be12c3224835