Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Xujie Zhao"'
Autor:
Tongfeng Liu, Shuwen Cheng, Bo Peng, Haojing Zang, Xiaofeng Zhu, Xuetong Wang, Xujie Zhao, Yinmin Gu, Yongbo Pan, Hongbo Hu, Shan Gao
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-9 (2024)
Abstract The function of PD-1/PD-L1 axis have been intensively studied for immune escape of various cancers. However, the underlying function of PD-L2 remains poorly understood. Here, we demonstrate that PD-L2 is majorly expressed in exosomes with su
Externí odkaz:
https://doaj.org/article/2ba262f06039479597085c95c86298af
Autor:
Xuetong Wang, Tongfeng Liu, Yifei Li, Ao Ding, Chang Zhang, Yinmin Gu, Xujie Zhao, Shuwen Cheng, Tianyou Cheng, Songzhe Wu, Liqiang Duan, Jihang Zhang, Rong Yin, Man Shang, Shan Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The immune checkpoint receptor, programmed cell death 1 (PD-1, encoded by PDCD1), mediates the immune escape of cancer, but whether PD-1 splicing isoforms contribute to this process is still unclear. Here, we identify an alternative splicing
Externí odkaz:
https://doaj.org/article/fc5cd10ef1a74250b0815e02efc62d7d
Autor:
Shaela Wright, Xujie Zhao, Wojciech Rosikiewicz, Shelby Mryncza, Judith Hyle, Wenjie Qi, Zhenling Liu, Siqi Yi, Yong Cheng, Beisi Xu, Chunliang Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Accumulating evidence indicates that HOXA9 dysregulation is necessary and sufficient for leukemic transformation and maintenance. However, it remains largely unknown how HOXA9, as a homeobox transcriptional factor, binds to noncoding regulat
Externí odkaz:
https://doaj.org/article/471e2ddbee5c446b898b4a5cbf5a07c6
Autor:
Xujie Zhao, Ping Wang, Jonathan D. Diedrich, Brandon Smart, Noemi Reyes, Satoshi Yoshimura, Jingliao Zhang, Wentao Yang, Kelly Barnett, Beisi Xu, Zhenhua Li, Xin Huang, Jiyang Yu, Kristine Crews, Allen Eng Juh Yeoh, Marina Konopleva, Chia-Lin Wei, Ching-Hon Pui, Daniel Savic, Jun J. Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Different molecular subtypes defined by specific gene rearrangements have been described for acute lymphoblastic leukaemia (ALL). Here, the authors show that ZNF384 fusion activates FLT3 expression conferring a therapeutic vulnerability for ZNF384- r
Externí odkaz:
https://doaj.org/article/d14b4f6c096c49f694347dc01d940e14
Publikováno v:
Chinese Journal of Population, Resources and Environment, Vol 20, Iss 2, Pp 115-124 (2022)
The carbon market auction mechanism is an important policy tool for carbon pricing and a key mechanism that supports carbon emission neutralization, especially for China. A few systematic studies exist on China’s carbon market auction mechanism. Th
Externí odkaz:
https://doaj.org/article/623470be212d4a66bcd54a826fbb7963
Autor:
Rina Nishii, Takanori Mizuno, Daniel Rehling, Colton Smith, Brandi L. Clark, Xujie Zhao, Scott A. Brown, Brandon Smart, Takaya Moriyama, Yuji Yamada, Tatsuo Ichinohe, Makoto Onizuka, Yoshiko Atsuta, Lei Yang, Wenjian Yang, Paul G. Thomas, Pål Stenmark, Motohiro Kato, Jun J. Yang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nucleoside analogs (NNA), such as acyclovir (ACV) and ganciclovir (GCV), are widely used as anti-virals to treat herpes virus infection. Here, Nishii et al. show that diphosphatase NUDT15 hydrolyzes ACV and GCV, therewith reducing NNA activity in vit
Externí odkaz:
https://doaj.org/article/ac367d8e92bf4e2bb684ff635f13452f
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
There is growing evidence for an inherited basis of susceptibility to childhood acute lymphoblastic leukemia. Genomewide association studies by us and others have identified non-coding acute lymphoblastic leukemia risk variants at the ARID5B gene loc
Externí odkaz:
https://doaj.org/article/578d34f1acb9404ead9c0d419cc35eab
Autor:
Hao Zhang, Yang Zhang, Xinyue Zhou, Shaela Wright, Judith Hyle, Lianzhong Zhao, Jie An, Xujie Zhao, Ying Shao, Beisi Xu, Hyeong-Min Lee, Taosheng Chen, Yang Zhou, Xiang Chen, Rui Lu, Chunliang Li
Publikováno v:
eLife, Vol 9 (2020)
Aberrant HOXA9 expression is a hallmark of most aggressive acute leukemias, notably those with KMT2A (MLL) gene rearrangements. HOXA9 overexpression not only predicts poor diagnosis and outcome but also plays a critical role in leukemia transformatio
Externí odkaz:
https://doaj.org/article/c05bb78898d24b23a12ae92b7e92ebae
Publikováno v:
Haematologica, Vol 108, Iss 10 (2020)
Externí odkaz:
https://doaj.org/article/611746533d734b0888712519474e10a7
Publikováno v:
Discrete Dynamics in Nature and Society, Vol 2020 (2020)
Financial extreme jumps in asset price may propagate across stock markets and lead to the market-wide crashes, which severely threatens the stability of the financial system. In order to analyzing the contagion features of jump tail risk, this paper
Externí odkaz:
https://doaj.org/article/4f9a7751e08a4f82b9133c6f06114766