Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Xujia Wu"'
Autor:
Jian Zhong, Xujia Wu, Yixin Gao, Junju Chen, Maolei Zhang, Huangkai Zhou, Jia Yang, Feizhe Xiao, Xuesong Yang, Nunu Huang, Haoyue Qi, Xiuxing Wang, Fan Bai, Yu Shi, Nu Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Activated by its single ligand, hepatocyte growth factor (HGF), the receptor tyrosine kinase MET is pivotal in promoting glioblastoma (GBM) stem cell self-renewal, invasiveness and tumorigenicity. Nevertheless, HGF/MET-targeted therapy has s
Externí odkaz:
https://doaj.org/article/3b970997fc734d1a87a1dd27f3c4325c
Autor:
Jian Zhong, Xuesong Yang, Junju Chen, Kejun He, Xinya Gao, Xujia Wu, Maolei Zhang, Huangkai Zhou, Feizhe Xiao, Lele An, Xiuxing Wang, Yu Shi, Nu Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Glioblastoma (GBM) is a highly aggressive brain tumor, frequently resistant to therapies, including natural killer (NK) cell based immunotherapy. Here, the authors show that the circular RNA EZH2 is highly expressed in GBM and encodes the peptide EZH
Externí odkaz:
https://doaj.org/article/7adce4b736e248b8ab7659ba7c19b129
Autor:
Xin Xia, Xixi Li, Fanying Li, Xujia Wu, Maolei Zhang, Huangkai Zhou, Nunu Huang, Xuesong Yang, Feizhe Xiao, Dawei Liu, Lixuan Yang, Nu Zhang
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/407b5186d14649f5809d2d35b858f454
Autor:
Derrick Lee, Ryan C. Gimple, Xujia Wu, Briana C. Prager, Zhixin Qiu, Qiulian Wu, Vikas Daggubati, Aruljothi Mariappan, Jay Gopalakrishnan, Matthew R. Sarkisian, David R. Raleigh, Jeremy N. Rich
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Glioblastoma ranks among the most aggressive and lethal of all human cancers. Self-renewing, highly tumorigenic glioblastoma stem cells (GSCs) contribute to therapeutic resistance and maintain cellular heterogeneity. Here, we interrogated superenhanc
Externí odkaz:
https://doaj.org/article/9e622da572424f9dad2fb6932cf79adc
Autor:
Xujia Wu, Songhua Xiao, Maolei Zhang, Lixuan Yang, Jian Zhong, Bo Li, Fanying Li, Xin Xia, Xixi Li, Huangkai Zhou, Dawei Liu, Nunu Huang, Xuesong Yang, Feizhe Xiao, Nu Zhang
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-29 (2021)
Abstract Background Aberrant activation of the Hedgehog pathway drives tumorigenesis of many cancers, including glioblastoma. However, the sensitization mechanism of the G protein-coupled-like receptor smoothened (SMO), a key component of Hedgehog si
Externí odkaz:
https://doaj.org/article/a6142bd22c0a43eb91ae43fa9b57a8fb
Autor:
Xin Xia, Xixi Li, Fanying Li, Xujia Wu, Maolei Zhang, Huangkai Zhou, Nunu Huang, Xuesong Yang, Feizhe Xiao, Dawei Liu, Lixuan Yang, Nu Zhang
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background The RTK/PI3K/AKT pathway plays key roles in the development and progression of many cancers, including GBM. As a regulatory molecule and a potential drug target, the oncogenic role of AKT has been substantially studied. Three isof
Externí odkaz:
https://doaj.org/article/86eaa3e4497b4bc2b7efeb6bae81f7ce
Autor:
Xin Xia, Xixi Li, Fanying Li, Xujia Wu, Maolei Zhang, Huangkai Zhou, Nunu Huang, Xuesong Yang, Feizhe Xiao, Dawei Liu, Lixuan Yang, Nu Zhang
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-2 (2019)
In the published article [1], an error was noticed in Fig. 6B. The western blot results were reversed between the overexpression group and the knockdown group of circ-AKT3. The corrected and updated Fig. 6 is provided below. This error does not affec
Externí odkaz:
https://doaj.org/article/2f16349b54994f24aaa746f29df6d67b
Autor:
Huairui Yuan, Xujia Wu, Qiulian Wu, Adam Chatoff, Emily Megill, Jinjun Gao, Tengfei Huang, Tingting Duan, Kailin Yang, Chunyu Jin, Fanen Yuan, Shuai Wang, Linjie Zhao, Pascal O. Zinn, Kalil G. Abdullah, Yingming Zhao, Nathaniel W. Snyder, Jeremy N. Rich
Publikováno v:
Nature. 617:818-826
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c462d339ba47ae2d0ad06a57a7b49b10
https://doi.org/10.1038/s41586-023-06061-0
https://doi.org/10.1038/s41586-023-06061-0
Autor:
Jia Yang, Xujia Wu, Jia Wang, Xing Guo, Junju Chen, Xuesong Yang, Jian Zhong, Xixi Li, Zhong Deng
Publikováno v:
Cancer Science. 114:2053-2062
YAP/TAZ have been identified as master regulators in malignant phenotypes of glioblastoma (GBM), however, YAP/TAZ transcriptional disruptor in GBM treatment remains ineffective. Whether posttranscriptional disregulation of YAP/TAZ improving GBM outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0f1ff8ea28923d558bcc084c255b36
https://doi.org/10.1111/cas.15636
https://doi.org/10.1111/cas.15636
Publikováno v:
IEEE Wireless Communications. 29:38-43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7e78a94d2c246f004eddc470d9459f6
https://doi.org/10.1109/mwc.004.2100362
https://doi.org/10.1109/mwc.004.2100362