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Akademický článek

Coordinated Activation of VEGF/VEGFR-2 and PPARδ Pathways by a Multi-Component Chinese Medicine DHI Accelerated Recovery from Peripheral Arterial Disease in Type 2 Diabetic Mice.

Autor: Shuang He, Tiechan Zhao, Hao Guo, Yanzhi Meng, Gangjian Qin, David A Goukassian, Jihong Han, Xuimei Gao, Yan Zhu

Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0167305 (2016)

Diabetic mellitus (DM) patients are at an increased risk of developing peripheral arterial disease (PAD). Danhong injection (DHI) is a Chinese patent medicine widely used for several cardiovascular indications but the mechanism of action is not well-

Externí odkaz: https://doaj.org/article/17208ec10c6140baa8643b3a1300e272

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Selected Phytoestrogens Distinguish Roles of ERα Transactivation and Ligand Binding for Anti-Inflammatory Activity

Autor: Peng Zhang, Guanwei Fan, Zhongqun Zhang, Yan Zhu, Taiyi Wang, Barnabas Bessem Orang-Ojong, Shuang He, Xin Chai, Lanlan Pan, Hai-Xin Liu, Hong-Hua Wu, Xuimei Gao, Yun Seon Song, Richard H. Karas, Yuxin Feng, Qing Lu

Publikováno v: Endocrinology. 159(9)

Estrogen receptor α (ERα) is a ligand-activated transcriptional activator that is also involved vascular inflammation and atherosclerosis. Whether different ligands may affect this activity has not been explored. We screened a panel of phytoestroge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e6b96e7d56a86ab62b196b39ddbbde
https://pubmed.ncbi.nlm.nih.gov/30010822

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