Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Xuhu Mao"'
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Research impact is an important manifestation of research competence and the focus of medical education. This study is dedicated to exploring the relationships between coauthorship networks and the research impact of Chinese medical doctoral
Externí odkaz:
https://doaj.org/article/e08294db924245cdb1521a58f546789d
Autor:
Dongqi Nan, Chenglong Rao, Zhiheng Tang, Wenbo Yang, Pan Wu, Jiangao Chen, Yupei Xia, Jingmin Yan, Wenzheng Liu, Ziyuan Zhang, Zhiqiang Hu, Hai Chen, Yaling Liao, Xuhu Mao, Xiaoyun Liu, Quanming Zou, Qian Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mitophagy is critical for mitochondrial quality control and function to clear damaged mitochondria. Here, we found that Burkholderia pseudomallei maneuvered host mitophagy for its intracellular survival through the type III secretion system
Externí odkaz:
https://doaj.org/article/d0585fa8d04f416e8130477f0b37463e
Autor:
Chenglong Rao, Ziyuan Zhang, Jianpeng Qiao, Dongqi Nan, Pan Wu, Liting Wang, Changhao Yao, Senquan Zheng, Jinzhu Huang, Yaling Liao, Wenzheng Liu, Zhiqiang Hu, Shiwei Wang, Yuan Wen, Jingmin Yan, Xuhu Mao, Qian Li
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT Melioidosis is a serious infectious disease caused by the Gram-negative bacterium Burkholderia pseudomallei. Recently, Rab32-dependent immune vesicles emerge as a critical defense pathway to restrict the intracellular B. pseudomallei. Howeve
Externí odkaz:
https://doaj.org/article/f9b614b230a842048b9a6eaf66ec2d87
Autor:
Jie Tang, Xiaoxue Lu, Tao Zhang, Yuyang Feng, Qiaolin Xu, Jing Li, Yuanzhi Lan, Huaxing Luo, Linghai Zeng, Yuanyuan Xiang, Yan Zhang, Qian Li, Xuhu Mao, Bin Tang, Dongzhu Zeng
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e20012- (2023)
Shiga toxin type 2 (Stx2) is the primary virulence factor produced by Shiga toxin-producing enterohemorrhagic Escherichia coli (STEC), which causes epidemic outbreaks of gastrointestinal sickness and potentially fatal sequela hemolytic uremic syndrom
Externí odkaz:
https://doaj.org/article/0d51ba26e2834ad59725db60359aaacc
Autor:
Pan Wu, Chenglong Rao, Wenzheng Liu, Ziyuan Zhang, Dongqi Nan, Jiangao Chen, Minyang Wang, Yuan Wen, Jingmin Yan, Juanjuan Yue, Xuhu Mao, Qian Li
Publikováno v:
Pathogens, Vol 13, Iss 1, p 43 (2023)
Melioidosis, a severe tropical illness caused by Burkholderia pseudomallei, poses significant treatment challenges due to limited therapeutic options and the absence of effective vaccines. The pathogen’s intrinsic resistance to numerous antibiotics
Externí odkaz:
https://doaj.org/article/e1114159c9d74dd2b46472fc327e03f9
Autor:
Bin Tang, Xiaoxue Lu, Yanan Tong, Yuyang Feng, Yilan Mao, Guodong Dun, Jing Li, Qiaolin Xu, Jie Tang, Tao Zhang, Ling Deng, Xiaoyi He, Yuanzhi Lan, Huaxing Luo, Linghai Zeng, Yuanyuan Xiang, Qian Li, Dongzhu Zeng, Xuhu Mao
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106770- (2023)
Summary: Persistent Fusobacterium nucleatum infection is associated with the development of human colorectal cancer (CRC) and promotes tumorigenicity, but the underlying mechanisms remain unclear. Here, we reported that F. nucleatum promoted the tumo
Externí odkaz:
https://doaj.org/article/ae90b5f34be347eab65f1085866f3dd9
Autor:
Siqi Yuan, Yao Fang, Mengling Tang, Zhiqiang Hu, Chenglong Rao, Jiangao Chen, Yupei Xia, Meijuan Zhang, Jingmin Yan, Bin Tang, Xiaoyi He, Jianping Xie, Xuhu Mao, Qian Li
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Burkholderia pseudomallei, a facultative intracellular bacterium, is the aetiological agent of melioidosis that is responsible for up to 40% sepsis-related mortality in epidemic areas. However, no effective vaccine is available cu
Externí odkaz:
https://doaj.org/article/130f594b2b6e488ebd01a0dfb00d34c1
Autor:
Chenglong Rao, Chan Mao, Yupei Xia, Meijuan Zhang, Zhiqiang Hu, Siqi Yuan, Wenbo Yang, Jingmin Yan, Ling Deng, Xiaolian Cai, Xuhu Mao, Qian Li, Yaling Liao
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Burkholderia pseudomallei is a zoonotic pathogen that usually affects patients' lungs and causes serious melioidosis. The interaction of B. pseudomallei with its hosts is complex, and cellular response to B. pseudomallei infection in humans still rem
Externí odkaz:
https://doaj.org/article/200a6a63f375411eb8c73699f425a882
Autor:
Weilong Shang, Yifan Rao, Ying Zheng, Yi Yang, Qiwen Hu, Zhen Hu, Jizhen Yuan, Huagang Peng, Kun Xiong, Li Tan, Shu Li, Junmin Zhu, Ming Li, Xiaomei Hu, Xuhu Mao, Xiancai Rao
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) resists nearly all β-lactam antibiotics that have a bactericidal activity. However, whether the empirically used β-lactams enhance MRSA pathogenicity in vivo remains unclear. In this study
Externí odkaz:
https://doaj.org/article/eff6ce4468ec480f80be91e27f583649
Autor:
Jinyong Zhang, Xiaoli Zhang, Chao Wu, Dongshui Lu, Gang Guo, Xuhu Mao, Ying Zhang, Da-Cheng Wang, Defeng Li, Quanming Zou
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26205 (2011)
Arginase, a manganese-dependent enzyme that widely distributed in almost all creatures, is a urea cycle enzyme that catalyzes the hydrolysis of L-arginine to generate L-ornithine and urea. Compared with the well-studied arginases from animals and yea
Externí odkaz:
https://doaj.org/article/88298787f24a47b4a066dd49844e1c7b