Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xuhong Fu"'
Autor:
Xuhong Fu, Junjie Zhao, Guopeng Yu, Xiaomin Zhang, Jie Sun, Lingmeng Li, Jingyi Yin, Yinan Niu, Shancheng Ren, Yasheng Zhu, Bin Xu, Liyu Huang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
OTUD6A, a deubiquitinase, is amplified in prostate cancer and correlates with poor survivability, increasing the growth of prostate cancer cell lines and PDX models. OTUD6A stabilizes the expression of Brg1 and AR through the removal of K27- and K11-
Externí odkaz:
https://doaj.org/article/180201b6446946fc916cf5e39f534fac
Autor:
Li-Yu Huang, Junjie Zhao, Hao Chen, Lixin Wan, Hiroyuki Inuzuka, Jianping Guo, Xuhong Fu, Yangyang Zhai, Zhaoning Lu, Xuefei Wang, Ze-Guang Han, Yihong Sun, Wenyi Wei
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Upstream pathways regulating Brg1 stability and their role in carcinogenesis are unknown. Here they show Brg1 to be phosphorylated by CK1δ to promote its ubiquitination by SCFFBW7 (FBW7), Brg1 stabilization to promote gastric cancer metastasis, and
Externí odkaz:
https://doaj.org/article/84dbbd4c59c645519a4588dd6fbb6578
Autor:
Xuefei Wang, Liyu Huang, Yihong Sun, Jiarui Wu, Rong Zeng, Wenyi Wei, Jianping Guo, Peiyan Xia, Lingmeng Li, Chen Li, Junjie Zhao, Xuhong Fu, Haojie Li
Supplementary Figure from EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8f376530d28449376b6bdb655af036
https://doi.org/10.1158/1541-7786.22527882
https://doi.org/10.1158/1541-7786.22527882
Autor:
Meiyu Geng, Jian Ding, Xun Huang, Hong Liu, Minjia Tan, Min Huang, Mingyue Zheng, Aijun Shen, Linjiang Tong, Litong Nie, Jiang Wang, Yuan Xu, Danni Sun, Qiuming Pan, Xuhong Fu, Juan Yan, Xiaoyang Dai
Supplementary Table S2 shows the effect of aspirin on MDA-MB-231 lung metastasis in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f46aeca02906eedcff63afd936fad3
https://doi.org/10.1158/1078-0432.22462965.v1
https://doi.org/10.1158/1078-0432.22462965.v1
Autor:
Meiyu Geng, Jian Ding, Xun Huang, Hong Liu, Minjia Tan, Min Huang, Mingyue Zheng, Aijun Shen, Linjiang Tong, Litong Nie, Jiang Wang, Yuan Xu, Danni Sun, Qiuming Pan, Xuhong Fu, Juan Yan, Xiaoyang Dai
supplementary Figure S1 shows the annotated spectrum of VFQVVESTRPGK (326-337) from heparanase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3beec3c72155251d03d76cf31031bd
https://doi.org/10.1158/1078-0432.22462983.v1
https://doi.org/10.1158/1078-0432.22462983.v1
Autor:
Meiyu Geng, Jian Ding, Xun Huang, Hong Liu, Minjia Tan, Min Huang, Mingyue Zheng, Aijun Shen, Linjiang Tong, Litong Nie, Jiang Wang, Yuan Xu, Danni Sun, Qiuming Pan, Xuhong Fu, Juan Yan, Xiaoyang Dai
Purpose: Recent epidemiological and clinical studies have suggested the benefit of aspirin for patients with cancer, which inspired increasing efforts to demonstrate the anticancer ability of aspirin and reveal the molecular mechanisms behind. Nevert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f5878d7c3268f5803e630fbfdc9592
https://doi.org/10.1158/1078-0432.c.6525273
https://doi.org/10.1158/1078-0432.c.6525273
Autor:
Yakun Wang, Xuhong Fu, Yuge Zhao, Xuejia Kang, Yongzhuo Huang, Pengfei Zhao, Weimin Yin, Xiaopeng Mo
Publikováno v:
Theranostics. 10:6122-6135
EGFR TKI therapy has become a first-line regimen for non-small cell lung cancer (NSCLC) patients with EGRF mutations. However, there are two big challenges against effective therapy--the secondary EGFR mutation-associated TKI resistance and brain met
Autor:
Xuhong Fu, Junjie Zhao, Guopeng Yu, Xiaomin Zhang, Jie Sun, Lingmeng Li, Jingyi Yin, Yinan Niu, Shancheng Ren, Yasheng Zhu, Bin Xu, Liyu Huang
Publikováno v:
Communications biology. 5(1)
Ovarian tumor (OTU) subfamily deubiquitinases are involved in various cellular processes, such as inflammation, ferroptosis and tumorigenesis; however, their pathological roles in prostate cancer (PCa) remain largely unexplored. In this study, we obs
Autor:
Haojie Li, Xuhong Fu, Junjie Zhao, Chen Li, Lingmeng Li, Peiyan Xia, Jianping Guo, Wenyi Wei, Rong Zeng, Jiarui Wu, Yihong Sun, Liyu Huang, Xuefei Wang
Publikováno v:
Molecular cancer research : MCR. 20(7)
In comparison with intestinal-type gastric cancer, diffuse-type gastric cancer (DGC) is more likely to recur, metastasize, and exhibit worse clinical outcomes; however, the underlying mechanism of DGC recurrence remains elusive. By employing an LC/MS
Autor:
Qiongyu Shi, Cong Li, Zhanqing Cong, Yubo Zhou, Su Mingbo, Meiyu Geng, Jiang Wang, Xu Han, Fulin Lian, Xingling Zheng, Xingjun Li, Naixia Zhang, Xun Huang, Jia Li, Hong Liu, Hong Yang, Xuhong Fu, Shuni Wang, Rongrui Wei, Chunpu Li
Publikováno v:
European journal of medicinal chemistry. 222
Approximately 20% of multiple myeloma (MM) are caused by a chromosomal translocation t (4; 14) that leads to the overexpression of the nuclear receptor binding SET domain-protein 2 (NSD2) histone methyltransferase. NSD2 catalyzes the methylation of l