Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Xufeng Dai"'
Autor:
Hua Zhang, Xia Li, Xufeng Dai, Juanjuan Han, Yangyang Zhang, Yan Qi, Ying He, Yan Liu, Bo Chang, Ji-jing Pang
Publikováno v:
Journal of Ophthalmology, Vol 2017 (2017)
The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration
Externí odkaz:
https://doaj.org/article/e764f107064d4de7b49277b67109b46b
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188032 (2017)
Adeno-associated virus (AAV) vectors are important gene delivery tools for the treatment of many recessively inherited retinal diseases. For example, a wild-type (WT) AAV5 vector can deliver a full-length Cnga3 (cyclic nucleotide-gated channel alpha-
Externí odkaz:
https://doaj.org/article/c120dad1ed4444ccaa872be2cb16c8c3
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156542 (2016)
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is necessary for photoreceptors to generate an important lipid component of their membranes. The absence of LPCAT1 results in early and rapid rod and cone degeneration. Retinal degeneration 11 (rd11)
Externí odkaz:
https://doaj.org/article/3afe487003584693804b482a2a78ca79
Autor:
Yan Qi, Xufeng Dai, Hua Zhang, Ying He, Yangyang Zhang, Juanjuan Han, Ping Zhu, Yuxin Zhang, Qinxiang Zheng, Xia Li, Chen Zhao, Jijing Pang
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136523 (2015)
To introduce a practical method of subretinal injection in mice and evaluate injection-induced retinal detachment (RD) and damage using a dynamic imaging system, electrophysiology, and histology.After full dilation of a 2-month-old C57BL/6J mouse pup
Externí odkaz:
https://doaj.org/article/25e2c278396e4daf9431b9a9e7a369d2
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117570 (2015)
Early studies on Rpe65 knockout mice reported that remaining visual function was attributable to cone function. However, this finding has been challenged more and more as time has passed. Electroretinograms (ERGs) showed that rd12 mice, a spontaneous
Externí odkaz:
https://doaj.org/article/9b7d38f9b33741819411acdf48e46035
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Retinal degenerative diseases are one of the important refractory ophthalmic diseases, featured with apoptosis of photoreceptor cells. Histone acetylation and deacetylation can regulate chromosome assembly, gene transcription, and posttranslational m
Externí odkaz:
https://doaj.org/article/49069e6f356c4f2fa91443239a23648d
Autor:
Ji-jing Pang, Wen-Tao Deng, Xufeng Dai, Bo Lei, Drew Everhart, Yumiko Umino, Jie Li, Keqing Zhang, Song Mao, Sanford L. Boye, Li Liu, Vince A. Chiodo, Xuan Liu, Wei Shi, Ye Tao, Bo Chang, William W. Hauswirth
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/dc2dd842f0f744fbb9fe98631e870674
Autor:
Ji-jing Pang, Wen-Tao Deng, Xufeng Dai, Bo Lei, Drew Everhart, Yumiko Umino, Jie Li, Keqing Zhang, Song Mao, Sanford L Boye, Li Liu, Vince A Chiodo, Xuan Liu, Wei Shi, Ye Tao, Bo Chang, William W Hauswirth
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35250 (2012)
Achromatopsia is a rare autosomal recessive disorder which shows color blindness, severely impaired visual acuity, and extreme sensitivity to bright light. Mutations in the alpha subunits of the cone cyclic nucleotide-gated channels (CNGA3) are respo
Externí odkaz:
https://doaj.org/article/652baf12f6c64bd4844fc98e057c2f3a
Autor:
Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Yuanping Zhang, Bo Chen, Jiangping Hou, Chunhui Zhao, Jiali Zhu, Ying Zhang, Xufeng Dai, Shan Ma, Jia Li, Jijing Pang, Jia Qu, Wensheng Li
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44855 (2012)
Leber congenital amaurosis (LCA) is one of the most severe forms of inherited retinal degeneration and can be caused by mutations in at least 15 different genes. To clarify the proteomic differences in LCA eyes, a cohort of retinal degeneration 12 (r
Externí odkaz:
https://doaj.org/article/46865d8a1dc1435f921b3939c729579a
Publikováno v:
Experimental Eye Research. 179:106-114
The Cacna1f gene encodes the α1F subunit of an L-type voltage-gated calcium channel, Cav1.4. In photoreceptor synaptic terminals, Cav1.4 channels mediate glutamate release and postsynaptic responses associated with visual signal transmission. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e20f60be2abc0f1bbad41d061612751
https://doi.org/10.1016/j.exer.2018.11.010
https://doi.org/10.1016/j.exer.2018.11.010