Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xuezhou Hou"'
Autor:
Hee Sun Choi, Taejoon Won, Xuezhou Hou, Guobao Chen, William Bracamonte-Baran, Monica V. Talor, Ivana Jurčová, Ondrej Szárszoi, Lenka Čurnova, Ilja Stříž, Jody E. Hooper, Vojtěch Melenovský, Daniela Čiháková
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 2989-3003.e6 (2020)
Summary: We find that cardiac group 2 innate lymphoid cells (ILC2s) are essential for the development of IL-33-induced eosinophilic pericarditis. We show a pathogenic role for ILC2s in cardiac inflammation, in which ILC2s activated by IL-33 drive the
Externí odkaz:
https://doaj.org/article/4d2bebf86a2c4552b5964ddd17e36bc0
Autor:
Xuezhou Hou, Guobao Chen, William Bracamonte-Baran, Hee Sun Choi, Nicola L. Diny, Jungeun Sung, David Hughes, Taejoon Won, Megan Kay Wood, Monica V. Talor, David Joel Hackam, Karin Klingel, Giovanni Davogustto, Heinrich Taegtmeyer, Isabelle Coppens, Jobert G. Barin, Daniela Čiháková
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 172-189.e7 (2019)
Summary: Two types of monocytes, Ly6Chi and Ly6Clo, infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a role for cardiac fibroblasts in facilitating monocyte-to-macrophage differentiation of both Ly6Chi and Ly6Cl
Externí odkaz:
https://doaj.org/article/b6b5be67eb354a43a097237f7256ed86
Autor:
William Bracamonte-Baran, Guobao Chen, Xuezhou Hou, Monica V. Talor, Hee Sun Choi, Giovanni Davogustto, Heinrich Taegtmeyer, Jungeun Sung, David Joel Hackam, David Nauen, Daniela Čiháková
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Innate lymphoid cells (ILC) are a subset of leukocytes with lymphoid properties that lack antigen specific receptors. They can be stimulated by and exert their effect via specific cytokine axes, whereas Natural Killers (NK) cells are the only known c
Externí odkaz:
https://doaj.org/article/045793709dc24b8e88455b62d435752f
Autor:
Roberta B. Ness, Patricia A. Totten, Xuezhou Hou, Tina L. Fiedler, Daisy Ko, Fouzia Farooq, David N. Fredricks, Gong Tang, Sujatha Srinivasan, Sabina G. Astete, Catherine L. Haggerty
Publikováno v:
Sex Transm Dis
In a vaginal 16S ribosomal RNA gene quantitative PCR study of 17 pelvic inflammatory disease (PID) cases and 17 controls who tested positive for Chlamydia trachomatis, women who additionally tested positive for Atopobium vaginae, Sneathia spp., BVAB-
Autor:
Hongpeng Jia, Jungeun Sung, Xuezhou Hou, Daniela Cihakova, Qinjie Zhou, Lysandra Voltaggio, David J. Hackam, Chhinder P. Sodhi
Publikováno v:
Mucosal immunology
Mucosal healing occurs through migration and proliferation of cells within injured epithelium, yet these processes may be inadequate for mucosal healing after significant injury where the mucosa is denuded. We hypothesize that extra-intestinal cells
Autor:
Ari Waisman, Xuezhou Hou, Heinrich Taegtmeyer, Kai Fu, Nicola L. Diny, Yue Liu, William Bracamonte-Baran, Daniela Cihakova, Hernan G. Vasquez, Fengyi Wan, Simon J. Conway, Giovanni Davogustto, Guobao Chen, Monica V. Talor, O. Howard Frazier
Publikováno v:
European Journal of Immunology. 48:1522-1538
The causative effect of GM-CSF produced by cardiac fibroblasts to development of heart failure has not been shown. We identified the pathological GM-CSF-producing cardiac fibroblast subset and the specific deletion of IL-17A signaling to these cells
Autor:
Djahida Bedja, Monica V. Talor, Guobao Chen, Daniel A. Peterson, Ashley B. Cardamone, Elizabeth Gebremariam, Daniela Cihakova, Julie Schaub, Lei Wu, Hee Sun Choi, Xuezhou Hou, SuFey Ong, Jobert G. Barin, Nicola L. Diny, Noel R. Rose
Publikováno v:
Experimental and Molecular Pathology. 103:141-152
The extensive, diverse communities that constitute the microbiome are increasingly appreciated as important regulators of human health and disease through inflammatory, immune, and metabolic pathways. We sought to elucidate pathways by which microbio
Autor:
Guobao Chen, Noel R. Rose, Xuezhou Hou, Julie Schaub, Karin Klingel, Jobert G. Barin, Daniela Cihakova, Monica V. Talor, Stuart D. Russell, Nicola L. Diny
Publikováno v:
European Journal of Immunology. 46:2749-2760
Cardiac manifestations are a major cause of morbidity and mortality in patients with eosinophil-associated diseases. Eosinophils are thought to play a pathogenic role in myocarditis. We investigated the pathways that recruit eosinophils to the heart
Autor:
Xuezhou Hou, Daniela Cihakova, Nathan K. Archer, Matthew Hoyer, Lloyd S. Miller, Noel R. Rose, Julie Schaub, Elizabeth Gebremariam, Meghan F. Davis, Monica V. Talor, Jobert G. Barin, Nicola L. Diny
Publikováno v:
The American Journal of Pathology. 186:2337-2352
Infections with Staphylococcus aureus are a continuing and growing problem in community and hospital settings. Preclinical animal modeling of S. aureus relies on experimental infection, which carries some limitations. We describe here a novel, sponta
Autor:
Monica V. Talor, Xuezhou Hou, Nicola L. Diny, Lei Wu, SuFey Ong, Noel R. Rose, Daniela Cihakova, Jobert G. Barin
Publikováno v:
European Journal of Immunology. 46:582-592
Using a mouse model of experimental autoimmune myocarditis (EAM), we showed for the first time that IL-23 stimulation of CD4(+) T cells is required only briefly at the initiation of GM-CFS-dependent cardiac autoimmunity. IL-23 signal, acting as a swi