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Akademický článek

Cortical lipid metabolic pathway alteration of early Alzheimer’s disease and candidate drugs screen

Autor: Linshuang Wang, Fengxue Qu, Xueyun Yu, Sixia Yang, Binbin Zhao, Yaojing Chen, Pengbo Li, Zhanjun Zhang, Junying Zhang, Xuejie Han, Dongfeng Wei

Publikováno v: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-23 (2024)

Abstract Background Lipid metabolism changes occur in early Alzheimer's disease (AD) patients. Yet little is known about metabolic gene changes in early AD cortex. Methods The lipid metabolic genes selected from two datasets (GSE39420 and GSE118553)

Externí odkaz: https://doaj.org/article/73a6268f70ca4853ae1025585bb73bdc

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The Fitting Optimization Path Analysis on Scale Missing Data: Based on the 507 Patients of Poststroke Depression Measured by SDS

Autor: Xiaoying Lv, Ruonan Zhao, Tongsheng Su, Liyun He, Rui Song, Qizhen Wang, Xueyun Yu, Yanbo Zhu

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2022 (2022)

Objective. To explore the optimal fitting path of missing data of the Scale to make the fitting data close to the real situation of patients’ data. Methods. Based on the complete data set of the SDS of 507 patients with stroke, the data simulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64531d76c606199d05bf33d7ce3d2371
https://pubmed.ncbi.nlm.nih.gov/35069761

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PPARγ and mitophagy are involved in hypoxia/reoxygenation-induced renal tubular epithelial cells injury

Autor: Zhiyang Xi, Ling Jiang, Luming Wei, Yuan-Han Qin, Xueyun Yu

Publikováno v: Journal of Receptors and Signal Transduction. 39:235-242

Renal tubular epithelial cell (RTEC) injury is the main cause and common pathological process of various renal diseases. Mitochondrial dysfunction (MtD) is a pathological process after renal injury. Mitophagy is vital for mitochondrial function. Hypo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f882c1fb53b0e8fc146149d6345f81
https://doi.org/10.1080/10799893.2019.1660894

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Protective effect of retinoic acid receptor α on hypoxia-induced epithelial to mesenchymal transition of renal tubular epithelial cells associated with TGF-β/MMP-9 pathway

Autor: Ling Jiang, Xueyun Yu, Yuanhan Qin, Xingbo Jiang, Ling Gong, Kunling Song

Publikováno v: Cell Biology International. 42:1050-1059

Retinoic acid receptor α (RARα), a member of family of the nuclear retinoic acid receptors (RARs), plays an essential role in various chronic kidney diseases (CKD). Renal tubular epithelial to mesenchymal transition (EMT) is a common mechanism of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::936a7691c99cbf432823d1389299e4bb
https://doi.org/10.1002/cbin.10982

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Protective effect of retinoic acid receptor α on hypoxia-induced epithelial to mesenchymal transition of renal tubular epithelial cells associated with TGF-β/MMP-9 pathway

Autor: Ling, Gong, Ling, Jiang, Yuanhan, Qin, Xingbo, Jiang, Kunling, Song, Xueyun, Yu

Publikováno v: Cell biology international. 42(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e99ccc373dfa9ac224f4912d7abcba0
https://pubmed.ncbi.nlm.nih.gov/29719094

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A novel classification method for aid decision of traditional Chinese patent medicines for stroke treatment

Autor: Bo Liu, Yuxue Zhao, Xueyun Yu, Yufeng Zhao, Lin Luo, Baoyan Liu, Bai Wenjing, Liyun He, Peijing Rong, Guo-Zheng Li, Xinyu Cao

Publikováno v: Frontiers of medicine. 11(3)

Traditional Chinese patent medicines are widely used to treat stroke because it has good efficacy in the clinical environment. However, because of the lack of knowledge on traditional Chinese patent medicines, many Western physicians, who are account

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d644d1e80150cca791eee06797df7ef3
https://pubmed.ncbi.nlm.nih.gov/28500428

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