Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xueyu Hao"'
Publikováno v:
MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)
Abstract Noninvasive pharmacological strategies like nicotinamide mononucleotide (NMN) supplementation can effectively address age‐related ovarian infertility by maintaining or enhancing oocyte quality and quantity. This study revealed that ovarian
Externí odkaz:
https://doaj.org/article/959cc543d5714dba8dd0c6ade3feb646
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139578 (2015)
In this study, HPRP-A2, a synthetic 15-mer cationic peptides with all D-amino acids, effectively inhibited the survival of gastric cell lines in a dose-dependent manner. Gastric tumor cells killing by HPRP-A2 involves a rapid collapse of the membrane
Externí odkaz:
https://doaj.org/article/d74d7efc97174dcca6d3c248640d0e9a
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138911 (2015)
HPRP-A1 is an amphipathic α-helical anticancer peptide (ACP) derived from the N-terminus of ribosomal protein L1 (RpL1) of Helicobacter pylori. In our previously study, HPRP-A1 has been reported that induced HeLa cell apoptosis in a caspase-dependen
Externí odkaz:
https://doaj.org/article/56836fc4e8b342b290335fbdf96d27a8
Autor:
Xueyu Hao, Chunjie Li, Hongyu Zhao, Wanli Wei, Chengbin Li, Rizhe Jin, Chuanqing Kang, Lianxun Gao
Publikováno v:
Chemico-biological interactions. 370
Targeting and stabilizing nonclassical DNA G-quadruplexes (G4s) with a ligand to inhibit cell proliferation is a very promising approach for cancer treatment. Here, we demonstrate that the combination of a naphthalenediimide (NDI) ligand and a squara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5b756a8abee9a82b00c4b1f10d228e
https://pubmed.ncbi.nlm.nih.gov/36563735
https://pubmed.ncbi.nlm.nih.gov/36563735
Publikováno v:
Chemical Research in Chinese Universities. 37:795-800
G-Quadruplexes(GQs), which are formed by G-rich DNA sequences in human telomeres, have become an attractive target for cancer treatment. The ligands to stabilize the conformation of human telomeric GQs in vivo are particularly important for structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c20da9669baabc8e822b39e4602727e8
https://doi.org/10.1007/s40242-021-1022-9
https://doi.org/10.1007/s40242-021-1022-9
Autor:
Chunjie Li, Yu Wang, Xueyu Hao, Jingwei Hou, Feng Zhang, Rizhe Jin, Chuanqing Kang, Lianxun Gao
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af98241c8f9e27d9b23d30197bf3dd76
https://doi.org/10.2139/ssrn.4182402
https://doi.org/10.2139/ssrn.4182402
Autor:
Ding Peng, Weimin Ci, Liqun Zhou, Xueyu Hao, Bao Guan, Xuesong Li, Zhengzheng Xu, XiKang Wu, Guangzhe Ge, Jilu Wang, Bao Zhang, Huiying He, Yuanyuan Zhou, Zhentao Lei, Huan Lu, Yue Shi
Publikováno v:
European Urology. 77:288-290
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401f6e6367bfae027c744ac79a64d309
https://doi.org/10.1016/j.eururo.2019.11.006
https://doi.org/10.1016/j.eururo.2019.11.006
Autor:
Qi Shen, Guangzhe Ge, Qun He, Xiaoyun Zhang, Weimin Ci, Liqun Zhou, Jie Qi, Guangpu Ding, Zhengzheng Xu, Yanqing Gong, Yifan Li, Xuesong Li, Bao Guan, Yuanyuan Zhou, Ding Peng, Yue Shi, Xueyu Hao, Yonghao Zhan, Huan Lu, Yucai Wu
Publikováno v:
Clinical Chemistry. 66:188-198
BACKGROUND Current noninvasive assays for urothelial carcinoma (UC) lack clinical sensitivity and specificity. Given the utility of plasma cell-free DNA (cfDNA) biomarkers, the development of urinary cfDNA biomarkers may improve the diagnostic sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2af17c76d1341bf11f8cc0e06fb5ee6
https://doi.org/10.1373/clinchem.2019.309633
https://doi.org/10.1373/clinchem.2019.309633
Autor:
Xueyu Hao, Lianxun Gao, Rizhe Jin, Xiaoye Ma, Chuanqing Kang, Liangpeng Wang, Chunjie Li, Yu Wang
Publikováno v:
Bioorganicmedicinal chemistry. 48
The development of ligands to stabilize G-quadruplexes (G4s) or induce G4s to transition from metastable topology to stable topology is a potential strategy for inhibiting cancer cell proliferation. In this study, a novel G-quadruplex (G4) ligand bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2849605b3488b7bc2c1a2bb1ad2e0557
https://pubmed.ncbi.nlm.nih.gov/34560615
https://pubmed.ncbi.nlm.nih.gov/34560615
Autor:
Xueyu Hao, Chunjie Li, Rizhe Jin, Lianxun Gao, Yu Wang, Chuanqing Kang, Xiaoye Ma, Liangpeng Wang
Publikováno v:
Organicbiomolecular chemistry. 19(21)
G-quadruplex (GQ) ligands as potential anti-cancer drugs have received extensive attention. Large aromatic systems are usually considered in the design of the ligands to improve the binding with GQs, which are typically constructed by the combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5cdd3e7304814c1e6f3bb041b7c46d7
https://pubmed.ncbi.nlm.nih.gov/33978052
https://pubmed.ncbi.nlm.nih.gov/33978052