Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Xueying C. Li"'
Autor:
Xueying C. Li, Lautaro Gandara, Måns Ekelöf, Kerstin Richter, Theodore Alexandrov, Justin Crocker
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Although the effects of genetic and environmental perturbations on multicellular organisms are rarely restricted to single phenotypic layers, our current understanding of how developmental programs react to these challenges remains limited.
Externí odkaz:
https://doaj.org/article/53f1b425f7334328a6df8dc691dc232c
Autor:
Xueying C. Li, Justin C. Fay
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3595-3600 (2019)
Under the model of micromutationism, phenotypic divergence between species is caused by accumulation of many small-effect changes. While mapping the causal changes to single nucleotide resolution could be difficult for diverged species, genetic disse
Externí odkaz:
https://doaj.org/article/33d8cf972073483a8cb720ca3c9100f8
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 378
Rapid enhancer and slow promoter evolution have been demonstrated through comparative genomics. However, it is not clear how this information is encoded genetically and if this can be used to place evolution in a predictive context. Part of the chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3acdbcfef87f9dec6e8747f1b0eec3
https://doi.org/10.1098/rstb.2022.0054
https://doi.org/10.1098/rstb.2022.0054
Rapid enhancer and slow promoter evolution have been demonstrated through comparative genomics. However, it is not clear how this information is encoded genetically and if this can be used to place evolution in a predictive context. Part of the chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c29b81c8208eb558b0f73ca9664b027e
https://doi.org/10.1101/2022.10.17.512533
https://doi.org/10.1101/2022.10.17.512533
Autor:
Xueying C. Li, Lautaro Gandara, Mans Ekelof, Kerstin Richter, Theodore Alexandrov, Justin Crocker
It remains unknown how developmental systems evolve in response to variable genetic and environmental conditions. Here, we have examined the evolvability of the classic bicoid network in Drosophila, which is essential for anterior-posterior patternin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103c3df4a28b97f6e9bb41c3a7977640
https://doi.org/10.1101/2022.09.28.509860
https://doi.org/10.1101/2022.09.28.509860
Autor:
Justin C. Fay, Xueying C. Li
Publikováno v:
Genome Biology and Evolution
Gene regulation is a ubiquitous mechanism by which organisms respond to their environment. While organisms are often found to be adapted to the environments they experience, the role of gene regulation in environmental adaptation is not often known.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa407f744e8c1a00a35106ae8e66358
https://doi.org/10.1093/gbe/evx072
https://doi.org/10.1093/gbe/evx072
Autor:
Yong Tao, Qin Ma, Jun Cai, Di Wang, Xueying C. Li, Hurng-Yi Wang, Yingrui Li, Xuemei Lu, Yadong Zhang, Tao Li, Tianqi Zhu, Jialin Liu, Jue Ruan, Zheng Hu, Xu Shen
Publikováno v:
Molecular biology and evolution. 36(3)
Large genomes with elevated mutation rates are prone to accumulating deleterious mutations more rapidly than natural selection can purge (Muller's ratchet). As a consequence, it may lead to the extinction of small populations. Relative to most unicel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48669a050c33c1beb4338bb56c2165d7
https://pubmed.ncbi.nlm.nih.gov/30802908
https://pubmed.ncbi.nlm.nih.gov/30802908
Autor:
Ryan V. Moriarty, Justin C. Fay, Xueying C. Li, David Peris, EmilyClare P. Baker, Chris Todd Hittinger
Publikováno v:
Science Advances
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
instname
A growing body of research suggests that the mitochondrial genome (mtDNA) is important for temperature adaptation. In the yeast genus Saccharomyces, species have diverged in temperature tolerance, driving their use in high- or low-temperature ferment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f068177c0fc07d3e7d92f15404ee50e
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Science Advances
instname
Science Advances
Genetic analysis of phenotypic differences between species is typically limited to interfertile species. Here, we conducted a genome-wide noncomplementation screen to identify genes that contribute to a major difference in thermal growth profile betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf02e60f200cc328f338bfd4f7c75d4f
http://hdl.handle.net/10261/194927
http://hdl.handle.net/10261/194927
Autor:
Qin Ma, Yong Tao, Tianqi Zhu, Jue Ruan, Hurng-Yi Wang, Yingrui Li, Jialin Liu, Xu Shen, Jun Cai, Caihong Zheng, Zheng Hu, Chung-I Wu, Xueying C. Li, Yadong Zhang, Di Wang, Tao Li, Xuemei Lu
ABSRACTLarge and non-recombining genomes are prone to accumulating deleterious mutations faster than natural selection can purge (Muller’s ratchet). A possible consequence would then be the extinction of small populations. Relative to most single-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d83391b7d0753a06a6e86caf4877401