Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Xueya Zhou"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract Background Deletion of haploinsufficient genes or duplication of triplosensitive ones results in phenotypic effects in a concentration-dependent manner, and the mechanisms underlying these dosage-sensitive effects remain elusive. Phase separ
Externí odkaz:
https://doaj.org/article/4a722bf1a45b47b4a29981d2ac925c9f
Autor:
Na Zhu, Emilia M. Swietlik, Carrie L. Welch, Michael W. Pauciulo, Jacob J. Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A. Lutz, Jennifer M. Martin, Carmen M. Treacy, Erika B. Rosenzweig, Usha Krishnan, Anna W. Coleman, Claudia Gonzaga-Juaregui, Allan Lawrie, Richard C. Trembath, Martin R. Wilkins, Regeneron Genetics Center, PAH Biobank Enrolling Centers’ Investigators, NIHR BioResource for Translational Research - Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, Nicholas W. Morrell, Yufeng Shen, Stefan Gräf, William C. Nichols, Wendy K. Chung
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Pulmonary arterial hypertension (PAH) is a lethal vasculopathy characterized by pathogenic remodeling of pulmonary arterioles leading to increased pulmonary pressures, right ventricular hypertrophy, and heart failure. PAH can be a
Externí odkaz:
https://doaj.org/article/7d26217cb5954a278edcedd89f0346c6
Publikováno v:
Soil and Water Research, Vol 14, Iss 4, Pp 229-239 (2019)
Soil water dynamic is considered an important process for water resource and plantation management in Horqin Sand Land, northern China. In this study, soil water content simulated by the SWMS-2D model was used to systematically analyse soil water dyn
Externí odkaz:
https://doaj.org/article/ebf8f25fabda41db8cdfb85bd8ef97d1
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
This study expands on the impact of local government environmental regulation on enterprise environmental protection investment. Furthermore, it analyzes the influence promotion pressure of officials has on the scale of enterprise environmental inves
Externí odkaz:
https://doaj.org/article/19c5523585694cc79d72e579564f054d
Autor:
Na Zhu, Emilia M. Swietlik, Carrie L. Welch, Michael W. Pauciulo, Jacob J. Hagen, Xueya Zhou, Yicheng Guo, Johannes Karten, Divya Pandya, Tobias Tilly, Katie A. Lutz, Jennifer M. Martin, Carmen M. Treacy, Erika B. Rosenzweig, Usha Krishnan, Anna W. Coleman, Claudia Gonzaga-Jauregui, Allan Lawrie, Richard C. Trembath, Martin R. Wilkins, Regeneron Genetics Center, PAH Biobank Enrolling Centers’ Investigators, NIHR BioResource for Translational Research - Rare Diseases, National Cohort Study of Idiopathic and Heritable PAH, Nicholas W. Morrell, Yufeng Shen, Stefan Gräf, William C. Nichols, Wendy K. Chung
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/2f9c2543b76a476ea740d73fa0a70388
Autor:
Hongjian Qi, Lan Yu, Xueya Zhou, Julia Wynn, Haoquan Zhao, Yicheng Guo, Na Zhu, Alexander Kitaygorodsky, Rebecca Hernan, Gudrun Aspelund, Foong-Yen Lim, Timothy Crombleholme, Robert Cusick, Kenneth Azarow, Melissa E Danko, Dai Chung, Brad W Warner, George B Mychaliska, Douglas Potoka, Amy J Wagner, Mahmoud ElFiky, Jay M Wilson, Debbie Nickerson, Michael Bamshad, Frances A High, Mauro Longoni, Patricia K Donahoe, Wendy K Chung, Yufeng Shen
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007822 (2018)
Congenital diaphragmatic hernia (CDH) is a severe birth defect that is often accompanied by other congenital anomalies. Previous exome sequencing studies for CDH have supported a role of de novo damaging variants but did not identify any recurrently
Externí odkaz:
https://doaj.org/article/5ee7f177ac4c4fcaa1154d035c69c6ac
Autor:
Xueya Zhou, Ching-Lung Cheung, Tatsuki Karasugi, Jaro Karppinen, Dino Samartzis, Yi-Hsiang Hsu, Timothy Shin-Heng Mak, You-Qiang Song, Kazuhiro Chiba, Yoshiharu Kawaguchi, Yan Li, Danny Chan, Kenneth Man-Chee Cheung, Shiro Ikegawa, Kathryn Song-Eng Cheah, Pak Chung Sham
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Lumbar disc degeneration (LDD) is age-related break-down in the fibrocartilaginous joints between lumbar vertebrae. It is a major cause of low back pain and is conventionally assessed by magnetic resonance imaging (MRI). Like most other complex trait
Externí odkaz:
https://doaj.org/article/41dee9ff860e41408090c216c879775d
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 5, p e1005502 (2017)
Post-translational modifications (PTMs) add a further layer of complexity to the proteome and regulate a wide range of cellular protein functions. With the increasing number of known PTM sites, it becomes imperative to understand their functional int
Externí odkaz:
https://doaj.org/article/42d9c69b76f24eceb81f40b7cf217b53
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Soil and Water Research. 14:229-239