Zobrazeno 1 - 10
of 747
pro vyhledávání: '"Xuetao Cao"'
Autor:
Jiaming Wang, Xuetao Cao
Publikováno v:
Cancer Communications, Vol 44, Iss 5, Pp 580-583 (2024)
Externí odkaz:
https://doaj.org/article/3fa979fbe7124d69a8481d02c8c62203
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114608- (2024)
Summary: Ubiquitination is essential for the proteasomal turnover of IRF3, the central factor mediating the antiviral innate immune response. However, the spatiotemporal regulation of IRF3 ubiquitination for the precise activation and timely resoluti
Externí odkaz:
https://doaj.org/article/d7699948531a4d729f0c45b761a106de
Autor:
Jiacheng Wu, Xiaoqing Xu, Jiaqi Duan, Yangyang Chai, Jiaying Song, Dongsheng Gong, Bingjing Wang, Ye Hu, Taotao Han, Yuanyuan Ding, Yin Liu, Jingnan Li, Xuetao Cao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract TNF acts as one pathogenic driver for inducing intestinal epithelial cell (IEC) death and substantial intestinal inflammation. How the IEC death is regulated to physiologically prevent intestinal inflammation needs further investigation. Her
Externí odkaz:
https://doaj.org/article/36fa4a6134b44c92b1e5dcf70c12c3c0
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Memory CD8+ T cell generation is crucial for pathogen elimination and effective vaccination against infection. The cellular and molecular circuitry that underlies the generation of memory CD8+ T cells remains elusive. Eosinophils can modulat
Externí odkaz:
https://doaj.org/article/2fab8e69e1b742ca916f2c727bd53b30
Autor:
Yan Jiang, Siqi Sun, Yuan Quan, Xin Wang, Yuling You, Xiao Zhang, Yue Zhang, Yin Liu, Bingjing Wang, Henan Xu, Xuetao Cao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Innate sensors initiate the production of type I interferons (IFN-I) and proinflammatory cytokines to protect host from viral infection. Several innate nuclear sensors that mainly induce IFN-I production have been identified. Whether there e
Externí odkaz:
https://doaj.org/article/fa7cfe52cd9b45a8aa25fac08a37f539
Autor:
Xue Gao, Shiying Niu, Lulu Li, Xiaoyue Zhang, Xuetao Cao, Xinhui Zhang, Wentao Pan, Meili Sun, Guoli Zhao, Xuezhen Zheng, Guohua Song, Yueying Zhang
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30902- (2024)
Background: Radiotherapy has become a standard treatment for chest tumors, but a common complication of radiotherapy is radiation lung injury. Currently, there is still a lack of effective treatment for radiation lung injury. Methods: A mouse model o
Externí odkaz:
https://doaj.org/article/9699d881ebca4c40ab88c0a80e038c7b
Autor:
Yan Jiang, Siqi Sun, Yuan Quan, Xin Wang, Yuling You, Xiao Zhang, Yue Zhang, Yin Liu, Bingjing Wang, Henan Xu, Xuetao Cao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/59397184c11f49359725a84ba3664f4a
Autor:
Liyuan Zhang, Yue Dong, Luxin Zhang, Minjun Wang, Ye Zhou, Kaiwei Jia, Suyuan Wang, Mu Wang, Yunhui Li, Shudan Luo, Shan Lu, Yiwen Fan, Dingji Zhang, Yingyun Yang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-11 (2023)
Abstract Hepatocarcinogenesis is initiated by repeated hepatocyte death and liver damage, and the underlying mechanisms mediating cell death and the subsequent carcinogenesis remain to be fully investigated. Immunoresponsive gene 1 (IRG1) and its enz
Externí odkaz:
https://doaj.org/article/8b0643ea588b4493b347879a6c25e75c
Autor:
Jiacheng Wu, Ye Hu, Jiaying Song, Jia Xu, Qian Zhang, Yangyang Chai, Xin Wang, Bingjing Wang, Yong Zhao, Xuetao Cao, Xiaoqing Xu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-13 (2023)
Abstracts Phosphorylation of IRF3 is critical to induce type I interferon (IFN-I) production in antiviral innate response. Here we report that lysine methyltransferase SMYD2 inhibits the expressions of IFN-I and proinflammatory cytokines in macrophag
Externí odkaz:
https://doaj.org/article/cb1d392f948c4252962e2bca388a3ec4
Autor:
Jiaying Huang, Zhou Yu, Xuelian Li, Mingjin Yang, Qian Fang, Zheng Li, Chunmei Wang, Taoyong Chen, Xuetao Cao
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-12 (2023)
Abstract Uncontrolled viral replication and excessive inflammation are the main causes of death in the host infected with virus. Hence inhibition of intracellular viral replication and production of innate cytokines, which are the key strategies of h
Externí odkaz:
https://doaj.org/article/d10ebe2e13e643cc9ae8835c3d5c63ca