Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Xuetao Pei"'
Autor:
Hao Yan, Ruge Zang, Tiantian Cui, Yiming Liu, Biao Zhang, Lingpin Zhao, Hongyu Li, Juannian Zhou, Haiyang Wang, Quan Zeng, Lei Xu, Yuqi Zhou, Xuetao Pei, Jiafei Xi, Wen Yue
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), can undergo erythroid differentiation, offering a potentially invaluable resource for generating large
Externí odkaz:
https://doaj.org/article/8d847198eb7849ca8a7b9af25734b196
Autor:
Xin Yuan, Pengcong Liu, Lei Xu, Liqing Liang, Qian Dong, Tao Fan, Wen Yue, Mingyi Qu, Xuetao Pei, Xiaoyan Xie
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Proper control of the lineage bias of megakaryocytic and erythroid progenitor cells (MEPs) is of significant importance, the disorder of which will lead to abnormalities in the number and function of platelets and erythrocytes. Un
Externí odkaz:
https://doaj.org/article/ebe30320e04c4b4f8d56f918d1b1637d
Autor:
Keyi Chen, Yunqiao Li, Xumin Wu, Xuan Tang, Bowen Zhang, Tao Fan, Lijuan He, Xuetao Pei, Yanhua Li
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Human hematopoietic organoids have a wide application value for modeling human bone marrow diseases, such as acute hematopoietic radiation injury. However, the manufacturing of human hematopoietic organoids is an unaddressed chall
Externí odkaz:
https://doaj.org/article/a1e645bb87aa4f338b9d5171c47ddf03
Autor:
Xiaoling Wang, Tiantian Cui, Hao Yan, Lingping Zhao, Ruge Zang, Hongyu Li, Haiyang Wang, Biao Zhang, Junnian Zhou, Yiming Liu, Wen Yue, Jiafei Xi, Xuetao Pei
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37463- (2024)
Tribbles pseudokinase 3 (TRIB3) expression significantly increases during terminal erythropoiesis in vivo. However, we found that TRIB3 expression remained relatively low during human embryonic stem cell (hESC) erythropoiesis, particularly in the lat
Externí odkaz:
https://doaj.org/article/397191ba5f7b480cad7e58d8d3b619bb
Autor:
Chao Wang, Bichun Zhao, Jinglei Zhai, Ailin Wang, Ning Cao, Tuling Liao, Ruyu Su, Lijuan He, Yanhua Li, Xuetao Pei, Yali Jia, Wen Yue
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-11 (2023)
Abstract With the expansion of the aging population, age-associated sarcopenia (AAS) has become a severe clinical disease of the elderly and a key challenge for healthy aging. Regrettably, no approved therapies currently exist for treating AAS. In th
Externí odkaz:
https://doaj.org/article/15e7b75a32184ce4acb37b6545117bea
Autor:
Fang Fang, Lei Xu, Liqing Liang, Mingyi Qu, Hailei Yao, Wen Yue, Lin Chen, Dongli Chen, Zeng Fan, Lijuan He, Xue Nan, Huanhuan Zhang, Xiaoyan Xie, Xuetao Pei
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-15 (2022)
Abstract Erythroblast enucleation is a precisely regulated but not clearly understood process. Polycythemia shows pathological erythroblast enucleation, and we discovered a low miR-125b-5p level in terminal erythroblasts of patients with polycythemia
Externí odkaz:
https://doaj.org/article/b051dde5d7fc4506b04e55d622bcc105
Autor:
Jianan Jiang, Jinhua Qin, Jisheng Li, Xiaosong Lin, Bowen Zhang, Zeng Fan, Lijuan He, Quan Zeng, Wen Yue, Min Zheng, Xuetao Pei, Yanhua Li
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Ex vivo production of induced megakaryocytes (MKs) and platelets from stem cells is an alternative approach for supplying transfusible platelets. However, it is difficult to generate large numbers of MKs and platelets from hematop
Externí odkaz:
https://doaj.org/article/da7dd0eb38864173b5933f7fa4b1ca90
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Background Generation of insulin-producing cells from human pluripotent stem cells (hPSCs) in vitro would be useful for drug discovery and cell therapy in diabetes. Three-dimensional (3D) culture is important for the acquisition of mature in
Externí odkaz:
https://doaj.org/article/86771ca499ba43f5a8ac7c9495cf15c8
Autor:
Zehao Niu, Xin Wang, Yujian Xu, Yan Li, Xiaojing Gong, Quan Zeng, Biao Zhang, Jiafei Xi, Xuetao Pei, Wen Yue, Yan Han
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundNecroptosis is crucial for organismal development and pathogenesis. To date, the role of necroptosis in skin cutaneous melanoma (SKCM) is yet unveiled. In addition, the part of melanin pigmentation was largely neglected in the bioinformatic
Externí odkaz:
https://doaj.org/article/77bcf6b7e2f04ad8ba9d8697a542df66
Autor:
Mingyi Qu, Xiaojing Zou, Fang Fang, Shouye Wang, Lei Xu, Quan Zeng, Zeng Fan, Lin Chen, Wen Yue, Xiaoyan Xie, Xuetao Pei
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Platelets derive from megakaryocytes, which differentiate from hematopoietic stem/progenitor cells (HSPCs). Here, Qu et al show that platelet-derived microparticles carrying miR-1915-3p target HSPCs and promote megakaryopoiesis by suppressing RHOB ex
Externí odkaz:
https://doaj.org/article/e57a2830508e4d669bbe1eecb90e8c32