Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Xueran Chen"'
Autor:
Shuyang Li, Wei Wang, Huihan Yu, Siyu Zhang, Wenxu Bi, Suling Sun, Bo Hong, Zhiyou Fang, Xueran Chen
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC) and is the leading cause of cancer death worldwide. Its progression is characterized by genomic instability. In turn, the level of genomic
Externí odkaz:
https://doaj.org/article/f55a09f515634e67a205475eab03816a
Autor:
Zhigang Chen, Dasheng Tian, Xueran Chen, Meng Cheng, Han Xie, JiaJia Zhao, Jun Liu, Zhiyou Fang, Bing Zhao, Erbao Bian
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-13 (2023)
Abstract Long non-coding RNAs (lncRNAs) are tissue-specific expression patterns and dysregulated in cancer. How they are regulated still needs to be determined. We aimed to investigate the functions of glioma-specific lncRNA LIMD1-AS1 activated by su
Externí odkaz:
https://doaj.org/article/e7292f5d80374a998ad97fd04ffc6809
Autor:
Huihan Yu, Meiting Gong, Jian Qi, Chenggang Zhao, Wanxiang Niu, Suling Sun, Shuyang Li, Bo Hong, Junchao Qian, Hongzhi Wang, Xueran Chen, Zhiyou Fang
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background Pyroptosis is a programmed cell death mediated by the gasdermin superfamily, accompanied by inflammatory and immune responses. Exogenously activated pyroptosis is still not well characterized in the tumor microenvironment. Further
Externí odkaz:
https://doaj.org/article/a40d730293d24885985f4b30ca334d9e
Autor:
Chenggang Zhao, Huihan Yu, Xiaoqing Fan, Wanxiang Niu, Junqi Fan, Suling Sun, Meiting Gong, Bing Zhao, Zhiyou Fang, Xueran Chen
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract Glioblastoma stem cells (GSCs) are a highly tumorigenic cell subgroup of glioblastoma (GBM). Glycogen synthase kinase 3β (GSK3β) is considered a key hub for promoting malignant phenotypes in GBM. However, the functional relationships betwe
Externí odkaz:
https://doaj.org/article/b00fd3430baf4050bdc50eec7061e881
Autor:
Erbao Bian, Xueran Chen, Li Cheng, Meng Cheng, Zhigang Chen, Xiaoyu Yue, Zhengwei Zhang, Jie Chen, Libo Sun, Kebing Huang, Cheng Huang, Zhiyou Fang, Bing Zhao, Jun Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background Long non-coding RNAs (lncRNAs) have been considered as one type of gene expression regulator for cancer development, but it is not clear how these are regulated. This study aimed to identify a specific lncRNA that promotes glioma
Externí odkaz:
https://doaj.org/article/28327b0305c148b78c60ad3190fe1e36
Publikováno v:
Oncogenesis, Vol 10, Iss 10, Pp 1-10 (2021)
Abstract Glioblastoma (GBM) is the most common and deadly of the primary intracranial tumors and is comprised of subsets that show plasticity and marked heterogeneity, contributing to the lack of success in genomic profiling to guide development of p
Externí odkaz:
https://doaj.org/article/580bd626cb444845a729c83a2461c16c
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Propofol can have adverse effects on developing neurons, leading to cognitive disorders, but the mechanism of such an effect remains elusive. Here, we aimed to investigate the effect of propofol on neuronal development in zebrafis
Externí odkaz:
https://doaj.org/article/0b37995bd2644702bbd2c0e5c9495ffe
Autor:
Xiaoqing Fan, Haoran Yang, Chenggang Zhao, Lizhu Hu, Delong Wang, Ruiting Wang, Zhiyou Fang, Xueran Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background A large number of preclinical studies have shown that local anesthetics have a direct inhibitory effect on tumor biological activities, including cell survival, proliferation, migration, and invasion. There are few studies on the
Externí odkaz:
https://doaj.org/article/d0f95417de154f1ca516d3c073afe790
Autor:
Xueran Chen, Hao Li, Xiaoqing Fan, Chenggang Zhao, Kaiqin Ye, Zhiyang Zhao, Lizhu Hu, Huihui Ma, Hongzhi Wang, Zhiyou Fang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 518-530 (2020)
Glioblastoma multiforme (GBM) almost invariably acquires an invasive phenotype, resulting in limited therapeutic options. Protein palmitoylation markedly affects tumorigenesis and malignant progression in GBM. The role of protein palmitoylation in GB
Externí odkaz:
https://doaj.org/article/911fe59017df49208a877c597b31a832
Autor:
Erbao Bian, Xueran Chen, Yadi Xu, Xinghu Ji, Meng Cheng, Hongliang Wang, Zhiyou Fang, Bing Zhao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background The epithelial-to-mesenchymal transition (EMT) has been linked to the regulation of glioma progression. However, the underlying signaling mechanisms that regulate EMT are poorly understood. Methods Quantitative real-time PCR (RT-q
Externí odkaz:
https://doaj.org/article/b045793291f54c40b569cdeb1a40b884