Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Xueqing Zou"'
Autor:
Yongmei Wang, Haibo Wang, Yuhua Song, Meng Lv, Yan Mao, Hongming Song, Yuanyuan Wang, Gang Nie, Xiaoyi Liu, Jian Cui, Xueqing Zou
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Despite extensive investigations on photothermal therapy, the clinical application is restricted due to poor stability, low therapeutic efficacy of photothermal therapy agents and its affinity loss in the multistep synthesis of de
Externí odkaz:
https://doaj.org/article/5bb87a9eab0949d69fab91550b6ac8ee
Publikováno v:
Energy Reports, Vol 7, Iss , Pp 4470-4482 (2021)
Offshore oil and gas field development consumes quantities of electricity, which is usually provided by gas turbines. In order to alleviate the emission reduction pressure and the increasing pressure of energy saving, governments of the world have be
Externí odkaz:
https://doaj.org/article/c6a997b9b6584657966051eff821ec88
Autor:
Ping Xiao, Yuhang Pan, Feiyue Cai, Haoran Tu, Junru Liu, Xuemei Yang, Huanling Liang, Xueqing Zou, Li Yang, Jueni Duan, Long Xv, Lijuan Feng, Zhenyu Liu, Yun Qian, Yu Meng, Jingfeng Du, Xi Mei, Ting Lou, Xiaoxv Yin, Zhen Tan
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Purpose: The purpose of this paper is to develop a method to automatic classify capsule gastroscope image into three categories to prevent high-risk factors for carcinogenesis, such as atrophic gastritis (AG). The purpose of this research work is to
Externí odkaz:
https://doaj.org/article/21448ac8f0674e3facdafb67b8c8f918
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Mutational signatures provide a powerful alternative for understanding the pathophysiology of cancer. Currently, experimental efforts aimed at validating and understanding the etiologies of cancer-derived mutational signatures are underway.
Externí odkaz:
https://doaj.org/article/6c395d5c25eb4d99845823b9d0d1d495
Autor:
Helen R. Davies, Kirsty Hodgson, Edward Schwalbe, Jonathan Coxhead, Naomi Sinclair, Xueqing Zou, Simon Cockell, Akhtar Husain, Serena Nik-Zainal, Neil Rajan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
CYLD cutaneous syndrome (also known as Brooke-Spiegler syndrome) is characterised by germline mutations in the tumor suppressor CYLD. Here, the authors highlight recurrent mutations in DNMT3A and BCOR, indicating a role for epigenetic dysregulation i
Externí odkaz:
https://doaj.org/article/455161ea0e7d48609e0545f51dafe8d6
Autor:
Arie B. Brinkman, Serena Nik-Zainal, Femke Simmer, F. Germán Rodríguez-González, Marcel Smid, Ludmil B. Alexandrov, Adam Butler, Sancha Martin, Helen Davies, Dominik Glodzik, Xueqing Zou, Manasa Ramakrishna, Johan Staaf, Markus Ringnér, Anieta Sieuwerts, Anthony Ferrari, Sandro Morganella, Thomas Fleischer, Vessela Kristensen, Marta Gut, Marc J. van de Vijver, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gilles Thomas, Ivo G. Gut, John W. M. Martens, John A. Foekens, Michael R. Stratton, Hendrik G. Stunnenberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
In cancer, global DNA methylation loss and CpG island hypermethylation are commonly observed. Here, in breast cancer the authors find that hyper-variability of partially methylated domains is the prime source of DNA methylation variation and that the
Externí odkaz:
https://doaj.org/article/2a2b3c50b9604a109e1e00c8b53b792f
Autor:
Xueqing Zou, Michel Owusu, Rebecca Harris, Stephen P. Jackson, Joanna I. Loizou, Serena Nik-Zainal
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
As cells evolve towards malignancy, somatic mutations arise from defects in DNA damage and repair processes which are each associated with individual mutation signatures. Here the authors show it is possible to recreate cancer mutational signatures i
Externí odkaz:
https://doaj.org/article/bad9605bd33e4fa186fa37e90cab5f13
Autor:
Sandro Morganella, Ludmil B. Alexandrov, Dominik Glodzik, Xueqing Zou, Helen Davies, Johan Staaf, Anieta M. Sieuwerts, Arie B. Brinkman, Sancha Martin, Manasa Ramakrishna, Adam Butler, Hyung-Yong Kim, Åke Borg, Christos Sotiriou, P. Andrew Futreal, Peter J. Campbell, Paul N. Span, Steven Van Laere, Sunil R. Lakhani, Jorunn E. Eyfjord, Alastair M. Thompson, Hendrik G. Stunnenberg, Marc J. van de Vijver, John W. M. Martens, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gu Kong, Gilles Thomas, Julian Sale, Cristina Rada, Michael R. Stratton, Ewan Birney, Serena Nik-Zainal
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Mutational signatures provide evidence of the mechanism of action of a given mutagen and are found in cancer cells. Here, using 560 breast cancer genomes, the authors demonstrate that mutational signatures are frequently associated with genomic archi
Externí odkaz:
https://doaj.org/article/03b87554fd0b4b03ab41b2913f616ad7
Autor:
Serena Nik-Zainal, Michael R. Stratton, Gu Kong, Jorunn E. Eyfjord, Alastair Thompson, Anne-Lise Børresen-Dale, Andrea L. Richardson, Alain Viari, Xueqing Zou, Dominik Glodzik, Hege Russnes, Elin Borgen, Se Jin Jang, Colin A. Purdie, Sandro Morganella, Helen Davies
Substitution signature exposures estimated in 640 breast cancer WGS and the ovarian sample (AOCS-166).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d18658e292393abe9661cfd1d8f90b
https://doi.org/10.1158/0008-5472.22415168
https://doi.org/10.1158/0008-5472.22415168
Autor:
Serena Nik-Zainal, Michael R. Stratton, Gu Kong, Jorunn E. Eyfjord, Alastair Thompson, Anne-Lise Børresen-Dale, Andrea L. Richardson, Alain Viari, Xueqing Zou, Dominik Glodzik, Hege Russnes, Elin Borgen, Se Jin Jang, Colin A. Purdie, Sandro Morganella, Helen Davies
Mismatch repair (MMR)–deficient cancers have been discovered to be highly responsive to immune therapies such as PD-1 checkpoint blockade, making their definition in patients, where they may be relatively rare, paramount for treatment decisions. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4584d7c3e26ebb0b358b167810ffb299
https://doi.org/10.1158/0008-5472.c.6509189
https://doi.org/10.1158/0008-5472.c.6509189