Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Xueqian Zhuang"'
Autor:
Jingyi Yu, Rong Lei, Xueqian Zhuang, Xiaoxun Li, Gang Li, Sima Lev, Miguel F. Segura, Xue Zhang, Guohong Hu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
SMAD7 is a transcriptional target and a negative regulator of TGFβ signalling forming a negative feedback loop. Here the authors show that in cancer cells TGFβ activates the expression of microRNA-182 that suppresses SMAD7 protein, promoting TGFβ-
Externí odkaz:
https://doaj.org/article/ec0353b3c0b54b89a9b62aad167220c3
Autor:
Xueqian Zhuang, Guohong Hu
Publikováno v:
Bio-Protocol, Vol 8, Iss 11 (2018)
Osteoclasts are a group of bone-absorbing cells to degenerate bone matrix and play pivotal roles in bone growth and homeostasis. The unbalanced induction of osteoclast differentiation (osteoclastogenesis) in pathological conditions, such as osteoporo
Externí odkaz:
https://doaj.org/article/7ff9c014b71e4e00bf516104831f1587
Autor:
Guohong Hu, Qifeng Yang, Dengli Hong, Xiangyin Kong, Lili Mu, Xueqian Zhuang, Jingyi Yu, Yingjie Liu, Jiatao Li, Jing Hu, Yajun Liang
Fig. S1. CSC abundance, expression of ABC transporters and cancer cell chemoresistance after MTDH knockdown or overexpression. Fig. S2. Expression of EMT marker proteins after MTDH knockdown or overexpression. Fig. S3. CSC abundance and in vivo tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a278d099aefb81d02ed701870781883
https://doi.org/10.1158/0008-5472.22407173.v1
https://doi.org/10.1158/0008-5472.22407173.v1
Autor:
Xueqian Zhuang, Simon Joost, Qing Wang, Melissa Blum, Selena Ding, Zhuxuan Li, Yingqian Zhan, Richard Koche, Emily Wong, Tuomas Tammela
Publikováno v:
Cancer Research. 83:B019-B019
This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Short Talks from Proffered Abstracts section (PR010) of the Conference Proceedings. Citation Format: Xueqian Zhuang, Simon Joost, Qing Wan
Publikováno v:
Nat Metab
Unhealthful lifestyle factors, such as obesity, disrupt organismal homeostasis and accelerate cancer pathogenesis, partly through metabolic and immunological dysregulation. Exercise is a prototypical strategy that maintains and restores homeostasis a
Autor:
Qifeng Yang, Peiyuan Zhang, Xiaoxun Li, Yang Yang, Xueqian Zhuang, Min Cong, Hua Xiong, Yingjie Liu, Ronggui Hu, Cheng Lian, Yuan Wang, Xingwang Zhang, Jun Tang, Guohong Hu
Publikováno v:
Nature Cancer. 1:222-234
Tumor-initiating cells (TICs) are considered the culprits of cancer development and progression. Dysregulation of metastasis suppressor protein 1 (MTSS1) has been widely observed in tumor metastasis, but its functional contribution and mechanism in c
Publikováno v:
Trends Pharmacol Sci
Cancer initiates at one site (primary tumor) and, in most cases, spreads to other distant organs (metastasis). During the multistep process of metastasis, primary tumor cells acquire cellular and phenotypic plasticity to survive and thrive in differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60a022ba80688d0a7c94b0199550c72
https://europepmc.org/articles/PMC7518789/
https://europepmc.org/articles/PMC7518789/
Autor:
Fei Chen1, Xueqian Zhuang1, Liangyu Lin1, Pengfei Yu1, Ying Wang1, Yufang Shi1,2, Guohong Hu1, Yu Sun1,3,4,5 sunyu@sibs.ac.cn
Publikováno v:
BMC Medicine. 2015, Vol. 13 Issue 1, p1-13. 14p. 2 Diagrams, 2 Charts.
Autor:
Hong Pan, Rong Lei, Qifeng Yang, Y. Eugene Chin, Yufeng Wang, Xueqian Zhuang, Gang Li, Guohong Hu, Yibin Kang, Xiaoqi Pan, Jing Hu, Qian Tao, Da Fu, Jianru Xiao, Ning Zhang
Publikováno v:
Journal of Clinical Investigation. 124:1646-1659
Bone metastasis is a frequent complication of breast cancer that is often accelerated by TGF-β signaling; however, little is known about how the TGF-β pathway is regulated during bone metastasis. Here we report that deleted in liver cancer 1 (DLC1)
Autor:
Xingwang Zhang, Xiaoyan Li, Qifeng Yang, Xiaoxun Li, Guohong Hu, Fangli Peng, Jingyi Yu, Min Cong, Hao Zhang, Xueqian Zhuang
Publikováno v:
Nature cell biology. 19(10)
Metastatic cancer is a systemic disease, and metastasis determinants might elicit completely different effects in various target organs. Here we show that tumour-secreted DKK1 is a serological marker of breast cancer metastasis organotropism and inhi