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Akademický článek

Multi-omics analysis reveals the prognostic and tumor micro-environmental value of lumican in multiple cancer types

Autor: Zehuai Guo, Zeyun Li, Ming Chen, Xiangjun Qi, Zhe Sun, Siqi Wu, Xuenan Hou, Mengli Qiu, Yang Cao

Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)

Background: Lumican (LUM), a proteoglycan of the extracellular matrix, has been reported to be involved in the regulation of immune escape processes, but the data supporting this phenomenon are not sufficient. In this study, we aimed to explore the l

Externí odkaz: https://doaj.org/article/f420ce5761b6479693b49cdc0bdc8cce

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Xiaoyao powder alleviates the hippocampal neuron damage in chronic unpredictable mild stress-induced depression model rats in hippocampus via connexin 43Cx43/glucocorticoid receptor/brain-derived neurotrophic factor signaling pathway

Autor: Yuanyuan Zhang, Yong Luo, Xuenan Hou, Kang Lu, Yanhong He, Baoying Yang, Yi Qin

Publikováno v: Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 0, Iss 0 (2021)

Xiaoyao Powder (XYP) has been widely applied in China to treat stress-related illnesses, such as migraine, depression, Parkinson’s disease, insomnia, and hypertension. Herein, this study aims to explore the effect of XYP on chronic unpredictable mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7420aa49dec7ca606a2f48179288af47
http://europepmc.org/articles/PMC8805874

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Immunomodulatory mechanism of a purified polysaccharide isolated from Isaria cicadae Miquel on RAW264.7 cells via activating TLR4-MAPK-NF-κB signaling pathway

Autor: Ziying Fan, Shijie Li, Danyan Zhang, Zhanchi Xu, Ruyi Lin, Yuan Zhu, Huanhuan Ma, Xuenan Hou, Weibo Zhao, Jun Wu

Publikováno v: International Journal of Biological Macromolecules. 164:4329-4338

The immunomodulatory effect of a novel purified polysaccharide (JCH-1) isolated from Isaria cicadae Miquel had been confirmed to promote secretion of nitric oxide (NO), tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6) in our previous stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e366caa731db772e43b651d8d71363
https://doi.org/10.1016/j.ijbiomac.2020.09.035

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Inhibitory effect of sinomenine on lung cancer cells via negative regulation of α7 nicotinic acetylcholine receptor

Autor: Shasha Bai, Jiexiu Wu, Yingkun Zhi, Yan Dong, Liang Liu, Pei-xun Wang, Hua Zhou, Xiaoqin Tan, Xuenan Hou, Wenhao Wen, Lang Yi, Yanjun Lv

Publikováno v: Journal of Leukocyte Biology. 109:843-852

Lung cancer is the leading cause of cancer deaths worldwide, with a high morbidity and less than 20% survival rate. Therefore, new treatment strategies and drugs are needed to reduce the mortality of patients with lung cancer. α7 nicotinic acetylcho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa6394e5e6de997dcf31b1dcb7ba96a
https://doi.org/10.1002/jlb.6ma0720-344rrr

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