Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Xuemei Wan"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) is the leading chronic liver disease worldwide. Emerging evidence suggests a close crosstalk between iron status and metabolic syndrome. Therefore, this cohort study aimed t
Externí odkaz:
https://doaj.org/article/b66ab4cda37d4a07b0ecddd7486b368c
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 125 (2024)
Background: The prevalence of laryngeal squamous cell carcinoma (LSCC) is increasing, and it poses a significant threat to human health; therefore, identifying specific targets for LSCC remains crucial. Methods: Bioinformatics analysis was used to co
Externí odkaz:
https://doaj.org/article/72da128891aa470aad1b6c9a4e6081d8
Publikováno v:
Complementary Therapies in Medicine, Vol 70, Iss , Pp 102849- (2022)
Objective: To evaluate the completeness of reporting of acupuncture interventions in trials for functional constipation (FC) following the STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) guidelines. Methods: We searc
Externí odkaz:
https://doaj.org/article/78cd1fa5c48a4991b7ff786408f6795c
Autor:
Wei Xu, Hongchun Li, Liang Wang, Jiamei Zhang, Chunqi Liu, Xuemei Wan, Xiaochong Liu, Yiming Hu, Qiyao Fang, Yuanyuan Xiao, Qian Bu, Hongbo Wang, Jingwei Tian, Yinglan Zhao, Xiaobo Cen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Ketamine is used for sedation and treatment of depression, but is also a drug of abuse. Here the authors show that ketamine modulates the endocannabinoid system in mice, and that this may contribute to its psychoactive effects.
Externí odkaz:
https://doaj.org/article/5d2e1408f3a74c629dd722b4d53c0d12
Autor:
Daphne R. Mattos, Xuemei Wan, Jeffrey D. Serrill, Minh H. Nguyen, Ian R. Humphreys, Benoit Viollet, Amos B. Smith, Kerry L. McPhail, Jane E. Ishmael
Publikováno v:
Marine Drugs, Vol 20, Iss 7, p 418 (2022)
The mandelalides are complex macrolactone natural products with distinct macrocycle motifs and a bioactivity profile that is heavily influenced by compound glycosylation. Mandelalides A and B are direct inhibitors of mitochondrial ATP synthase (compl
Externí odkaz:
https://doaj.org/article/4550626820ff42e8ab85f1dcc9d4b4d9
Publikováno v:
Evidence-Based Complementary and Alternative Medicine. 2022:1-9
Objective. To investigate the effect of cantharidin on DNA damage in hepatocellular carcinoma cells and its possible mechanism. Methods. Cell proliferation assay and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay
Autor:
Yinglan Zhao, Qian Bu, Feng Qin, Hongchun Li, Xiaocong Liu, Rong Chen, Ying Zhao, Shaomin Wang, Shu Li, Yuman He, Xiaowei Yang, Yaxing Chen, Linhong Jiang, Yuanyuan Chen, Rui Xu, Yonghai Wang, Huaqin Zhang, Jiamei Zhang, Hongbo Wang, Qingfan Wei, Xuemei Wan, Yanping Dai, Xiaobo Cen, Haoluo Zhang, Jingwei Tian, Xiaojie Wang
Publikováno v:
ACS Chemical Neuroscience. 12:4449-4464
Cefepime exhibits a broad spectrum of antimicrobial activity and thus is a widely used treatment for severe bacterial infections. Adverse effects on the central nervous system (CNS) have been reported in patients treated with cefepime. Current explan
Abstract LB262: HSK38008: An oral AR-V7 degrader for metastatic castration-resistant prostate cancer
Autor:
Ju Wang, Meilin Qian, Pangke Yan, Linli Li, Chen Zhang, Yan Yu, Lihua Tao, Pingming Tang, Yuting Liao, Xiaogang Chen, Xinfan Cheng, Jinxiong Xu, Xuemei Wan, Luchan Deng, Hongjiao Dong, Haixian Zhang, Maotao He
Publikováno v:
Cancer Research. 83:LB262-LB262
The androgen deprivation therapy (ADT) alone and its combination with hormone therapy that block AR signaling (e.g., enzalutamide or abiraterone) are effective treatments for advanced prostate cancer. Unfortunately, patients with truncated AR splice
Autor:
Yanping Dai, Xiaobo Cen, Zhen Yang, Min Li, Jie Zhang, Hongbo Wang, Linhong Jiang, Jiamei Zhang, Bin Liu, Xuemei Wan, Rong Chen, Wei Xu, Huaqin Zhang, Yonghai Wang, Hongchun Li, Lin Bai, Yuanyuan Chen, Rui Xu, Ying Zhao, Liang Wang, Haoluo Zhang, Jingwei Tian, Yinglan Zhao, Xiaojie Wang
Publikováno v:
Acta Pharmacol Sin
Behavioral sensitization is a progressive increase in locomotor or stereotypic behaviours in response to drugs. It is believed to contribute to the reinforcing properties of drugs and to play an important role in relapse after cessation of drug abuse
Autor:
Ying Zhao, Yanping Dai, Hongchun Li, Wei Xu, Yonghai Wang, Menglu Li, Yuman He, Haoluo Zhang, Rui Xu, Xiaobo Cen, Xuemei Wan, Linhong Jiang, Haxiaoyu Liu, Jiamei Zhang
Publikováno v:
Neurosci Bull
Drug-associated reward memories are conducive to intense craving and often trigger relapse. Simvastatin has been shown to regulate lipids that are involved in memory formation but its influence on other cognitive processes is elusive. Here, we used a