Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Xuemei Gu"'
Autor:
Rui Sun, Chao Lei, Zhishan Xu, Xuemei Gu, Liu Huang, Liang Chen, Yi Tan, Min Peng, Kavitha Yaddanapudi, Leah Siskind, Maiying Kong, Robert Mitchell, Jun Yan, Zhongbin Deng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The tumor microenvironment is reprogrammed by cancer cells and participates in all stages of tumor progression. Neutral ceramidase is a key regulator of ceramide, the central intermediate in sphingolipid metabolism. The contribution of neutr
Externí odkaz:
https://doaj.org/article/dbdcd50178eb47a080743dda553295b3
Autor:
Xuemei Gu, Haoran Wei, Caixia Suo, Shengqi Shen, Chuxu Zhu, Liang Chen, Kai Yan, Zhikun Li, Zhenhua Bian, Pinggen Zhang, Mengqiu Yuan, Yingxuan Yu, Jinzhi Du, Huafeng Zhang, Linchong Sun, Ping Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Itaconate is a well-known immunomodulatory metabolite; however, its role in hepatocellular carcinoma (HCC) remains unclear. Here, we find that macrophage-derived itaconate promotes HCC by epigenetic induction of Eomesodermin (EOMES)-mediated
Externí odkaz:
https://doaj.org/article/4163011c71344526b7413ca7b235ea75
Publikováno v:
Machine Learning: Science and Technology, Vol 5, Iss 3, p 035045 (2024)
Generative Artificial Intelligence (AI) models can propose solutions to scientific problems beyond human capability. To truly make conceptual contributions, researchers need to be capable of understanding the AI-generated structures and extracting th
Externí odkaz:
https://doaj.org/article/c90e96c15f6042b29ce94f16c7d4970d
Publikováno v:
Machine Learning: Science and Technology, Vol 5, Iss 1, p 015029 (2024)
Despite their promise to facilitate new scientific discoveries, the opaqueness of neural networks presents a challenge in interpreting the logic behind their findings. Here, we use a eXplainable-AI technique called inception or deep dreaming , which
Externí odkaz:
https://doaj.org/article/e7684506beda4ff1b4a8f0e2106ccdc2
Autor:
Carlos Ruiz-Gonzalez, Sören Arlt, Jan Petermann, Sharareh Sayyad, Tareq Jaouni, Ebrahim Karimi, Nora Tischler, Xuemei Gu, Mario Krenn
Publikováno v:
Quantum, Vol 7, p 1204 (2023)
Photons are the physical system of choice for performing experimental tests of the foundations of quantum mechanics. Furthermore, photonic quantum technology is a main player in the second quantum revolution, promising the development of better senso
Externí odkaz:
https://doaj.org/article/a0f0154df56d450ea3cd358030c8ec11
Autor:
Xiaozhong Huang, Yujuan Shi, Hongjin Chen, Rongrong Le, Xiaohua Gong, Ke Xu, Qihan Zhu, Feixia Shen, Zimiao Chen, Xuemei Gu, Xiaojun Chen, Xiong Chen
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Abstract Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigat
Externí odkaz:
https://doaj.org/article/029ca09a648f4c9594f70a7429c406ed
Autor:
Shiwei Liang, Chuxu Zhu, Caixia Suo, Haoran Wei, Yingxuan Yu, Xuemei Gu, Liang Chen, Mengqiu Yuan, Shengqi Shen, Shiting Li, Linchong Sun, Ping Gao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Staphylococcal nuclease domain-containing protein 1 (SND1) is an evolutionarily conserved multifunctional protein that functions mainly in the nucleus and cytoplasm. However, whether SND1 regulates cellular activity through mitochondrial-related func
Externí odkaz:
https://doaj.org/article/b1974f6d0b114e53a764c360acd65efc
Autor:
Zhiqiang Li, Xuemei Gu, Danni Rao, Meiling Lu, Jing Wen, Xinyan Chen, Hongbing Wang, Xianghuan Cui, Wenwen Tang, Shilin Xu, Ping Wang, Lei Yu, Xin Ge
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101129- (2021)
‘Don't eat me’ signal of CD47 is activated via its interaction with SIRPα protein on myeloid cells, especially phagocytic cells, and prevents malignant cells from anti-tumor immunity in which pyroglutamate modification of CD47 by glutaminyl-pept
Externí odkaz:
https://doaj.org/article/97de56ea67a04cc58403966a3525a23b
Autor:
Daniel Flam-Shepherd, Tony C. Wu, Xuemei Gu, Alba Cervera-Lierta, Mario Krenn, Alán Aspuru-Guzik
Publikováno v:
Nature Machine Intelligence
Quantum physics experiments produce interesting phenomena such as interference or entanglement, which are core properties of numerous future quantum technologies. The complex relationship between the setup structure of a quantum experiment and its en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd8277f02d28560cf4ec91b9caed339
https://doi.org/10.1038/s42256-022-00493-5
https://doi.org/10.1038/s42256-022-00493-5
Autor:
Yuan Li, Jing Shi, Xia Li, Ying-Xin Li, Xuemei Guo, Meizhu Lu, Xingli Wan, Jun Tang, Biru Luo, Mei Rosemary Fu, Yanling Hu
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Neonatal septic shock represents a critical and life-threatening condition that necessitates immediate and personalized interventions. Prior research endeavors have been undertaken to inform the optimization of neonatal septic sho
Externí odkaz:
https://doaj.org/article/62828c6d07c54e78a2a5fba7e7f49434