Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Xueli Fan"'
Autor:
Qi Tang, Hassan H. Fakih, Mohammad Zain UI Abideen, Samuel R. Hildebrand, Khashayar Afshari, Katherine Y. Gross, Jacquelyn Sousa, Allison S. Maebius, Christina Bartholdy, Pia Pernille Søgaard, Malene Jackerott, Vignesh Hariharan, Ashley Summers, Xueli Fan, Ken Okamura, Kathryn R. Monopoli, David A. Cooper, Dimas Echeverria, Brianna Bramato, Nicholas McHugh, Raymond C. Furgal, Karen Dresser, Sarah J. Winter, Annabelle Biscans, Jane Chuprin, Nazgol-Sadat Haddadi, Shany Sherman, Ümmügülsüm Yıldız-Altay, Mehdi Rashighi, Jillian M. Richmond, Claire Bouix-Peter, Carine Blanchard, Adam Clauss, Julia F. Alterman, Anastasia Khvorova, John E. Harris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Inhibition of Janus kinase (JAK) family enzymes is a popular strategy for treating inflammatory and autoimmune skin diseases. In the clinic, small molecule JAK inhibitors show distinct efficacy and safety profiles, likely reflecting variable
Externí odkaz:
https://doaj.org/article/4a8cb6635b9d4fb98e9074b6bcb3b50f
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 11, Pp n/a-n/a (2023)
Abstract Vascular remodeling is a basic pathological process in various diseases characterized by abnormal changes in the morphology, structure, and function of vascular cells, such as migration, proliferation, hypertrophy, and apoptosis. Various gro
Externí odkaz:
https://doaj.org/article/35b601479ee24f7298f9b7a9738da832
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease that commonly results in nontraumatic disability in young adults. The characteristic pathological hallmark of MS is damage to myelin, oligodendrocytes, and axons. Microglia prov
Externí odkaz:
https://doaj.org/article/44e5b9afeae8439baee0418ab83f160d
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
The gut microbiota plays a key role in the function of the host immune system and neuroimmune diseases. Alterations in the composition of the gut microbiota can lead to pathology and altered formation of microbiota-derived components and metabolites.
Externí odkaz:
https://doaj.org/article/bd098f2c267c4278a500a47778606bfa
Autor:
Sanwang Wang, Hongliang Chen, Xin Wen, Jingjing Mu, Mingyue Sun, Xiaowen Song, Bin Liu, Jinbo Chen, Xueli Fan
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Objective. To study the protective effect of fecal microbiota transplantation (FMT) on experimental autoimmune encephalomyelitis (EAE) and reveal its potential intestinal microflora-dependent mechanism through analyses of the intestinal microbiota an
Externí odkaz:
https://doaj.org/article/c9cb85ed5b384efa9df66ef63aba9f38
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Follicular helper CD4+ T (TFH) cells are a specialized subset of effector T cells that play a central role in orchestrating adaptive immunity. TFH cells mainly promote germinal center (GC) formation, provide help to B cells for immunoglobulin affinit
Externí odkaz:
https://doaj.org/article/d2367afd31ff483ca020262441b2ec98
Autor:
Mingxing Li, Ruifeng Kan, Yabai He, Jianguo Liu, Zhenyu Xu, Bing Chen, Lu Yao, Jun Ruan, Huihui Xia, Hao Deng, Xueli Fan, Bangyi Tao, Xueling Cheng
Publikováno v:
Sensors, Vol 21, Iss 10, p 3392 (2021)
We report the development of a laser gas analyzer that measures gas concentrations at a data rate of 100 Hz. This fast data rate helps eddy covariance calculations for gas fluxes in turbulent high wind speed environments. The laser gas analyzer is ba
Externí odkaz:
https://doaj.org/article/82e3624c51a949999da94957b5aa3c1f
Cdc6 contributes to abrogating the G1 checkpoint under hypoxic conditions in HPV E7 expressing cells
Autor:
Hanxiang Chen, Qishu Zhang, Lijun Qiao, Xueli Fan, Weifang Zhang, Weiming Zhao, Jason J. Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract The human papillomavirus (HPV) plays a central role in cervical carcinogenesis and its oncogene E7 is essential in this process. We showed here that E7 abrogated the G1 cell cycle checkpoint under hypoxia and analyzed key cell cycle related
Externí odkaz:
https://doaj.org/article/04b85512866f468bb2551c1476b8588a
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Macrophages are important immune cells of the innate immune system that are involved in organ-specific homeostasis and contribute to both pathology and resolution of diseases including infections, cancer, obesity, atherosclerosis, and autoimmune diso
Externí odkaz:
https://doaj.org/article/e31d4754b7144a418bd7a31419023f9f
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Objective. This study aimed to examine the potential role of memory T follicular helper (Tfh) cells in patients with neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). Methods. The percentages of different subsets of circulatin
Externí odkaz:
https://doaj.org/article/e8e09ff9fb4b4e4bb2b7bcc9ae74a67b