Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Xuejian Kong"'
Autor:
Huan Wang, Linjie Xie, Haomin Guo, Lishi Li, Shuwei Chen, Ye Fan, Jingyuan Tian, Liping Xu, Xuejian Kong, Aiguo Xuan
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Background N1-Methyladenosine (m1A) is an abundant modification of transcripts regulating mRNA structure and translation efficiency. However, the characteristics and biological functions of mRNA m1A modification in adult hippocampal neurogen
Externí odkaz:
https://doaj.org/article/6a68e3ef82cf47919e60d1da4466f9de
Autor:
Qingfeng Li, Hui Liu, Lishi Li, Haomin Guo, Zhihao Xie, Xuejian Kong, Jiamin Xu, Junlin Zhang, Yunxia Chen, Zhongsheng Zhang, Jun Liu, Aiguo Xuan
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background N7-methylguanosine (m7G) is one of the most conserved modifications in nucleosides impacting mRNA export, splicing, and translation. However, the precise function and molecular mechanism of internal mRNA m7G methylation in adult h
Externí odkaz:
https://doaj.org/article/ba09269219db4160a4021637ec869c5b
Autor:
Zhuo Gong, Jingyi Huang, Biao Xu, Zhenri Ou, Le Zhang, Xiaohong Lin, Xiujuan Ye, Xuejian Kong, Dahong Long, Xiangdong Sun, Xiaosong He, Liping Xu, Qingqing Li, Aiguo Xuan
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metaboli
Externí odkaz:
https://doaj.org/article/b0c99ea370e64368b59421d4f2a0b91e
Autor:
Xi Zhang, Xiaosong He, Qingqing Li, Xuejian Kong, Zhenri Ou, Le Zhang, Zhuo Gong, Dahong Long, Jianhua Li, Meng Zhang, Weidong Ji, Wenjuan Zhang, Liping Xu, Aiguo Xuan
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1256-1269 (2017)
Although valproic acid (VPA), has been shown to induce neuronal differentiation of neural stem cells (NSCs), the underlying mechanisms remain poorly understood. Here we investigated if and how mammalian target of rapamycin (mTOR) signaling is involve
Externí odkaz:
https://doaj.org/article/aae458a3787b424793023366f3903f07
Autor:
Biao Xu, Dahong Long, Xiangdong Sun, Xiaohong Lin, Aiguo Xuan, Zhenri Ou, Xiaosong He, Xuejian Kong, Liping Xu, Qingqing Li, Zhuo Gong, Jingyi Huang, Le Zhang, Xiu-Juan Ye
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation, and impaired neurogenesis. Urolithin A (UA), a gut-microbial metabolite of ell
Autor:
Dahong Long, Zhenri Ou, Biao Xu, Qingqing Li, Xiangdong Sun, Liping Xu, Aiguo Xuan, Xiaohong Lin, Jingyi Huang, Zhuo Gong, Xiaosong He, Le Zhang, Xuejian Kong
Publikováno v:
Brain, behavior, and immunity. 79
Neuroinflammation, considered as a pathological hallmark of Alzheimer's disease (AD), has been demonstrated to affect hippocampal neurogenesis and cognitive function. Interleukin-6 (IL-6) is a proinflammatory cytokine known to modulate neurogenesis.