Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Xuehua Xu"'
Publikováno v:
Virus Research, Vol 349, Iss , Pp 199448- (2024)
Adenoviral infections, particularly in children, remain a significant public health issue with no approved targeted treatments. Artemisinin and its derivatives, well-known for their use in malaria treatment, have shown antiviral activities in recent
Externí odkaz:
https://doaj.org/article/2addc8d113b34be0b621b1cb4b74f1ce
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHuman adenovirus (HAdV) is a common respiratory virus, which can lead to severe pneumonia in children and immunocompromised persons, and canonical inflammasomes are reported to be involved in anti-HAdV defense. However, whether HAdV induc
Externí odkaz:
https://doaj.org/article/8f847e81fadb45e8bc8766ebb46f0d17
Autor:
Xuehua Xu, Henderikus Pots, Bernd K. Gilsbach, Dustin Parsons, Douwe M. Veltman, Sharmila G. Ramachandra, Haoran Li, Arjan Kortholt, Tian Jin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Phagocytosis, macropinocytosis, and G protein coupled receptor-mediated chemotaxis are Ras-regulated and actin-driven processes. The common regulator for Ras activity in these three processes remains unknown. Here, we show that C2GAP2, a Ras GTPase a
Externí odkaz:
https://doaj.org/article/63ae01881cbf47c6a1fbbc45891e3fbe
Autor:
Tingting Shi, Ling Wang, Shuling Du, Huifeng Fan, Minghua Yu, Tao Ding, Xuehua Xu, Dongwei Zhang, Li Huang, Gen Lu
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Some children hospitalized for severe pertussis need intensive care; moreover, some children die because of deterioration alone or in combination with other complications. The purpose of this study was to identify the mortality ri
Externí odkaz:
https://doaj.org/article/0885bdae46434aaaa5ae4b4112555aa1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chemotaxis plays an essential role in recruitment of leukocytes to sites of inflammation. Eukaryotic cells sense chemoattractant with G protein-coupled receptors (GPCRs) and chemotax toward gradients with an enormous concentration range through adapt
Externí odkaz:
https://doaj.org/article/0d7f7c68a5524144935b38bde152675b
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundHuman adenovirus (HAdV) lower respiratory tract infections (LRTIs) are prone to severe cases and even cause death in children. Here, we aimed to develop a classification model to predict severity in pediatric patients with HAdV LRTIs using
Externí odkaz:
https://doaj.org/article/56519347d3964cb788d819060b11d5f2
Autor:
Sijia He, Jia Guo, Yajing Fu, Mark Spear, Chaolong Qin, Shuai Fu, Zongqiang Cui, Wenwen Jin, Xuehua Xu, Wanjun Chen, Hong Shang, Yuntao Wu
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103305- (2021)
Summary: HIV-1 infects blood CD4 T cells through the use of CD4 and CXCR4 or CCR5 receptors, which can be targeted through blocking viral binding to CD4/CXCR4/CCR5 or virus-cell fusion. Here we describe a novel mechanism by which HIV-1 nuclear entry
Externí odkaz:
https://doaj.org/article/c78825a51f2d4c4ca0d788a5bcae008a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
How phagocytes find invading microorganisms and eliminate pathogenic ones from human bodies is a fundamental question in the study of infectious diseases. About 2.5 billion years ago, eukaryotic unicellular organisms–protozoans–appeared and start
Externí odkaz:
https://doaj.org/article/09d138aeafe84652a4457392f0cdf199
Autor:
Bianling Jiang, Guizhen Gao, Mengting Ruan, Ying Bian, Fuyun Geng, Weiwei Yan, Xuehua Xu, Mengdie Shen, Jiafeng Wang, Ran Chang, Lisheng Xu, Xingtao Zhang, Fan Feng, Qiong Chen
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
The wheat seedlings of 6 days old were daily subjected to ultraviolet irradiation (irradiating for 5, 10, 20, 40, and 60 min/day, respectively), Polyethylene glycol 6000 (5, 10, 15, 20, 25% in 1/2 Hoagland solution, respectively), and salinity soluti
Externí odkaz:
https://doaj.org/article/ff4c6ab02dac4e89abfb3f74da09f333
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Chemotaxis, which is G protein-coupled receptor (GPCR)-mediated directional cell migration, plays pivotal roles in diverse human diseases, including recruitment of leukocytes to inflammation sites and metastasis of cancer. It is still not fully under
Externí odkaz:
https://doaj.org/article/44db56350a814b2898bf259d8803f0f1