Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Xuehua Jiang"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Tandospirone citrate (TDS) is commonly used for the treatment of patients with generalized anxiety disorder in clinical practice, and several studies are developing new indications for TDS. However, the in vivo processes and absorption properties of
Externí odkaz:
https://doaj.org/article/cdd3eee42f6543baa9d3b6b9e332ba29
Autor:
Liang Huang, Wei Wei, Xiaomei Huang, Xuejing Li, Haisha Liu, Lanlan Gui, Jinping Jiang, Linfei Wan, Xiangxiang Zhou, Jingsong Ding, Xuehua Jiang, Bikui Zhang, Ke Lan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Ursodeoxycholic acid (UDCA) is a natural drug essential for the treatment of cholestatic liver diseases. The food effects on the absorption of UDCA and the disposition of circulating bile salts remain unclear despite its widespread global
Externí odkaz:
https://doaj.org/article/a6af7250fbdc498ebaecabd1599a0867
Autor:
Wenwen Xu, Mingyu Xu, Yumeng Xiao, Lu Yu, Huiru Xie, Xuehua Jiang, Meiwan Chen, Huile Gao, Ling Wang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 3, Pp 401-411 (2022)
Many studies have shown the influence of protein corona (PC) on the active targeting capability of ligand-modified nanoparticles; however, the influence of clinical status on PC composition and targeting capacity is rarely discussed. In this study, w
Externí odkaz:
https://doaj.org/article/195bba9aa33345e5bafc44e87d84959d
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2703 (2023)
Triple-negative breast cancer (TNBC) is a highly aggressive disease with rapid progression and poor prognosis due to multidrug resistance (MDR). Piperine (PIP) shows promise as a P-gp inhibitor, capable of sensitizing chemotherapeutic drugs and exhib
Externí odkaz:
https://doaj.org/article/e3b11486725e47a5a8deb1a104798034
Publikováno v:
PLoS ONE, Vol 18, Iss 1 (2023)
Objectives Ursodeoxycholic acid (UDCA) is the main therapeutic drug for cholestasis, but its use in children is controversial. We conducted this study to evaluate the efficacy and safety of ursodeoxycholic acid in children with cholestasis. Methods W
Externí odkaz:
https://doaj.org/article/5b3fbf84bd514487a05755ef00b9e866
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Pregnancy is accompanied by significant physiological changes that might affect the in vivo drug disposition. Olanzapine is prescribed to pregnant women with schizophrenia, while its pharmacokinetics during pregnancy remains unclear. This study aimed
Externí odkaz:
https://doaj.org/article/b0c97343779f4a33ad7b95c4fa97cdf0
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Objectives: This study aimed to describe and compare health-related quality of life (HRQoL) among populations with normal glycemic levels, prediabetes, and diabetes in southwest China and to offer baseline data that can be easily compared to other re
Externí odkaz:
https://doaj.org/article/b3fd918852e348dfa9ea69eb74d3adbd
Publikováno v:
Molecules, Vol 27, Iss 24, p 8855 (2022)
Previous studies have shown that silymarin protects against various types of drug-induced liver injury, but whether the protective mechanism of silymarin against acetaminophen-induced liver injury is related to the CYP2E1 enzyme remains unclear. In t
Externí odkaz:
https://doaj.org/article/a3399d1e15104c20b4a858d353040e7f
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Objectives: This study analyzed the long-term cost-effectiveness of fluticasone/umeclidinium/vilanterol triple combination (FF/UMEC/VI) vs. budesonide/formoterol double combination (BUD/FOR) in the treatment of moderate-to-severe chronic obstructive
Externí odkaz:
https://doaj.org/article/efa77685770b43f599e6af4aaa6becb3
Autor:
Wei Xiong, Ling Wang, Haiyan Zhang, Xiaoqiu Tao, Xuehua Jiang, Zejuan Liu, Jiajia Zhao, Wenwen Xu
Publikováno v:
Journal of Analytical Methods in Chemistry, Vol 2021 (2021)
A sensitive and selective ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for the determination of apremilast in beagle dog plasma has been developed and successfully validated in the current study. Clopidogrel wa
Externí odkaz:
https://doaj.org/article/a7bac4b679fe419c9dc9f46af56245c1