Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Xuegu, Xu"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionSulfatinib is a novel oral tyrosine kinase inhibitor (TKI) with selective inhibition of fibroblast growth factor (FGFR), colony-stimulating factor 1 receptor (CSF-1R) and vascular endothelial growth factor receptor (VEGFR) 1, 2, and 3. It
Externí odkaz:
https://doaj.org/article/5ea0dc0c17c64a22893332fdae6ae45f
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 621-626 (2022)
Context Tucatinib (CYP2C8 substrate) and quercetin (CYP2C8 inhibitor) are two common drugs for the treatment of cancer. However, the effect of quercetin on the metabolism of tucatinib remains unknown.Objective We validated a sensitive method to quant
Externí odkaz:
https://doaj.org/article/cdceea949067450aabe0c09477d73b8d
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
As the validated agent for the treatment of chronic myelogenous leukemia (CML), flumatinib is a novel oral tyrosine kinase inhibitor (TKI) with higher potency and selectivity for BCR-ABL1 kinase compared to imatinib. Many patients experience aspergil
Externí odkaz:
https://doaj.org/article/2b20fbd654ce4770919ac3aa1ca0d47c
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 7, Pp 103893- (2022)
Infigratinib (INF) is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor for the therapy of advanced cholangiocarcinoma. However, CYP3A4 polymorphisms and CYP3A4 inducers or inhibitors might affect the pharmacokinetics of I
Externí odkaz:
https://doaj.org/article/98870aac3b1e40d69cad93c64754bc79
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 12, Pp 103430- (2021)
The prime purpose of this research currently being done was to set up an acceptable and high-operational ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method, which could simultaneously analyze the concentration levels
Externí odkaz:
https://doaj.org/article/f2ae2579474a4a1cadb26298625b4b4b
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 8, Pp 103300- (2021)
The purpose of the experiment was mainly to establish and verify a precise and straightforward ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) approach for simultaneously analyzing the concentration levels of amiodarone,
Externí odkaz:
https://doaj.org/article/0b00a5d81a774c8da02c9082d28ff12e
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 6, Pp 103152- (2021)
Avapritinib, an orally consumed, highly selective inhibitor of platelet-derived growth factor receptor alpha (PDGFRA), is approved in the USA for PDGFRA exon 18 (including D842V) mutant gastrointestinal stromal tumour (GIST). The research conducted i
Externí odkaz:
https://doaj.org/article/514e1b849dfb4c1eb1999ffa76c3896a
Publikováno v:
Journal of Biomedical Nanotechnology. 17:1939-1950
We prepared poly(lactide-co-glycolide) (PLGA) encapsulated with chlorin e6 (Ce6) in an effort to increase the stability and efficiency of photosensitizers for photodynamic therapy (PDT). We determined that Ce6-loaded PLGA nanoparticles (PLGA-Ce6 NPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafb2a03ee3db58e58bd72fc5bdaf27f
https://doi.org/10.1166/jbn.2021.3170
https://doi.org/10.1166/jbn.2021.3170
Publikováno v:
Ocular Immunology and Inflammation. 30:1341-1346
Under various physiological conditions, endoplasmic reticulum stress can induce apoptotic cell death, leading to brain and retinal neuronal cell death, but the relations of ER stress-induced apoptosis and the nerve growth factor's therapeutic effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2b88a3a5d16c43a560a883d0602b95
https://doi.org/10.1080/09273948.2021.1872651
https://doi.org/10.1080/09273948.2021.1872651
Publikováno v:
Inflammopharmacology
Objective B6, an analog of curcumin, is a compound isolated from a traditional Chinese medicine Turmeric. In this paper, we aimed to explore the efficacy of B6 on diabetic nephropathy and the related mechanisms. Materials and methods The effects of B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edc2f95092a8b749ad01ac4b0e6bdf1
http://europepmc.org/articles/PMC6153927
http://europepmc.org/articles/PMC6153927